Gene Information

Name : hom (CLH_0975)
Accession : YP_001920370.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Unknown
Product : homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 1017826 - 1019127 bp
Length : 1302 bp
Strand : +
Note : catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine

DNA sequence :
ATGAAAAAAGTTAGAATAGCACTACTAGGATTGGGGAATGTTGGTCGTGGTGTTTGTATGATTTTAAATTCTAATAAAGA
AGAAATAATGAAACGTTCAGGTTATGAAGTTGAAATTGCTAAAATCCTTGTAAGAGATGTAAGTAAAGCAAGAGGCGTTG
AAGTTTCAGAAGAACTAATAACTACAGATTTTGATGAAATATTAAATGATGATTCTATAAAAATAGTTCTTGAAATTATG
GGAGGCATAGATCCGGCTAAAGAATATATGATAAAGTGCATGAATGCAGGAAAACATATTGTAACAGCAAATAAGATGCT
GATTGCAACACATGGAGATGAACTCTTTGAAAATGCTGATAGTAATGGAGTTATGTTTAAATATGAGGCGAGTGTGGCAG
GAGGAATTCCAATAATAAACGGTATAGATGAAAGTTTGACTGCAAATAAAATAAAAGAATTATATGGAATTATAAATGGT
ACTACAAATTATATTTTAACTAAAATGGAATGTGATGGATTTGGGTTTGATGAAGCTTTAAAAGAAGCACAGGAAAAAGG
TTATGCAGAAGCAGATCCTACATCTGATATAGATGGTTATGATGCTCAATACAAATTAGCAATACTTTCATCATTAGCAT
TTGGAACAAAAGTTGATGTAGATAATGTTTATCGAGAAGGAATAACTAACATAAAGCCTATAGATATGGAATATGCAAAA
GAATTTAAAATGGTTATTAAATTACTTGCAATTGTAAAAGAAGTGAATGGAAAACTTGAATTAAGAGTTCATCCAACTAT
GATACCTAAAAAACATCCACTAGCTAATGTGTACGACTCATTTAATGCTGTGTTTGTAAAAGGAAATGCAGTTGGTGATT
TAATGTTTTATGGTAGAGGAGCAGGAGATTTGCCAACAGGTAGTGCTGTGGTTAGTGATGTTATTTCTATATTGAGAAGT
AATGTTGATTTAGAAAACTATAATTCAGTAGTGAAAAATAATTTATGGGATAGAGAAATATCAGATATTAAAGATGTTGA
AAGTAAATTTTATATTAGAGCAACTGTCTTAGATGAATCAGGAGTCTTAGGAGAAATAACTGCTATTTTAGGAAAACATA
ATGTTAGTTTAAGATCAGTTATTCAAAAAGGTGAAGAAAACGGAAAAGGTCAAGTAACAATAGTTTTAGTTACACATAAA
ACAACTCAAGCTCAAATATATAGTTCTTGCAATGAAATATCTAATTTAAGTTCTGTAAATAAAATAGATAATATAATAAG
AATAGAGGATTTTAAAGAGTAG

Protein sequence :
MKKVRIALLGLGNVGRGVCMILNSNKEEIMKRSGYEVEIAKILVRDVSKARGVEVSEELITTDFDEILNDDSIKIVLEIM
GGIDPAKEYMIKCMNAGKHIVTANKMLIATHGDELFENADSNGVMFKYEASVAGGIPIINGIDESLTANKIKELYGIING
TTNYILTKMECDGFGFDEALKEAQEKGYAEADPTSDIDGYDAQYKLAILSSLAFGTKVDVDNVYREGITNIKPIDMEYAK
EFKMVIKLLAIVKEVNGKLELRVHPTMIPKKHPLANVYDSFNAVFVKGNAVGDLMFYGRGAGDLPTGSAVVSDVISILRS
NVDLENYNSVVKNNLWDREISDIKDVESKFYIRATVLDESGVLGEITAILGKHNVSLRSVIQKGEENGKGQVTIVLVTHK
TTQAQIYSSCNEISNLSSVNKIDNIIRIEDFKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 4e-69 42
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 4e-69 42