Gene Information

Name : lysS (SYO3AOP1_1601)
Accession : YP_001931753.1
Strain : Sulfurihydrogenibium sp. YO3AOP1
Genome accession: NC_010730
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 1653690 - 1655423 bp
Length : 1734 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGCAGAAGGGATTTTAGAAAGCAGATTAGAAAAAATTAGAAAATTAACAGAAGAAGGAAAAAATCCTTACCCACATAA
ATTTAGCATTACAACAGACCTAAAATCTGTTAGAGAAGGACTTGAATTTGAGCCCGAAGATAAAGAGTACATCATAAAAG
GAAAAATAAAAAGGGTATCTAAAAAGGAAAACGATTATTTTATAAGATTTGAAGATTTAAACGGACATTACGAAATTCAA
GTAATCTTTCCACAAAAAGAAAAACTATCTCCAAATACAGTAGCATCATTCAAAGGAAAATTAAAAAGAATTGACGGAAA
GCTTACACTTTTAGCTGAAGAAGTTTTATTTGAAGAAGCAGGAGAAGATGTATCAACAATAAAAAATAGATATGACAAAG
ACCCGGAGAAAAAGCAAGTTGCAGTAGCCGGTAGGCTAATAGCACTCAGAGACCAAGGAAAAGCTGCTTTTGGACATATC
CAAGATTCGGACGGAAAACTGCAGGTATACTTTAACGCTGACATTCTTGGAGAAGAAAATTATAAAAAAGCAATGGACTT
AATAGATATTGGAGATATTATTGGCGTAGAAGGTCATCTATTTAGAACTATGACAGGTGAGCTTACAGTAGAAGTTCATA
ACTATGAAATATTAGCAAAATCTTTAAGACCACTTCCGGAAAAATGGCACGGACTAAAAGATACTGAGTACAGATACAGA
TACAGATACTTAGATTTAATAGCAAATCAAAGAACGAGAGAAATCTTTAAAATAAGGTCTAAGGCAATAAAAAGTTTGAG
AGAGTTTTTAGAAAGTAAAGGATTTATAGAAGTAGAAACGCCAATACTTCAACCTGTAGCATCAGGAGCTATGGCAAAAC
CTTTTATTACATATCACAACGCACTTGATATGAATCTGTATCTAAGAATTGCACCAGAGCTTTATTTGAAAATGCTTGTA
GTTGGTGGATTTAATAGAGTTTTTGAGATAGGAAGAAATTTCAGAAATGAAGGGATAGATACAACGCACAACCCAGAATT
TACGATGGTTGAGTTTTACGCAGCATACTTAGACTATAACGACTTGATGGCATTGACAGAAGAGCTGTTTAGAAAAATAC
TTCTTGATACAGTTGGAACGTTAAAAATAACATGGGAAGGCCAAGAGCTTGATTTTGAAAAACCATTTAGAAAAGTAGCA
TTTTTTGATGCATTAAAACAAAAAACAGGAAAAGATAAAGAATTTTTCTTAGATTTTGAAAAAGCAAGAAATTTTGCAAA
AGAGGTAGGAATACCAAAAGCAGATACATTAACCCATGTGAAAATTCTTGATAAACTTTTTGAACATTTTGTTGAAGAAG
ACCTTATCCAGCCTACATTTGTAATAGATTTTCCAAAGATACTATCACCACTTGCAAAAACACACAGAAACGACCCAGAT
TTAGTAGAAAGATTTGAGCTTATCATAAATAAAAAAGAGCTTGCAAACGCTTATACAGAGCTAAATGACCCTATGGACCA
AAGAGAAAGATTCATCCAACAAATCAGAGAAAAAGAGATGGGCGATGAGGAAGCAATGGACATTGATGAAACATTCTTAA
CAGCTTTAGAGTATGGTTTACCACCTACAGCAGGTGAAGGAATTGGAATAGACAGACTTGTAATGATGCTTACAGACAAT
TACTCAATCAGAGAAGTAATCCTATTTCCAACTCTTAGACCAGAAGGACAGTAA

Protein sequence :
MAEGILESRLEKIRKLTEEGKNPYPHKFSITTDLKSVREGLEFEPEDKEYIIKGKIKRVSKKENDYFIRFEDLNGHYEIQ
VIFPQKEKLSPNTVASFKGKLKRIDGKLTLLAEEVLFEEAGEDVSTIKNRYDKDPEKKQVAVAGRLIALRDQGKAAFGHI
QDSDGKLQVYFNADILGEENYKKAMDLIDIGDIIGVEGHLFRTMTGELTVEVHNYEILAKSLRPLPEKWHGLKDTEYRYR
YRYLDLIANQRTREIFKIRSKAIKSLREFLESKGFIEVETPILQPVASGAMAKPFITYHNALDMNLYLRIAPELYLKMLV
VGGFNRVFEIGRNFRNEGIDTTHNPEFTMVEFYAAYLDYNDLMALTEELFRKILLDTVGTLKITWEGQELDFEKPFRKVA
FFDALKQKTGKDKEFFLDFEKARNFAKEVGIPKADTLTHVKILDKLFEHFVEEDLIQPTFVIDFPKILSPLAKTHRNDPD
LVERFELIINKKELANAYTELNDPMDQRERFIQQIREKEMGDEEAMDIDETFLTALEYGLPPTAGEGIGIDRLVMMLTDN
YSIREVILFPTLRPEGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-102 49
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-83 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001931753.1 lysyl-tRNA synthetase VFG1668 Protein 1e-102 49