Gene Information

Name : leuS (PGN_0819)
Accession : YP_001928935.1
Strain : Porphyromonas gingivalis ATCC 33277
Genome accession: NC_010729
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 901712 - 904489 bp
Length : 2778 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGAATATAACTTTCAGGAAATAGAAAAGCGTGTGCAGGGACAGTGGCGCAAAGACAAGGTTTACCGCGTTGCGGAAGA
CACAAGTAAAAAACCTTTCTACGTGCTCGACATGTTTCCGTATCCTTCCGGAGCGGGACTGCATGTAGGGCATCCACTTG
GTTATATAGCTTCCGATATTTTTTCGCGCTATAAGCGTTTGCGTGGATTCAATGTATTGCATCCGATGGGATATGATGCA
TTCGGCCTACCTGCCGAACAATATGCCATCCAAACCGGCCAACACCCCGAAAAAACGACAGAAGAAAATACAGCTCGCTA
TCGCGAGCAACTGGACAAAATCGGCTTTTCGTACGATTGGGAACGCGAGATTCGCACTTGTGATCCGAATTATTATAAAT
GGACACAGTGGGCTTTCCTGAAAATGTTCGACTCGTACTACTGCAATCAAGCACAACAGGCACGACCGATAAGCGAGCTG
ATCGAAGTTTTTGCCCGACAAGGTAATGAAGGTCTCAACGTGGCATGCGGCGAAGGAGTCCGTTTCACGGCGGAGGAGTG
GACAGCCATGAGCGAAAAAGAACAACAAGAGATACTCATGAATTACCGTCTGGCTTATTTGGGCGACACGATGGTCAATT
GGTGTCCGGCCCTCGGTACCGTATTAGCTAACGATGAAGTCAAGGACGGAGTGAGCGAGCGTGGAGGACACCCCGTGGAG
CAAAAGAAGATGCGCCAGTGGTGCCTGCGCGTATCGGCCTATGCCGAGCGTTTGCTGCACGACCTTGAAACACTGGATTG
GACTGAATCGTTGAAAGAGACACAGCGCAACTGGATCGGACGATCCGAAGGAGCCGAAATGGAGTTTCGTCTGGCCGGTA
AGGATTGCACATTTACGATTTTTACTACCAGAGCCGACACGATATTCGGTGTCACGTTTATGGTGTTGGCTCCTGAGAGT
GAATTGGTTGAAGAGGTAACGACAGAGGAGCAGCGCGCTGCAGTGGAGACTTATCTGACAGAAACAAAGCGACGGACAGA
ACGTGAACGAATATCCGACAAACGAGTCTCAGGAGTTTTCTCCGGCAGTTATGCCATCAATCCTCTCACCGGTAAGGAAA
TTCCTATTTGGATCAGCGACTACGTATTGGCAGGATATGGCACAGGTGCTATTATGGCTGTGCCGGCTCATGATACGCGC
GACTTTGCCTTTGCACGCCATTTCGATCTCCCCATCGTCCAAGTCGTGGTACCCGAGGGCGAAACGGCTACCGATCCTGC
CACATGGGAGGATGCCAAAGACAGTAAGAGCGGTATAATGGTCAATTCCGATTTTCTGAATGGTCTCTCCGTAGAAGATG
CCATAGCCCAAACCAAGGAGTATATCAGAGAAAAACACTTAGGTTGCGTGAAAGTAAACTACCGCCTGCGCGATGCTATT
TTCAGTCGTCAGCGTTATTGGGGGGAACCTTTCCCCATCTACTACAAGGAGGGTATGCCTCACGCGCTGGATGAAGATCG
ACTGCCGCTCCGATTGCCGGAGGTAGATAAATTCCTCCCTACGGAAAGCGGTGAACCGCCCCTTGGAAGAGCTACCGGCT
GGCATACAGCCGAAGGTTATCCATACGAATTGAGCACAATGCCCGGATTTGCCGGTAGCAGTGCTTACTATCTGCGATAT
ATGGATCCACAAAACGATACTGCACTCGTCAGCCGATCGGCGAATGAATATTGGCGTCACGTTGATCTATACATCGGTGG
TACGGAGCACGCCACAGGACACCTGATTTATAGCCGCTTTTGGAACAAATTTCTCTTCGACCTCGGTATCGTATGCGAAG
CCGAACCTTTCCGCAAGCTGGTGAATCAGGGAATGATCCAAGGACGCTCCAACTTCGTCTATCGAATCAAGAATACCAAT
ACATTCGTCAGCTATGGACTGCGCGAGCAATATGAGGTGACTCCACTCCATGTAGATGTCAATATCGTATCGAACGATCA
GCTCGACATAGACCGCTTCCGTGCATGGCGTCCGGAGTACGCTTCGGCAGAGTTCATCCTTGAAGATGGCAAGTATATCT
GTGGATGGGCTATCGAGAAGATGAGCAAATCGATGTTCAACGTCGTCAATCCCGATGATATTATTGCTCGTTATGGAGCC
GATACCCTGCGACTCTACGAAATGTTCCTCGGACCGCTGGAGCAGAGCAAGCCTTGGGATACGAATGGTATCGATGGTGT
ACATCGCTTTTTGAAAAAGTTCTGGGCGTTGTACTACAATGCAGATGGTATACGCGTCACCGATACAGCACCGACAAAAG
AGGAGCTGAAGAGCCTGCACAAGCTCATCAAAAAGGTAGGACAGGATATTGAATCTTTTTCTTTCAACACTTCGATACCA
GCCTTCATGATTTGTGTGAATGAGCTGACAGCAGCCAAAACCACTTCTCGTGCCATACTATGTCCATTGCTGACAGTGCT
CTCTCCTTTTGCACCGCATATCACCGAGTGGCTATGGCAGGAACTGGGAGTAGAAGGCAGTATCGTAACTGCAACATGGC
CCGAATACAATGAAGAGTATCTGGTGGAGAGCTGTGTACGCTATCCGGTGAGCTTCAATGGCAAGGTTCGTTTCAATATC
GAACTGCCGGCTGATATGAGCAAAAAAGATGTAGAGCAAGCAGCCCTTACTGCTCCCGAAGCAGCCCGTTGGCTCGAAGG
CAAGAGTCCGAAAAAAGTCATTGTAGTCCCCGGGAGGATCGTCAATGTAGTTGTATGA

Protein sequence :
MEYNFQEIEKRVQGQWRKDKVYRVAEDTSKKPFYVLDMFPYPSGAGLHVGHPLGYIASDIFSRYKRLRGFNVLHPMGYDA
FGLPAEQYAIQTGQHPEKTTEENTARYREQLDKIGFSYDWEREIRTCDPNYYKWTQWAFLKMFDSYYCNQAQQARPISEL
IEVFARQGNEGLNVACGEGVRFTAEEWTAMSEKEQQEILMNYRLAYLGDTMVNWCPALGTVLANDEVKDGVSERGGHPVE
QKKMRQWCLRVSAYAERLLHDLETLDWTESLKETQRNWIGRSEGAEMEFRLAGKDCTFTIFTTRADTIFGVTFMVLAPES
ELVEEVTTEEQRAAVETYLTETKRRTERERISDKRVSGVFSGSYAINPLTGKEIPIWISDYVLAGYGTGAIMAVPAHDTR
DFAFARHFDLPIVQVVVPEGETATDPATWEDAKDSKSGIMVNSDFLNGLSVEDAIAQTKEYIREKHLGCVKVNYRLRDAI
FSRQRYWGEPFPIYYKEGMPHALDEDRLPLRLPEVDKFLPTESGEPPLGRATGWHTAEGYPYELSTMPGFAGSSAYYLRY
MDPQNDTALVSRSANEYWRHVDLYIGGTEHATGHLIYSRFWNKFLFDLGIVCEAEPFRKLVNQGMIQGRSNFVYRIKNTN
TFVSYGLREQYEVTPLHVDVNIVSNDQLDIDRFRAWRPEYASAEFILEDGKYICGWAIEKMSKSMFNVVNPDDIIARYGA
DTLRLYEMFLGPLEQSKPWDTNGIDGVHRFLKKFWALYYNADGIRVTDTAPTKEELKSLHKLIKKVGQDIESFSFNTSIP
AFMICVNELTAAKTTSRAILCPLLTVLSPFAPHITEWLWQELGVEGSIVTATWPEYNEEYLVESCVRYPVSFNGKVRFNI
ELPADMSKKDVEQAALTAPEAARWLEGKSPKKVIVVPGRIVNVVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 5e-119 43