Gene Information

Name : guaA (SYO3AOP1_1628)
Accession : YP_001931780.1
Strain : Sulfurihydrogenibium sp. YO3AOP1
Genome accession: NC_010730
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1687164 - 1688699 bp
Length : 1536 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCATCGAGGAATAGTAATTTTAGATTTTGGTTCTCAATATACCCAGTTAATAGCAAGAAGGATAAGAGAGTTAAATGT
CTACAGCGAGATTTTGCCGTTTAACGCATCAGTAGAAGAGATACTAAAACATAATCCAAAAGGAATAATATTTTCTGGTG
GTCCTGCTTCTGTTTATGAACCTGATGCACCTAAGCCAGATGAAAAAGTTTATGATTTAGGGTTGCCTATTCTTGGAATT
TGTTATGGACTTCAGCTTATAACACATCATTTTGGTGGAGAAGTAATAAAAGCTGATAAGCATGAGTATGGTAAAGCCGA
GTTAGAAGTTTTAGATCATGAAGACCTTTTTTATAATATCCCACACTATACACAAGTTTGGATGAGTCATGCAGATAAAG
TAATAAAACTACCAGAAGGTTTCGAAGTAATCGGCAGAACGTTCAACGCACCTTTTGCGGCCGTAAGAAACAAAGAAAAG
AAAATTTGGGGCGTTCAGTTTCATCCGGAAGTAAGCCATACACTTCTTGGTAAAGAAATGCTGAAAAACTTTGCAGTCAG
AATTTGTAAATGTAAACAAGATTGGACTATGGGCAATTTCTTAATGGAAAAACAGGTTGAAATAAGAAAAATGGTAGGTG
ACAAAAAAGCAATCTGTGCTTTGTCTGGTGGAGTTGATTCGTCCGTTGCTGCGGTTTTGGTTCATAATGCGATTGGAGAT
AATTTAACTTGCATCTTTGTTGACAATGGACTTTTGAGAAAAGGTGAAAGAGAACAGGTAGAAAAAACATTTAGAGACAA
TTTCCATATTTCATTGATAGTAGTAGATGCAAAAGATAGGTTTTTAAAGGCATTAAAAGGAATCACAGACCCAGAGCAAA
AGAGAAAGATAATCGGTAATCTTTTTATAGAAGTCTTTGAAGAAGAAGCGAAAAAATTAAAAGATGTGGAATACTTAGTT
CAAGGCACATTGTATCCGGACGTTATAGAAAGCGTATCAGTTAAAGGGCCATCAGCAGTTATTAAAACTCACCATAACGT
TGGCGGATTGCCGGAAAGAATGAACTTAAAGCTTATAGAACCGCTAAGAGAGTTATTCAAAGATGAAGTAAGAGAGCTTG
GCAAAGAGCTTGGATTGCCAGAAGAGATTATTTATAGACAACCATTTCCAGGACCAGGTTTGGCTATAAGGGTAATTGGT
GAAGTAAATGAAAATGATTTAAATATTTTAAGAGAAGCAGATGCAATAGTTTTAGAAGAAATAAAAAAAGCAGGACTTTA
TAAAGATTTATGGCAATCTTTTGCAGTTTTACTGCCAATTTATACAGTCGGAGTAATGGGTGATTATAGAACATACGAAA
AAGTCATAGCAATAAGAGCAGTAGAAAGTACGGACGGAATGACAGCTGACTGGGCAAGGCTACCGTATGATTTACTTGAC
ACGATGATGAGACGAATAATTAACGAAGTAAAAGGTGTCAATAGAGTAGTTTATGATATCTCTTCAAAGCCACCTGCAAC
CATAGAATGGGAATAA

Protein sequence :
MHRGIVILDFGSQYTQLIARRIRELNVYSEILPFNASVEEILKHNPKGIIFSGGPASVYEPDAPKPDEKVYDLGLPILGI
CYGLQLITHHFGGEVIKADKHEYGKAELEVLDHEDLFYNIPHYTQVWMSHADKVIKLPEGFEVIGRTFNAPFAAVRNKEK
KIWGVQFHPEVSHTLLGKEMLKNFAVRICKCKQDWTMGNFLMEKQVEIRKMVGDKKAICALSGGVDSSVAAVLVHNAIGD
NLTCIFVDNGLLRKGEREQVEKTFRDNFHISLIVVDAKDRFLKALKGITDPEQKRKIIGNLFIEVFEEEAKKLKDVEYLV
QGTLYPDVIESVSVKGPSAVIKTHHNVGGLPERMNLKLIEPLRELFKDEVRELGKELGLPEEIIYRQPFPGPGLAIRVIG
EVNENDLNILREADAIVLEEIKKAGLYKDLWQSFAVLLPIYTVGVMGDYRTYEKVIAIRAVESTDGMTADWARLPYDLLD
TMMRRIINEVKGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-149 59
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-149 59
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-149 58
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-129 53