Gene Information

Name : Mpop_2781 (Mpop_2781)
Accession : YP_001925471.1
Strain : Methylobacterium populi BJ001
Genome accession: NC_010725
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 2984028 - 2984528 bp
Length : 501 bp
Strand : -
Note : PFAM: dihydrofolate reductase region; KEGG: mex:Mext_2659 dihydrofolate reductase

DNA sequence :
ATGGGGCAACCGCGCGTCTCCCTGATCGCGGCCGTCGCCCGCAACGGCGTGATCGGCCGCGACAACGATCTCGTCTGGCG
GATCTCCAGCGACCTGAAGCGCTTCAAGGCGCTCACCATGGGCAAGCCGATCCTCATGGGCCGCAAGACCTGGGACTCGA
TCGGTCGCCCGCTGCCCGGCCGCCGCAGCCTCGTCCTCACCCGCGACCGCGCCCTGACCCTTTCGGACGTGACCATCGTG
CACGACTGGGACGAGGCGCTCGCCGCGGCCGGAGGTGACGAGTTGATGGTGGTGGGTGGCGCCGAGATCTACCGGCTCGC
CCTGCCCCATGCCGACCGGCTGCACCTCACCGAGGTCGATGCGGCGCCGGAGGGCGACGTGCATTTCCCGCCCTTCGACC
GCACCGCCTACCGGGAGACGCTGCGCGAGGCGCATGGACCCGGCGAGCGCGACGAATTCGCCTTCCAATTCGTCGATCTG
GAGCGGTTGGAAGGTCGTTGA

Protein sequence :
MGQPRVSLIAAVARNGVIGRDNDLVWRISSDLKRFKALTMGKPILMGRKTWDSIGRPLPGRRSLVLTRDRALTLSDVTIV
HDWDEALAAAGGDELMVVGGAEIYRLALPHADRLHLTEVDAAPEGDVHFPPFDRTAYRETLREAHGPGERDEFAFQFVDL
ERLEGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 3e-24 45
dfrA1 ADZ05803.1 trimethoprim-insensitive dihydrofolate reductase Not tested AbaR3 Protein 2e-15 42
unnamed AEL12695.1 DfrA5 Not tested AbaR21 Protein 2e-15 42
dfrA5 AFG30110.1 dihydrofolate reductase Not tested PAGI-2 Protein 7e-14 41
dfrA5 AET25387.1 dihydrofolate reductase Not tested PAGI-2(C) Protein 7e-14 41