Gene Information

Name : lysS (Clim_1586)
Accession : YP_001943610.1
Strain : Chlorobium limicola DSM 245
Genome accession: NC_010803
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1707578 - 1709101 bp
Length : 1524 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCCGAAAGAGAACCAGCACCAGGAACAACCTCAGCAACTCTCGCTCAACGACCAGATGCAGCGCCGCCATGAAGAGCG
CCGACACCTTGCGGAATCAGGAATCAATCCCTATCCCTGCACCTTCGACGTAACGGCCTGTTCAACCGATATCACCACCT
CATTTCAGGATGAACAGCGTAAACAGGTATCGGTTGCCGGCAGGATCATGACCATACGAAAAATGGGAAAAGCCTCTTTT
TTCCATATCCAGGACTCAAAAGGACGAATTCAGGTCTATCTGAAGAAAGACGATGTCGGAGAAACCGCGTACAACACCTT
CAAGCTGCTGGATATCGGCGATATCGTCGGAGTGAAAGGGTTTACCTTCAGAACGAAAACCGGCGAAATCTCCGTCCATG
CCGAAACGTTCGAGCTGCTCAGCAAATCGTTGCGTCCTATTCCGGTAGCCAAAGAGAAGGATATAGACGGTCAGAAAGTG
GTATATGACGCCTTCAGCGACAAGGAGCTTCGTTACCGCCAGCGTTACGTCGACCTGATCGTCAATCCCGAAGTGAGGGA
AACCTTCATCAAACGCTCGGCAATCGTCACATTCATGCGCCAGTTCTTTACCGGGAAGGGATGGCTTGAAGTTGAAACCC
CGATTCTGCAGCCGATCTACGGAGGAGCGGCGGCCAGACCGTTTACGACCCACCACAACGCTCTTGACATGCAGCTCTAT
CTGCGCATAGCCAACGAGCTCTATCTCAAACGCCTCATCGTTGGCGGGTTTGACGGTGTTTTCGAGTTCGCCAAGGATTT
CCGCAACGAAGGCATAGACCGCTTCCACAATCCTGAGTTCACCCAGGTTGAGCTCTATGTAGCCTACAAGGACTACAACT
GGATGATGGAACTTGTCGAGGAGCTGCTCTACCGAACCACTCTCAGCGTCAACGGGACGCACACCACCAGTTTCCTCGGT
AATGATATCTCCCTTGAACCGCCATTCAGACGCTTGACCATTGTCGACGCGATCAAGGAGTACTGCAATGTGGACGTCAG
CGGCAAAAACGAAACCGAACTGCGTTCTGCGGCCAAGGATCTCGGTCTGGAACTCGACCCGAAAATCGGTGCGGGAAAAA
TCATCGATGAAATCTTCGGCGAATTTGTAGAGCCGAAGCTCATTCAGCCGACCTTCATTACAGACTACCCGACCGAAATG
TCGCCGCTTGCCAAGGAACACCGCTCGAAACCCGGCTTCGTCGAACGGTTCGAACTGATAGCCGGCGGAAAGGAACTCTG
CAACTCTTTCTCTGAGCTGAACGATCCGGTCATCCAGCGCGAGCGACTCGAATCGCAGGCGAAGCTGCGCCTTCGCGGCG
ATGAGGAAGCCATGGTGGTGGATGAGGATTTCCTCCGGGCTCTCGAATACGGCATGCCGCCCTGCGCCGGGCTCGGTATA
GGCATCGATCGGGTAGTCATGCTGATTACCGGACAGGAATCAATTCGTGATGTGATTTTTTTCCCGCATCTGAAACCGGA
ATAG

Protein sequence :
MPKENQHQEQPQQLSLNDQMQRRHEERRHLAESGINPYPCTFDVTACSTDITTSFQDEQRKQVSVAGRIMTIRKMGKASF
FHIQDSKGRIQVYLKKDDVGETAYNTFKLLDIGDIVGVKGFTFRTKTGEISVHAETFELLSKSLRPIPVAKEKDIDGQKV
VYDAFSDKELRYRQRYVDLIVNPEVRETFIKRSAIVTFMRQFFTGKGWLEVETPILQPIYGGAAARPFTTHHNALDMQLY
LRIANELYLKRLIVGGFDGVFEFAKDFRNEGIDRFHNPEFTQVELYVAYKDYNWMMELVEELLYRTTLSVNGTHTTSFLG
NDISLEPPFRRLTIVDAIKEYCNVDVSGKNETELRSAAKDLGLELDPKIGAGKIIDEIFGEFVEPKLIQPTFITDYPTEM
SPLAKEHRSKPGFVERFELIAGGKELCNSFSELNDPVIQRERLESQAKLRLRGDEEAMVVDEDFLRALEYGMPPCAGLGI
GIDRVVMLITGQESIRDVIFFPHLKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-98 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001943610.1 lysyl-tRNA synthetase VFG1668 Protein 7e-99 47