Gene Information

Name : serS (OTT_0428)
Accession : YP_001937120.1
Strain : Orientia tsutsugamushi Ikeda
Genome accession: NC_010793
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 444278 - 445567 bp
Length : 1290 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGACATAAAATGGATTAGAGCAAACCCAGATAAACTTGATGAATCACTAAGCAAACGAGGAATCGATTCAGTATC
TAAATCAATAATACATATTGATTCAGAAAAAAGAACATTAATATCTCTAATTCAGAAATTACAGCATGAAAGAAAAGAAA
AATCTAGTAGTGTAGCACATATTTATGACAAATCAAGTACTGATTTTGAAGAAATACAAAACGATGTTAAGCTGATCAAT
CAAAAGATAACTGAATTAGAAACTTCATTATTGCATCATGAAAAAAGGTTATCTGAGATTATGGATAACCTTCCTAATTT
AGTAGCTGATGATGTACCTTATGGTACTAATAGTGATATGAATAAAGTGCTTAAAGAATGTGGCACAATTCAAAATATCA
AATTCCCAAAACATCATTATGAAATTGGAAAAAATTTAGGAATGATGGATTTTAATACAGCTACTAAGATGTCAGGAAGT
AGGTTTGTAATTTTAAAACATGATCTTGCGAAACTTGAAAGAGCTTTAATCAATTTTATGATTGATGTACATACTACTGA
GTTTAATTTTTTTGAAGTTTCTCCGCCATGCTTAGTTAAGGATCATGCTATGTATAATGTTGGCCAACTACCTAAATTTG
CTGATGCATCATTTGAGACTACAACTGGATATAGATTGATACCTACTGCAGAAGTGCCATTAACTAATATTTTTGCTAAT
ACTACTTTATTAGAAGAAAAATTACCAATAAGATTGGTAGCGTTTACTCCTTGCTTTAGATCAGAAGTAGGAAGCGCTGG
TAAAGACGTTAAAGGTATGTTGCGAATGCATCAATTTGGCAAAGTAGAGCTTTTTACTATCGCTACACCTAAAGAATCAA
ATAGAGAATTTGAGTATCTTACTGCTGCTGCTGAAAAAATTCTAGAGAAATTAGGGTTACCATATAGAGTAGTATTATTA
TGTAGCGGTGATATAGGATTTGCAGCTCATAAAACATATGATCTTGAAGTGTGGTTACCAGCACAAAATTGTTATAGAGA
AATTTCAAGCTGTTCACATTTTAGTTCTTTTCAAGCTAGAAGATCACTAAGTAAATATAGAGAACTTTGCTCTAAAAAAG
TTAATTTTCTACATACAATCAATGGATCCGGACTTGCTGTTGGAAGAACTATAATTGCTATTCTAGAAAATTATCAAAAT
TCAGATGGATCAGTTACAATTCCTGAAAAGCTTAGGAATTACATGGGAGGACAGAAACTGATTACACCTTTAACAGAAAC
AGTATTTTGA

Protein sequence :
MLDIKWIRANPDKLDESLSKRGIDSVSKSIIHIDSEKRTLISLIQKLQHERKEKSSSVAHIYDKSSTDFEEIQNDVKLIN
QKITELETSLLHHEKRLSEIMDNLPNLVADDVPYGTNSDMNKVLKECGTIQNIKFPKHHYEIGKNLGMMDFNTATKMSGS
RFVILKHDLAKLERALINFMIDVHTTEFNFFEVSPPCLVKDHAMYNVGQLPKFADASFETTTGYRLIPTAEVPLTNIFAN
TTLLEEKLPIRLVAFTPCFRSEVGSAGKDVKGMLRMHQFGKVELFTIATPKESNREFEYLTAAAEKILEKLGLPYRVVLL
CSGDIGFAAHKTYDLEVWLPAQNCYREISSCSHFSSFQARRSLSKYRELCSKKVNFLHTINGSGLAVGRTIIAILENYQN
SDGSVTIPEKLRNYMGGQKLITPLTETVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-93 47