Gene Information

Name : PGN_1750 (PGN_1750)
Accession : YP_001929866.1
Strain : Porphyromonas gingivalis ATCC 33277
Genome accession: NC_010729
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1963462 - 1964226 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAATACAGAGGTAATAGCCATCATTCCGGCTCGATTTGCTTCCAGCCGATTCCCGGGCAAGCCACTGGCCGATATGCT
TGGCAAGTCTATGATCCAACGGGTACATGAGCGAATAGCTGGTGTCGTCCCCCGGGCCGTCGTAGCCACCGATGACGAAC
GTATCCGTCAGGCCGTGGAGGACTTCGGAGGAGAGGTGGTGATGACGTCCCCAGAGTGCAGTAGTGGTACAGAACGCTGT
CGGGAAGCATTCGACAAAGTAGGTCGGGGAGAAAAGATCGTCCTGAATCTGCAAGGCGATGAACCTTTTATCCAAAAGGA
ACAGATCGATCTGCTGATTTCGGCCTTCGACAAACCAGAAACCGATATAGCTACGTTAGCAGAAGTTTTCTCGTCTGACG
CAAGCTTCGAGCGATTGAACAATCCAAACAGCCCGAAGATCGTATTGGATCATGGAGGCTATGCCCTTTATTTCAGCCGC
TCCGTTATCCCATATCTCAGGGGGGTACAGCCTGACTCTTGGTGCCGTCGGCATACTTACTACAAGCATATCGGGATCTA
TGCCTTTCGCCCGACCGTCCTCCGCAAGATAACCTCACTGCCACAAAGTACGGCAGAGCAAGCCGAAAGCCTCGAACAGC
TTCGCTGGCTGGAATACGGCTATCGGATTCGAGTGCTGCAAACACAGCAGAGTACGATAGGAATCGATACGCCGGAGGAT
ATGGACAAGGCCATAGCCTATCTCCGTTCGCAGGGAATGGAATGA

Protein sequence : 
MNTEVIAIIPARFASSRFPGKPLADMLGKSMIQRVHERIAGVVPRAVVATDDERIRQAVEDFGGEVVMTSPECSSGTERC
REAFDKVGRGEKIVLNLQGDEPFIQKEQIDLLISAFDKPETDIATLAEVFSSDASFERLNNPNSPKIVLDHGGYALYFSR
SVIPYLRGVQPDSWCRRHTYYKHIGIYAFRPTVLRKITSLPQSTAEQAESLEQLRWLEYGYRIRVLQTQQSTIGIDTPED
MDKAIAYLRSQGME

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-38 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 3e-38 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-38 44