Gene Information

Name : Clim_2038 (Clim_2038)
Accession : YP_001944046.1
Strain : Chlorobium limicola DSM 245
Genome accession: NC_010803
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2249594 - 2250337 bp
Length : 744 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAATGCCGTTATCCTGATTCCTGCGCGGCTCGATTCGAGCCGGCTTCCGAAGAAGATGCTTGCCGACCTTGACGGCGA
ACCGCTGATCGTGCGTACCTGGCGTCAGGCGCTGCTGTCGAACCATGCCGTGCGGGTCGTCGTGGCTACAGACAGCCCGG
AGATAGCCGGGGCTCTCGAAGCGTACGGCGCGGAAGTGATGATGACGTCGCCTCACGCCCGTTGCGGTACCGAACGTATC
GCCGAAGCGGCGCGAAGCATCGATGCGGACGTTTTTCTCAATCTGCAGGGTGATGAGCCGCTGATCGATCCCCGGAATAT
CGATCTCTGTCTGGAACCGTTTCTTGCCGATAATCCGCCGGACTGTTCCACTCTGGTCTATCCGCTTCTGCCGGAGGATT
TTCAGCAGATCGATGATCCCAATGTCGTCAAGGTCGTACTCGACAGAAACGGCAATGCGCTCTATTTTTCACGGAGTCCG
GTGCCCTTTCAGCGGGAGGTGTATGCCGCGACGCAGTTCTACCGCCATATAGGGCTCTACGCATTCTCTGCCGAAGTCCT
GCAGCACTATGCTTCGCTGCCCCCTTCGATGCTGGAAAAAGCCGAATCGCTCGAACAGCTCCGACTGCTGGAAAACGGAT
TCAGCATTCGATGCGTCACTACAACCGTCGATCATCCGGGGGTCAATACCCCTGAAGATCTCGATCTGGTCCGCAGAATG
CTCAGGAGGTCGGCGGGCCGGTGA

Protein sequence :
MNAVILIPARLDSSRLPKKMLADLDGEPLIVRTWRQALLSNHAVRVVVATDSPEIAGALEAYGAEVMMTSPHARCGTERI
AEAARSIDADVFLNLQGDEPLIDPRNIDLCLEPFLADNPPDCSTLVYPLLPEDFQQIDDPNVVKVVLDRNGNALYFSRSP
VPFQREVYAATQFYRHIGLYAFSAEVLQHYASLPPSMLEKAESLEQLRLLENGFSIRCVTTTVDHPGVNTPEDLDLVRRM
LRRSAGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-42 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 9e-42 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-42 42