Gene Information

Name : clpC (PGN_0008)
Accession : YP_001928124.1
Strain : Porphyromonas gingivalis ATCC 33277
Genome accession: NC_010729
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 7400 - 9979 bp
Length : 2580 bp
Strand : +
Note : GTT, PG0010; similar to gb|AAQ65268.1, percent identity 99.8 in 859 aa, BLASTP E(): 0; may be inner membrane protein

DNA sequence :
ATGGCATACGACTTTACACAAACATTCCGCAACAGCCTGGAGTACAGCTATCAGGAAGCAACCCGTCTCGGCGTCGTAGC
CGTGACGCAGGATATGCTCGTACTCGGTATCATTCGCGACGGAGACAATGGCGCGATCGACATCATGCGGCACTATGGGA
TCAACTTGTACGAACTCAAACGGTTGATCGAGTTGGAAGCCATCGCCGAGAGTTTGCCTGCTTCGCCTGAGGGATTGCCC
ATCTTCACCCCTTCGGCTCGGGAGGCTATCGATGATGCCACAGACATCTGTGCCGACATGGAGGACGAGGCCGTCAGCCC
GGTCCATCTGTTGCTGAGTATCCTCAACTCGACACAGGAGAGCTTAGTACAAAAGATATTTATGAAACAAGGTATAAAAT
ACGACACCATCCTGTCGGATTACTTCGGACAGCGCAACCCCTCCGAAGGGAAGTCTCCCTCCGAAATGGAGATCCTCGAC
GGGTACCAAGACAACGACTTCGACGACGAAGAGGACGAATCCTCTCCGCCTTCCGGAAATAGCGGGACAGGCGGAGGCTC
CGGCGACGCCCCCGAACAGAATACCGGCGGAGGTGATACTACCACCACGACACGGAGTGGAGGCGACACGCCTGCACTGG
ACACCTTCGGCACCGACATCACTGCCATGGCGGCAGCAGGCAAGCTCGACCCGGTAGTGGGTCGGGAGCAGGAGATCGAA
AGGGTGATACAGATACTCAGCCGGCGCAAAAAGAACAATCCGGTGCTCATCGGCGAACCCGGTGTGGGCAAGAGTGCCAT
CGTGGAAGGACTGGCCGAACGCATCGTGAACAGGAAGGTGAGCCGTATTCTTTTCGACAAGCGGATCATCAGCCTCGATT
TGGCTCAGATGGTAGCCGGCACCAAATATCGCGGACAGTTCGAAGAGCGGTTGAAAGCCGTGCTCGACGAGCTGAAGAAG
AATCCGCAGATCATCCTCTTCATCGACGAGATACATACCATCGTGGGAGCAGGCTCTGCAGCCGGATCGATGGATACGGC
CAATATGCTCAAACCCGCTCTTGCCCGTGGACAGGTACAGTGCATCGGAGCCACTACGCTGGATGAGTATCGTAAGAACA
TAGAAAAGGACGGAGCACTCGAACGCCGCTTCCAGAAGGTGCCGATAGCCCCCTCGACTGCAGAAGAAACGCTGACCATC
CTGCAAAACATCAAAGAGAAATACGAGGACTATCACGGTGTACGCTATACGGACGAAGCGATCAAAGCGGCAGTGGAACT
GACCGATCGCTATGTATCCGATCGCTTCTTCCCCGATAAGGCAATAGATGCCATGGACGAGGCCGGCGCGAGCGTCCATA
TCACCAATGTGGTGGCTCCGAAAGAAATCGAGATACTGGAGGCCGAATTGGCATCGGTGCGAGAGAACAAGCTCTCGGCC
GTAAAGGCTCAGAACTACGAGCTGGCTGCCTCCTTCCGCGATCAGGAGCGGCGCACTCAGCAGCAGATAGCGGAAGAGAA
GAAAAAATGGGAAGAGCAGATGTCCAAGCACCGCGAGACGGTGGACGAGAATGTAGTGGCGCACGTAGTGGCGTTGATGA
CAGGCGTTCCGGCTGAGCGGCTGAGCACGGGCGAAGGCGAACGTCTGCGCACGATGGCAGATGATCTCAAGACCAAAGTA
GTAGGTCAGGACACAGCCATCGAAAAGATGGTGCGTGCCATCCAGCGCAATCGTCTGGGACTTCGCAATGAAAAGAAACC
GATCGGTTCTTTCCTTTTCCTCGGCCCCACGGGGGTAGGCAAGACCTATTTGGCCAAGAAGCTCGCCGAATACCTGTTCG
AGGATGAGAATGCCATGATCAGGGTGGATATGAGCGAGTATATGGAGAAGTTCTCCGTATCGCGTCTCGTGGGTGCCCCT
CCGGGATATGTGGGCTATGAAGAAGGCGGCCAACTGACGGAGCGCGTAAGACGCAAACCCTATTCCGTAGTTCTCTTGGA
TGAGATCGAAAAGGCGCATGCCGATGTCTTCAATCTGCTCTTACAGGTGATGGACGAAGGTCAGCTGACCGACAGTCTGG
GACGGCGCGTGAATTTCAAGAACACCGTGATCATCATCACCTCCAATGTGGGTACACGCCAGCTCAAAGACTTCGGGCAG
GGTATCGGGTTCCGTTCGGAAAAAGACGAGGAAGCGAACAAGGAGCATAGCCGTTCCGTGATCCAAAAAGCTCTGAACAA
GACGTTCAGCCCCGAATTTCTCAACCGTTTGGACGATATCATCCTCTTCGACCAACTGGGCAAGACGGAGATTCGCCGGA
TGGTGGACATAGAGCTTAAAGCCGTCTTGGCGCGCATCCATCGTGCCGGATACGACCTCGTCCTTACCGATGAAGCCAAG
GATGTGATAGCGACGAAGGGATACGACCTCCAATACGGAGCACGACCGCTCAAGCGCACACTCCAGAACGAAGTGGAGGA
TCGCCTCACGGATCTTATCCTCTCCGGACAGATCGAGAAAGGGCAGACGCTTACGCTCTCTGCTCGCGATGGCGAGATCA
TCGTACAAGAACAAGCATAA

Protein sequence :
MAYDFTQTFRNSLEYSYQEATRLGVVAVTQDMLVLGIIRDGDNGAIDIMRHYGINLYELKRLIELEAIAESLPASPEGLP
IFTPSAREAIDDATDICADMEDEAVSPVHLLLSILNSTQESLVQKIFMKQGIKYDTILSDYFGQRNPSEGKSPSEMEILD
GYQDNDFDDEEDESSPPSGNSGTGGGSGDAPEQNTGGGDTTTTTRSGGDTPALDTFGTDITAMAAAGKLDPVVGREQEIE
RVIQILSRRKKNNPVLIGEPGVGKSAIVEGLAERIVNRKVSRILFDKRIISLDLAQMVAGTKYRGQFEERLKAVLDELKK
NPQIILFIDEIHTIVGAGSAAGSMDTANMLKPALARGQVQCIGATTLDEYRKNIEKDGALERRFQKVPIAPSTAEETLTI
LQNIKEKYEDYHGVRYTDEAIKAAVELTDRYVSDRFFPDKAIDAMDEAGASVHITNVVAPKEIEILEAELASVRENKLSA
VKAQNYELAASFRDQERRTQQQIAEEKKKWEEQMSKHRETVDENVVAHVVALMTGVPAERLSTGEGERLRTMADDLKTKV
VGQDTAIEKMVRAIQRNRLGLRNEKKPIGSFLFLGPTGVGKTYLAKKLAEYLFEDENAMIRVDMSEYMEKFSVSRLVGAP
PGYVGYEEGGQLTERVRRKPYSVVLLDEIEKAHADVFNLLLQVMDEGQLTDSLGRRVNFKNTVIIITSNVGTRQLKDFGQ
GIGFRSEKDEEANKEHSRSVIQKALNKTFSPEFLNRLDDIILFDQLGKTEIRRMVDIELKAVLARIHRAGYDLVLTDEAK
DVIATKGYDLQYGARPLKRTLQNEVEDRLTDLILSGQIEKGQTLTLSARDGEIIVQEQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 6e-166 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_001928124.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0079 Protein 6e-177 54
clpC YP_001928124.1 ATP-dependent Clp protease ATP-binding subunit ClpC VFG0080 Protein 1e-148 49