Gene Information

Name : hemC (OTT_1638)
Accession : YP_001938330.1
Strain : Orientia tsutsugamushi Ikeda
Genome accession: NC_010793
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 1667750 - 1668646 bp
Length : 897 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGATTATTAGAGTAGGTAGTAGAGCAAGCAGATTGGCATTGATACAGGCGCAAGCAGTAGTTCAAAAAATTAATGATTT
ACTTGGGTTAAATGCTATAATAATTCCTATTAAAACTACTGGTGATTTAATTCAGAATAAAAACCTTTATGATATAGGAG
GCAAGGGCCTATTTTTAAAAGAAATAGAGTATGCTTTATTAAATAATACTATTGATATTGCTGTTCATTCCTTAAAAGAT
GTACCAGCTTATTTACCTGATGGATTACAACTTGCAGCTGTACTAGAAAGGGGGAATGTTGGCGATATGCTTGTATCTAA
AATAGCAAATAAAATTACTGACTTACCTTTAGGGGCTAGAGTTGGCACTTCTTCTGTACGAAGACGAATACAGCTATTAA
GGCTTCGGCCTGATCTTAATATCGTGTTATTTAGAGGTAATGTTGATACTAGATGGAATAAAATTTTCAATAATGAGGTA
GATGCAACAGTTTTGGCTGCTGCTGGACTACAGAGATTGAATTATGATACTAGCCGTTTTTGTAATATTATTTCTCAAGA
TGAGATGTTGCCAGCAATTGGGCAAGGCGTAATTGCAATCGAAGCTAGAAAAGATGATAAACTAATAATGCCATTATGTG
CTAAAATTAATCATCAGTTAACTTGGCAATTAATACAAGTTGAAAGAGGTTATTTAAAAACTTTAAATGCCGATTGTAAC
GTTCCAATAGGTGGGCTTGCAAACTATATTGGTAATAATAATTTTGAGGCTAAATTTATGCTTGGAGATTATAATATGAG
ATATTTTTTTTATTCTGAGGTGTGTGGAAAGTTACAGCATGGTTACGATATTGGAGTTGAAGCAGCAAAAAACTTTCAAA
AAAAATTATTTGTCTGA

Protein sequence :
MIIRVGSRASRLALIQAQAVVQKINDLLGLNAIIIPIKTTGDLIQNKNLYDIGGKGLFLKEIEYALLNNTIDIAVHSLKD
VPAYLPDGLQLAAVLERGNVGDMLVSKIANKITDLPLGARVGTSSVRRRIQLLRLRPDLNIVLFRGNVDTRWNKIFNNEV
DATVLAAAGLQRLNYDTSRFCNIISQDEMLPAIGQGVIAIEARKDDKLIMPLCAKINHQLTWQLIQVERGYLKTLNADCN
VPIGGLANYIGNNNFEAKFMLGDYNMRYFFYSEVCGKLQHGYDIGVEAAKNFQKKLFV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-37 44
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-37 44