Gene Information

Name : PGN_1618 (PGN_1618)
Accession : YP_001929734.1
Strain : Porphyromonas gingivalis ATCC 33277
Genome accession: NC_010729
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1809862 - 1811061 bp
Length : 1200 bp
Strand : +
Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine

DNA sequence :
ATGAAAAAAGAAGACCTTATGCGTAGTGGCTTTGCCACACGTGCCATCCATGGAGGCGCTATCGAGAACGCCTTCGGCTG
CTTAGCCACTCCCATCTACCAAACATCGACTTTCGTTTTTGACACTGCCGAACAGGGAGGCCGCCGCTTTGCCGGAGAGG
AAGACGGATACATCTATACCCGTCTGGGCAACCCCAACTGCACCCAAGTGGAAGAGAAACTGGCCATGCTCGAGGGCGGA
GAAGCCGCCGCATCGGCCTCATCCGGTATCGGAGCCATCAGCTCTGCCATCTGGGTATGCGTGAAGGCCGGCGACCATAT
CGTAGCCGGCAAGACGCTCTACGGCTGCACCTTCGCCTTCCTCACCCACGGACTGAGCCGCTACGGTGTGGAAGTCACCC
TCGTGGATACCCGCCATCCGGAAGAGGTGGAGGCTGCCATTCGCCCGAATACGAAGCTCGTCTATCTGGAGACTCCGGCC
AACCCCAATATGTACCTGACCGACATCAAGGCAGTCTGCGACATCGCTCATAAGCACGAAGGCGTACGCGTCATGGTGGA
CAATACCTACTGCACGCCCTATATCTGCCGTCCGCTGGAGCTGGGTGCCGACATCGTGGTACACAGCGCGACCAAGTACC
TGAACGGACATGGCGACGTCATCGCCGGATTCGTCGTTGGTAAAGAGGACTACATCAAGGAGGTGAAGCTCGTCGGCGTC
AAGGACCTCACGGGGGCCAATATGAGTCCGTTCGATGCTTATCTGATCAGCCGCGGCATGAAGACGCTGCAGATACGTAT
GGAGCAGCACTGCCGCAATGCTCAGACCGTAGCCGAATTCCTCGAAAAGCATCCGGCCGTAGAAGCAGTTTATTTCCCCG
GACTTCCGAGCTTCCCCCAATACGAATTGGCCAAGAAGCAGATGGCACTGCCCGGAGCCATGATCGCCTTCGAAGTGAAG
GGCGGTTGCGAAGCCGGTAAGAAGCTGATGAACAACCTGCACCTCTGCTCCCTCGCCGTGAGCTTGGGCGATACGGAAAC
CCTCATCCAGCATCCGGCCAGCATGACCCACTCGCCCTACACACCCGAAGAGCGTGCTGCCAGCGACATATCCGAAGGAC
TGGTACGCCTGTCCGTGGGTCTGGAGAACGTGGAGGACATCATCGCCGACCTCAAACACGGTCTGGACAGCCTGATCTAA

Protein sequence :
MKKEDLMRSGFATRAIHGGAIENAFGCLATPIYQTSTFVFDTAEQGGRRFAGEEDGYIYTRLGNPNCTQVEEKLAMLEGG
EAAASASSGIGAISSAIWVCVKAGDHIVAGKTLYGCTFAFLTHGLSRYGVEVTLVDTRHPEEVEAAIRPNTKLVYLETPA
NPNMYLTDIKAVCDIAHKHEGVRVMVDNTYCTPYICRPLELGADIVVHSATKYLNGHGDVIAGFVVGKEDYIKEVKLVGV
KDLTGANMSPFDAYLISRGMKTLQIRMEQHCRNAQTVAEFLEKHPAVEAVYFPGLPSFPQYELAKKQMALPGAMIAFEVK
GGCEAGKKLMNNLHLCSLAVSLGDTETLIQHPASMTHSPYTPEERAASDISEGLVRLSVGLENVEDIIADLKHGLDSLI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-63 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-64 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PGN_1618 YP_001929734.1 methionine gamma-lyase BAC0207 Protein 2e-102 57