Gene Information

Name : guaA (Clim_0241)
Accession : YP_001942315.1
Strain : Chlorobium limicola DSM 245
Genome accession: NC_010803
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 269707 - 271248 bp
Length : 1542 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAATCAGTTCTCGTGCTGGACTTCGGTTCACAATACACTCAGCTTATCGCACGCCGTATAAGGGAACTCGGCATTTA
TTCCGAAATTCTGCCCTATAACACAACGCCAGAGACAATCAGGGAACACGCCCCGAAAGCGATCATCCTTTCGGGAGGCC
CTACCAGCGTCTATGGAGAATCCGCCATTCTTCCCCACGAAGGCATCTTTTCGCTCGGGTTGCCGATTCTCGGAATCTGT
TACGGCCTGCAGGCCATAGCCAAACACTTCGGCGGAGAGGTGGCCTCTTCGGCCAAGCAGGAGTTCGGCCGGGCGAAAAT
GCTGGTCAGCCGTGACGGCGAGCCTGAAAGCATGCTCTTCCGCAACATTCCGGACTCGGATGTCTGGATGAGCCACGGCG
ACAAGGTGGTCAATCTTCCCGATGGGTTCAGAATCACGGCAAGCAGCGCGAATTCCGAAATGTGCGCGCTTGAAACTTAC
GGAAGCAAGGGCGCACTGAAGGTGTTCGGCCTGCAGTTCCACCCTGAAGTGCAGCATACCCTGTACGGAAAACAACTGCT
CTCGAACTTCCTTATCGATATCGCGGGCATTACCCCCGACTGGTCGCCGAAACACTTTATCGATCATCAGATCGAGGAGA
TACGCAGAACAGCCGGCGACGAAACCGTTATCTGCGGCATCAGCGGAGGCGTCGACTCTTCTGTCGCAGCCGTCCTGGTC
AGCAGGGCCATCGGAAAAAACCTGCACTGCGTCTTTGTCGACAACGGCCTCCTGCGCAAAAACGAGGCTGACAAGGTAAT
GCAATTTCTCAAGCATCTCGGACTCCGGCTCACGCTGGCCGATGCTTCGGAGCTTTTTCTCAAGCGATTGAAAAACGTGG
CTTCGCCCGAAAAGAAACGCAAGATTATCGGCAGAACCTTCATTCAGGTGTTCGAAGAACAGCTGGATAAAGAAAAATTC
CTGGTACAGGGCACCCTCTACCCCGACGTCATTGAAAGCGTCAGCGTAAAAGGGCCGTCCGAAACCATCAAGTCACACCA
TAATGTCGGCGGACTGCCCAAACGCATGAAGCTGAAGCTGATCGAACCGCTTCGTGAACTGTTCAAGGACGAAGTGCGGG
CGGTCGGACGCGAGCTCGGCATAGCCGAGGACATTCTCATGCGCCACCCCTTCCCCGGTCCCGGCCTTGCCGTAAGGGTG
CTCGGTTCGGTCAGCAAGGAACGGCTCGATATTCTGCGCGATGCCGACGAAATCTTTCTCGAAGAGCTGAAATCGAGCGG
CCTCTACCAGAAGGTCTGGCAGGCGTTCTCCGTGCTCCTGCCGGTACAGTCGGTCGGCGTGATGGGCGACAAGCGCACCT
ACGAAAACGTGCTCGCGCTCCGGGCCGTGGAGTCGTCGGACGGCATGACCGCCGACTGGGCGCAGCTTCCCCACGACTTC
CTTGCCCGCGTCTCGAACCGCATCATCAACGAAGTCAGGGGCATCAACCGGGTGGCCTACGATATCTCCTCGAAACCGCC
GGCAACGATCGAGTGGGAGTAA

Protein sequence :
MQSVLVLDFGSQYTQLIARRIRELGIYSEILPYNTTPETIREHAPKAIILSGGPTSVYGESAILPHEGIFSLGLPILGIC
YGLQAIAKHFGGEVASSAKQEFGRAKMLVSRDGEPESMLFRNIPDSDVWMSHGDKVVNLPDGFRITASSANSEMCALETY
GSKGALKVFGLQFHPEVQHTLYGKQLLSNFLIDIAGITPDWSPKHFIDHQIEEIRRTAGDETVICGISGGVDSSVAAVLV
SRAIGKNLHCVFVDNGLLRKNEADKVMQFLKHLGLRLTLADASELFLKRLKNVASPEKKRKIIGRTFIQVFEEQLDKEKF
LVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIAEDILMRHPFPGPGLAVRV
LGSVSKERLDILRDADEIFLEELKSSGLYQKVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESSDGMTADWAQLPHDF
LARVSNRIINEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-129 50
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-129 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-129 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-123 49