Gene Information

Name : Clim_0667 (Clim_0667)
Accession : YP_001942729.1
Strain : Chlorobium limicola DSM 245
Genome accession: NC_010803
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 739367 - 740512 bp
Length : 1146 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: cph:Cpha266_0732 cystathionine gamma-synthase

DNA sequence :
ATGCAGTTCGAAACCCTCGCAATTCATGACGGACAAACCCCCGACCCGCAGACCGGGTCGGTAACGGTTCCGGTTTTTCA
GACCTCGACGTTCGAGCGCGAAGACCTCTCACATCGTCGGGAGTTCTTTTATTCGAGAATCGGAAACCCGACACGACAGG
CTCTCGAATCGACCCTGGCCCTGCTTGAAAACGGACGATTCGGCCTCGCTTTCGCATCAGGCGCTGCAGCAACCATGGCT
GCCCTGCAGGTACTCAGGCCAGGCGACCATATCGTATCCGCTCTCGATATTTACGGAGGTACCTACCGGATTTTCGAACA
GCTCCTGCGTCCCTGGGGCATCGGCATATCCTACGCCGACAATGAAGCTGTCGAGAGTTATGCCGCCTGTATCGTCCCTG
AAACAAAACTCATCTGGCTGGAAAGCCCCAGCAACCCGCTGCTCAGGCTCTCGGACATCCGCGAAATCGCCTCGCTTGCC
CGTGAACGCGGCATCCTCGTTGCCGTTGACAACACCTTTGCAAGTCCGTACTTTCAGCGACCCCTCGAACTCGGTGCCGA
CATCGCGGTACACAGCACCACCAAATATCTCGGGGGCCACAGCGACGTAATCGGAGGAGCCGTTGTCCTTAACGACCCGG
CACTGCTCACCACCATCAAAAACTACCAGGCCGCCGCCGGAGCCATACCCGGCCCGTGGGACTGCTGGCTCATCATGCGC
GGCATCAAAACACTTAAAATCCGCATGAAAGAGCACGAAGCCAACGCCCTGCATCTGGCGCAACTGCTCGAAGGGCATCC
GGCAGTCGAGCGCGTCTGGTATCCCGGACTTCCCTCGCATCCGCAGCATGAACTGGCAAAACGCCAGATGAGCGGGTTCA
GCGGCATGCTGACCTTTGCACTTAAAGGCGGACTTCCTGCTGTCGAGCTGCTGCTTGCAAAACTCAAGCTCTTCGCTCTT
GCCGACAGTCTCGGCGGAGTCGAATCGCTCGTAGCCTCGCCGGCTAAAATGACGCTTGGAGCGCTCTCGGCCAAAGAGCG
CACTAAACGCGGCTGCAGCGACAATCTTGTGCGCATGTCGGTCGGACTGGAATATGCCGGAGATCTCGAAGCCGATCTGC
TGACGGCGCTTTCCGCCCTGCAATAA

Protein sequence :
MQFETLAIHDGQTPDPQTGSVTVPVFQTSTFEREDLSHRREFFYSRIGNPTRQALESTLALLENGRFGLAFASGAAATMA
ALQVLRPGDHIVSALDIYGGTYRIFEQLLRPWGIGISYADNEAVESYAACIVPETKLIWLESPSNPLLRLSDIREIASLA
RERGILVAVDNTFASPYFQRPLELGADIAVHSTTKYLGGHSDVIGGAVVLNDPALLTTIKNYQAAAGAIPGPWDCWLIMR
GIKTLKIRMKEHEANALHLAQLLEGHPAVERVWYPGLPSHPQHELAKRQMSGFSGMLTFALKGGLPAVELLLAKLKLFAL
ADSLGGVESLVASPAKMTLGALSAKERTKRGCSDNLVRMSVGLEYAGDLEADLLTALSALQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-68 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-69 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-58 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Clim_0667 YP_001942729.1 cystathionine gamma-synthase BAC0207 Protein 1e-57 44