Gene Information

Name : hemC (Clim_0893)
Accession : YP_001942951.1
Strain : Chlorobium limicola DSM 245
Genome accession: NC_010803
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 977947 - 978888 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAAAAAACAGCTTATTATCGGTACCAGATCCAGCCCGCTTGCCCTGTGGCAGGCAGAATTCACCAAAGCGGAGCTTTC
GAGGCATTTTCCGGAACTCGACATTACCCTTAAACTGGTCAAGACAACCGGCGACGTGCTTCTTGATTCACCGCTTTCCA
AAATCGGTGATATGGGTTTGTTCACCAAGGACATTGAAAAGCATCTGATTGCAAAAGAGATCGATCTTGCTGTCCACAGT
TTGAAGGATGTTCCGACGAGCACTCCCGAAGGCCTTATCATCACCTCGTTTACCGAACGTGAGGATACGAGGGACGTCAT
CATTTCCAAAGGCGGAGCAAAACTTGCCGATCTGCCGCTGAATGCAAAAGTTGCAACAAGCAGCCTTCGACGCATGTCGC
AGCTCAAGAGCCTCCGTCCGGATTTTGAAATCTGCGACATCAGAGGCAATCTCAACACCAGATTCAAGAAGTTCGACGAA
GGTGAATTCGATGCCATGATGCTTGCTTATGCCGGTGTTTTCCGTTTGAATTTCAGCGACCGTATCTCGGAAATCCTGCC
GCATGAGATCATGCTCCCCGCCGTAGGGCAGGGCGCTCTTGGTATTGAAACCCGTGTCGATGACGAACAGACCAGGGAAA
TCGTCAGAATTCTCAACCATTCCAACACCGAGTATTGCTGCAAAGCGGAACGTGCTCTCCTTCGCCATCTGCAGGGAGGT
TGCCAGATACCGATCGGGGCCTATGCTTCCTTCAAGAACGGCACCCTCAAGCTTCTTGCATTTGTCGGATCCGTTGACGG
TACCGTCGGGATCAACAACGAGATTACCCGTAGCGGACTCACCTCTCCCGATCAGGCGGAAGAAGCCGGTATTGCGCTTG
CAGAAGAACTGCTGAAACAGGGAGCGGACAAGATTCTTTCAGAAATCCGCAAAACCCGCTGA

Protein sequence :
MKKQLIIGTRSSPLALWQAEFTKAELSRHFPELDITLKLVKTTGDVLLDSPLSKIGDMGLFTKDIEKHLIAKEIDLAVHS
LKDVPTSTPEGLIITSFTEREDTRDVIISKGGAKLADLPLNAKVATSSLRRMSQLKSLRPDFEICDIRGNLNTRFKKFDE
GEFDAMMLAYAGVFRLNFSDRISEILPHEIMLPAVGQGALGIETRVDDEQTREIVRILNHSNTEYCCKAERALLRHLQGG
CQIPIGAYASFKNGTLKLLAFVGSVDGTVGINNEITRSGLTSPDQAEEAGIALAEELLKQGADKILSEIRKTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-56 49
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-56 49