Gene Information

Name : guaA (Mpop_3113)
Accession : YP_001925801.1
Strain : Methylobacterium populi BJ001
Genome accession: NC_010725
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3344737 - 3346302 bp
Length : 1566 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCATCGACACGTCCCACCACGACAAGATCCTGATCGTCGATTTCGGCTCCCAGGTGACTCAGCTCATCGCCCGCCG
CGTGCGCGAGGAGGGCGTCTATTGCGAGATCGTGCCCTTCACGAAGGCGGACGCCGCCTTCGACGAGCACCGGCCCAAGG
GCGTGATCCTATCGGGCGGCCCGGAATCGGTGACGACGGACCTGTCCCCGCGCGCGCCGCAAAAAATCTTCGAATCCGGC
GTGCCGGTCTTCGGCATCTGCTACGGCCAGCAGACCATGGCGGCCCAGCTCGGCGGCGAGGTCGAGGGCGGCCACCATGC
CGAGTTCGGCCGGGCCGAGGTCGAGATCGTGTCCGACTCGCCGCTGTTCCGGGGCATCTGGCATCCGGGCGAGAAGTACC
CGGTCTGGATGAGCCACGGCGACCGGGTCACCAAGCTGCCGGAGGGCTTCGCCACCATCGCGATGTCGCGCAATGCGCCC
TTCGCGGCCGTCGCGGATGAAGCGCGGAAATACTACGCCGTCCAGTTCCACCCGGAGGTGCATCACACCCCGCACGGCGC
CCTGCTGATCCGCAATTTCGTGCGCGACATCGCCGGCTGCTCCGGCGACTGGACCATGGGGACCTACCGCGAGGAGGCGA
TCGCCAAGATCCGCGAGCAGGTCGGCACCGAGAAGGTGATCTGCGGCCTGTCGGGCGGTGTCGATTCCTCGGTCGCGGCG
GTGCTGATCCACGAGGCGATCGGCGACCAGCTCACCTGCGTCTTCGTCGATCACGGCTTGATGCGCCTCGGCGAAGGCGA
AGAGGTGGTCCGCCTGTTCCGCGACCACTACAACATCCCCCTCGTCCACGTTGAGGCGCAGGACCTGTTCATCGGTGCGC
TCGAAGGGGTCGACGACCCCGAGGTGAAGCGCAAGACGATCGGCCGCCTGTTCATCGACGTGTTCGAGGCCGAGGCCAAG
AAGATCGGCGGCGCCGCCTTCCTCGCCCAGGGCACACTCTACCCGGACGTGATCGAGAGCGTCTCGTTCTCCGGCGGTCC
CTCGGTGACGATCAAGAGCCACCACAATGTCGGCGGCCTGCCCGAGCGCATGAACATGCGCCTCGTCGAGCCCCTGCGGG
AGCTGTTCAAGGACGAGGTGCGGCTGCTCGGCAAGGAACTCGGCCTGCCCGAAGCCTTCGTCGGCCGCCATCCCTTCCCC
GGTCCCGGCCTCGCGATCCGCTGCCCCGGGATCATCACCCGCGAGAAGCTCGAGGCCCTGCGCAAGGCCGACGCGATCTA
TCTCGACGAGATCCGCCAAGCCGGGCTCTACGACACGATCTGGCAGGCGTTTGCGGTGATCCTGCCGGTGAAGACGGTGG
GCGTGATGGGCGACGGGCGCACCTATGACCACGTCTGCGCGCTGCGCGCCGTCACCTCGGTCGACGGCATGACTGCCGAC
TTCTACCCGTTCGACATGGCCTTCCTCGGCCGGGTCGCCACACGGATCATCAACGAGGTGAAGGGCATCAACCGGGTGAC
CTACGACATCACCTCGAAGCCGCCCGGCACGATCGAGTGGGAATGA

Protein sequence :
MTIDTSHHDKILIVDFGSQVTQLIARRVREEGVYCEIVPFTKADAAFDEHRPKGVILSGGPESVTTDLSPRAPQKIFESG
VPVFGICYGQQTMAAQLGGEVEGGHHAEFGRAEVEIVSDSPLFRGIWHPGEKYPVWMSHGDRVTKLPEGFATIAMSRNAP
FAAVADEARKYYAVQFHPEVHHTPHGALLIRNFVRDIAGCSGDWTMGTYREEAIAKIREQVGTEKVICGLSGGVDSSVAA
VLIHEAIGDQLTCVFVDHGLMRLGEGEEVVRLFRDHYNIPLVHVEAQDLFIGALEGVDDPEVKRKTIGRLFIDVFEAEAK
KIGGAAFLAQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPERMNMRLVEPLRELFKDEVRLLGKELGLPEAFVGRHPFP
GPGLAIRCPGIITREKLEALRKADAIYLDEIRQAGLYDTIWQAFAVILPVKTVGVMGDGRTYDHVCALRAVTSVDGMTAD
FYPFDMAFLGRVATRIINEVKGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-129 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-129 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-130 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-116 51