Gene Information

Name : PGN_0160 (PGN_0160)
Accession : YP_001928276.1
Strain : Porphyromonas gingivalis ATCC 33277
Genome accession: NC_010729
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 174260 - 176023 bp
Length : 1764 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAAAGAATTCAAAGTGACTACCGGCCCTCTGCCCGGCAGTGAGAAAATCTATGTCGAAGGAGAGCGTTTTCCCTTCCT
GCGTGTACCGATGCGGCGCATCCGAATGTCCGATACCATATTGGAGAACGGCGAACGTGAGAAAAACGAAGATGTAGTCG
TATACGATACCAGCGGCCCCTATACCGATACCTCCTATGAGGTGAATCTGCACCGAGGCGTACCGAAGATACGCGAGCAG
TGGATAGAGGATCGGGGCGATACGCTGCGGCTCGAAGGGCTCAGCTCCGAATACGGACGGATGAGGCAGTCGGACGCTTC
GCTCGAAGAGCTGCGCTACGAGCATGTATGCACACGTCCCCGTGCCGCCAAGGACGGCTGTGCCACGCAGCTCTACTACG
CCCGTCAGGGGATCGTGACGCCGGAGATGGAGTTCGTGGCCATCCGCGAAAATCAGTTGATCGATCAGGTCAGGACGCGC
TATCGCGCCGAGGAGGGTGAGCCGCTCGGAGCTGTTATCCCGCGCAAGATCACACCCGAATTTGTACGCGACGAGATTGC
CGCCGGACGGGCTATCCTTCCGGCCAATATCAATCATCCGGAGAGTGAGCCGATGATCATTGGGCGTAATTTCCTCGTCA
AGATCAATGCGAACATAGGCAATTCGCCCATCAGCAGTACCATCGAGGAGGAGGTGGAAAAGGCCGTCTGGGCCATACGC
TGGGGTGCCGATACGGTCATGGATCTCTCCACGGGGGATCATATCCATGAGACGCGCGAGTGGATCATCCGCAATTCACC
CGTGCCCATCGGCACCGTACCTCTCTACCAGACGCTGGAGAAGGTGCAGGGCGATGTGACGAAGCTCAACTGGGAGATAT
TCCGCGATACGCTCATCGAGCAGGCTGAGCAGGGTGTGGACTACTTCACCATCCACGCCGGTCTGCGTTGGCACCACGTG
CCTCTGACCTTGCGCCGTCTCACGGGGATCGTCTCCCGCGGTGGTTCCATCATCGCCAACTGGTGCACCACCCACAAGCG
CGAAAGTTTCATCTACGAGCATTTCGAAGAGATCTGCCGGATCCTCGCACACTACGACGTAGCCATATCCCTCGGCGATG
GCTTGCGCCCGGGCTGCATCCACGATGCCAACGATGCTGCGCAGATAGCTGAGCTGAAGACACTGGGCGAACTTACCGAG
ATCGCTTGGAAGTACAACGTGCAAACCATTATCGAAGGCCCGGGACACGTGCCCATGCACAAGATCCGCGAGAATATGGA
GATTCAGCTCGAAGCCTGCCATGGCGCACCCTTCTACACCCTCGGCCCGTTGGTCAGCGACGTGGCGTCCGGCTACGACC
ATATCACATCGGCCATCGGCGCGGCACAGATCGGATGGTTCGGCACAGCCATGCTCTGCTATGTGACGCAAAAGGAGCAT
TTGGGTCTGCCCAACCGCGAAGATGTACGTGAAGGTGTAGTAACCTATAAACTGGCTGCTCATGCCGCCGACTTGGCCAA
AGGACACCCCACGGCGTACTGGCGCGACTATATGATGAGCAAGGCGCGGTTCGAATTCCGCTGGAAGGATCAGTTCCATC
TCTCGCTTGATCCGGAGAAAGCGATCCAATTCCACGATGCCACGCTGCCGGACGAAGGCCACAAAGAGGCGCATTTCTGC
TCCATGTGCGGCGAACACTTCTGCTCCATGCGTGCCAATAAGAACTTCCGCAAGTTGCTAAACGAAGAGGCAGTCTCCAA
ATGA

Protein sequence :
MKEFKVTTGPLPGSEKIYVEGERFPFLRVPMRRIRMSDTILENGEREKNEDVVVYDTSGPYTDTSYEVNLHRGVPKIREQ
WIEDRGDTLRLEGLSSEYGRMRQSDASLEELRYEHVCTRPRAAKDGCATQLYYARQGIVTPEMEFVAIRENQLIDQVRTR
YRAEEGEPLGAVIPRKITPEFVRDEIAAGRAILPANINHPESEPMIIGRNFLVKINANIGNSPISSTIEEEVEKAVWAIR
WGADTVMDLSTGDHIHETREWIIRNSPVPIGTVPLYQTLEKVQGDVTKLNWEIFRDTLIEQAEQGVDYFTIHAGLRWHHV
PLTLRRLTGIVSRGGSIIANWCTTHKRESFIYEHFEEICRILAHYDVAISLGDGLRPGCIHDANDAAQIAELKTLGELTE
IAWKYNVQTIIEGPGHVPMHKIRENMEIQLEACHGAPFYTLGPLVSDVASGYDHITSAIGAAQIGWFGTAMLCYVTQKEH
LGLPNREDVREGVVTYKLAAHAADLAKGHPTAYWRDYMMSKARFEFRWKDQFHLSLDPEKAIQFHDATLPDEGHKEAHFC
SMCGEHFCSMRANKNFRKLLNEEAVSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 65
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 65
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-180 64