Gene Information

Name : PGN_1646 (PGN_1646)
Accession : YP_001929762.1
Strain : Porphyromonas gingivalis ATCC 33277
Genome accession: NC_010729
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 1843456 - 1844727 bp
Length : 1272 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGACACTCAAGCAAATCATAGAAAATAAGGAAGAAGTGATCCGTCGCTTGGCGGTGAAGCACTTCGATGCAGCTGC
TATTCTCGACGAAGTCATCTCTCTCGACAGACAGCGACGCGAAACTCAACAGAGTCTGGATGCTCGTTTGGCGGAGCAAA
ACGCCATTGCCAAGGAGATCGGAGCTTTGATGAAAGCCGGCAAGAAAGGCGAGGCAGAGGCCATCCGTACGAAAGTAGCC
GATATGAAAGCCGAGAGCCACCATCTGGAAGAGCGGAAAGCTGATCTGGAGAATGCTATACGCCAACAGCTTCTGCTTAT
CCCGAATCTGCCGCATGAGTCTGTCCCTGCAGGCAAGACCGCAGAGGAGAATGTCTGTGTGAAGACAGGCGGCACAGTGC
CGGAGCTTGGAACGCACAAGCTCCCACATTGGGATCTGGCCAAGAAATACGATCTGATCGACTTCGAACTCGGCGTCAAG
ATAACCGGAGCAGGCTTCCCTGTCTATAAGGGCAAAGGAGCACGCCTGCAGCGAGCTTTGGTCAACTTCTTCTTGGACGA
AGCCCGCAACGCCGGCTTCACGGAGATAGAGCCGCCCTATGTGGTCAATGAAGATTCCGGCTATGGTACGGGACAGCTCC
CCGACAAGGAAGGGCAGATGTACCATGTCACGGCGGACAACCTGTATCTGATCCCCACGGCAGAGGTGCCGGTGACCAAT
ATCTTCCGCGATGTCATTCTCTCCGAGGACGAATTGCCCATTCTCCTGACCGCTTACTCGGCTTGCTTCCGACGCGAAGC
CGGTTCGTATGGCAAGGATGTTCGCGGCCTGAACCGCCTCCATCAGTTCAACAAGGTGGAGATCGTCTGCATCGACAAGC
CCGAACACTCCTACGAACAGCTCGATCAGATGGTCGGCTATGTCCAAGGCCTTGTAGATAAGTTGGGACTTCCGTGGCGT
ATCCTTCGCCTCTGCGGCGGAGATATCAGCTTCACTTCGGCATTGACTTACGACTTCGAAGTCTATTCGGCTGCCCAAGA
GCGGTGGTTGGAGGTTAGCTCGGTGTCCAATTTCGAGAGCTTCCAAGCCAATCGTCTGAAGTGCCGTTATCGCAATGCGG
ATAAGAAAGTGGAGCTTTGCCACACGCTCAACGGTAGTGCCTTGGCCTTGCCGCGTATCGTGGCTGCTCTGTTGGAAAAC
AATCAGACAGCCGATGGCATCCGCATCCCCGACTGTCTGGTACCTTATACAGGCTTCTCGATGATCGATTGA

Protein sequence :
MLTLKQIIENKEEVIRRLAVKHFDAAAILDEVISLDRQRRETQQSLDARLAEQNAIAKEIGALMKAGKKGEAEAIRTKVA
DMKAESHHLEERKADLENAIRQQLLLIPNLPHESVPAGKTAEENVCVKTGGTVPELGTHKLPHWDLAKKYDLIDFELGVK
ITGAGFPVYKGKGARLQRALVNFFLDEARNAGFTEIEPPYVVNEDSGYGTGQLPDKEGQMYHVTADNLYLIPTAEVPVTN
IFRDVILSEDELPILLTAYSACFRREAGSYGKDVRGLNRLHQFNKVEIVCIDKPEHSYEQLDQMVGYVQGLVDKLGLPWR
ILRLCGGDISFTSALTYDFEVYSAAQERWLEVSSVSNFESFQANRLKCRYRNADKKVELCHTLNGSALALPRIVAALLEN
NQTADGIRIPDCLVPYTGFSMID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-73 45