Gene Information

Name : PGN_0613 (PGN_0613)
Accession : YP_001928729.1
Strain : Porphyromonas gingivalis ATCC 33277
Genome accession: NC_010729
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 669767 - 671074 bp
Length : 1308 bp
Strand : -
Note : GTG, PG1277; similar to gb|AAQ66357.1, percent identity 98.6 in 421 aa, BLASTP E(): 0; may be inner membrane protein

DNA sequence :
ATGAAACCATATAAGGCATTGACAATAATCAATACGAAAGAGATGAATAACATTAGGATTGCTATCATCGGTTTGGGATA
TGTGGGTCTCCCTTTAGCTCGTCTGTTTTCCACAAAATTTCCGACAATCGGCTTCGACATCAACCCGAACCGTGTAGAAG
AACTAATATCAGGATATGACAGCACGGGGGAAATTGGAAATGAATTATTACAGGAAGCCTTGCAAAAGGGGTTACTTTGT
ACAACAAAAATTGAAGAGATTAGGGATTGTAACTTCTATATCGTGACAGTTCCTACCCCTATAGATCACAATCACACCCC
GGACTTACGGCCACTTTTGGCAGCCAGCGAAACAATCGGAAAGGTAATCGACCAAGGAGATGTGGTGGTGTACGAAAGTA
CGGTGTATCCCGGTGTAACAGAAGACGAATGTATTCCGATTATCGAGAAAGTTTCGGGTCTCAAATACAATGTGGACTTC
TTTGCCGGATACAGTCCCGAACGAATCAATCCGGGAGATAAAGTTTACACAGTAGAGAATATAAAAAAAGTGACATCCGG
TTCTACTCCGGAAATAGCCGACTATGTGGATAGAATGTATAATACCGTGTTGGTCAATGGCACACACAAAGCATCTTCCA
TAAAAGTTGCAGAGGCTTCAAAAATCATAGAAAATGCCCAACGAGATGTAAACATTGCGTTTATGAACGAAATTGCGAAG
ATTTTCAATGCAATGGAAATTGATACGCGCGAAGTATTGGAGGCTGCAGCTACAAAATGGAACTTCCTACCTTTTCAGCC
GGGCTTGGTCGGTGGGCATTGTATAGGGGTAGATCCCTATTACCTTATTCAACGAGCACAGGTATATGGAGTTTATCCTC
GGGTATTGATGTCTGCGAGAAGGCTGAATGACAGCATGGGCTCCTATATAGCCTCGCAAACCATCAAGCAAATGAATAAA
GCAGGCATCATGGTGAAAGATGCACGAATTCTGATTTTAGGATTTACATTCAAAGAAAACTGTCCGGATATCCGCAATAC
CAAAGTGATAGACACGTACAGCACCCTGCAAGAATACACGAAGAATATTATAGTACACGATCCTTGGGCAAATCCTTCTA
TCGCTGAGCAAGTATATGGCATAAAGATTCACAATGAATTCCCTAAAGGAAAATTCGATGCCATTATTATTGCTGTAGCG
CATAGAGATTTTTCGAATATCGATCTCGAAAAATCATCCACAGCCAACACCATTATCTACGATGTGAAGGGCATTCTACC
CCAAGGGAAAAAGTATCACAAACTGTAG

Protein sequence :
MKPYKALTIINTKEMNNIRIAIIGLGYVGLPLARLFSTKFPTIGFDINPNRVEELISGYDSTGEIGNELLQEALQKGLLC
TTKIEEIRDCNFYIVTVPTPIDHNHTPDLRPLLAASETIGKVIDQGDVVVYESTVYPGVTEDECIPIIEKVSGLKYNVDF
FAGYSPERINPGDKVYTVENIKKVTSGSTPEIADYVDRMYNTVLVNGTHKASSIKVAEASKIIENAQRDVNIAFMNEIAK
IFNAMEIDTREVLEAAATKWNFLPFQPGLVGGHCIGVDPYYLIQRAQVYGVYPRVLMSARRLNDSMGSYIASQTIKQMNK
AGIMVKDARILILGFTFKENCPDIRNTKVIDTYSTLQEYTKNIIVHDPWANPSIAEQVYGIKIHNEFPKGKFDAIIIAVA
HRDFSNIDLEKSSTANTIIYDVKGILPQGKKYHKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 5e-106 54
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 5e-106 54
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 4e-101 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PGN_0613 YP_001928729.1 UDP-glucose 6-dehydrogenase VFG0431 Protein 2e-106 54