Gene Information

Name : kdpA (CLH_0915)
Accession : YP_001920310.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Unknown
Product : potassium-transporting ATPase subunit A
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2060
EC number : 3.6.3.12
Position : 946860 - 948599 bp
Length : 1740 bp
Strand : +
Note : catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

DNA sequence :
ATGATGAATTTAGTATTACAATATGGATTGTATATTTTGATATTAGTAGTATTGGCAATTCCTTTAGGGAATTATATAGG
TAAGATTATGAATGGAGAAAAAGTGTTTTTATCTAAGATATTAACACCGTGTGAAAATTTTATTTATAAAATGCTTCATA
TTGATAAAGATGAAGATATGAGTTGGAAGAAGTATTCTTTTTCTGTTTTAGCATTTTCAATTATAAGTTTAATAGTATTA
TTTTTAATACACATTTTCCAAGGCTTTTTGCCATTAAATCCAGAAAAAGTTTCAGGTACAAGCTGGGATCTTGCATTTAA
TAATGCGGTAAGTTTTGTTACTAATACTAATTGGCAAGGTTATTCAGGTGAAAGTTCATTGAGCTATTTCACACAAATGA
TGGGACTGACTGTACAAAATTTTGTTTCGGCAGCAGTTGGTATTTCAGTATTATTCGCACTAATTAGAGGATTTATTAGA
GTTAAGCAAAAAGGAATAGGAAACTTTTGGATGGATATTACTAGAACTGTACTTTATATCTTGATTCCTCTTTCAATAGT
AGTATCTTTAGCATTAGTTTCTCAAGGTGTTGTACAAAATTTCAAACAATATGAAACAGTTTCTTTATTAGAGCCTATTA
CACTTGAAGATGGAACCGTAGTAACTGAAGAAGTTGTTCCGTTAGGACCAGCAGCAAGTCAAATAGCAATAAAGCAACTT
GGTACAAATGGCGGAGGATTTATGGGTACTAATTCAGCACACCCAATTGAAAATCCAACCGTATTATCTAATTTATTTGA
AATGATTTCGTTACTATTAATCCCAGTAGCCTTATGTTTTACTTTTGGGAGAAATATAAAAGATAGAAGACAAGGAATAG
CTATATTTATAGCAATGGGTATAATGCTAGTTGTAGCAATGGGAATTATTGGAGTAAATGAGCAAATGGGTACACCACAA
ATGGCGTTAAATGGTCAGGTTGACTTATCAACAATTAATCAAGCTGGTGGAAATATGGAAGGAAAAGAAGCTAGATTTGG
TATTGCCACTTCTTCAACATGGGCAACATTTACTACTGCAGCATCTAATGGATCAGTAAATTCAATGCATGATAGTTATA
CTCCAATTGGTGGAATGATTCCTATGCTACTTATGCAACTTGGAGAAGTTGTATTTGGAGGTGTTGGATGTGGGCTTTAT
GGGATGATAGGTTTTGCAATACTTGCAGTATTTATGGCAGGACTTATGGTAGGAAGAACACCAGAATATTTAGGTAAAAA
AATAGAACCTTTTGAAATGAAAATGGCAGTTTTAGTTTGTTTAGCAACACCAATAGCTATTTTAATTGGTAGTGGTATTG
CAAGTATATTACCTGAGACTGTTAACAGTTTGAATAATTCAGGGGCGCATGGATTTTCAGAAGTATTATATGCTTACACT
TCAGCAGGGGGTAATAATGGTTCAGCATTTGCTGGTTTTGCAGCGAATACACCATTTATAAATATAAGTATTGGGTTAAG
TATGCTATTTGCACGTTTTGTTCCTATGATGGGTACTTTGGCTATAGCAGGAAGCATGGTTAAAAAGAAAAAAGTTGCAG
AAAGTGTTGGTACATTACCTACACATAATGCTATGTTTATAGGACTTTTAATTTTTGTTGTATTGCTTATTGGTGCATTA
AGTTTCTTTCCAGCATTGGCACTTGGACCAATTGCTGAATTCTTTCAAATGTTAGGTTGA

Protein sequence :
MMNLVLQYGLYILILVVLAIPLGNYIGKIMNGEKVFLSKILTPCENFIYKMLHIDKDEDMSWKKYSFSVLAFSIISLIVL
FLIHIFQGFLPLNPEKVSGTSWDLAFNNAVSFVTNTNWQGYSGESSLSYFTQMMGLTVQNFVSAAVGISVLFALIRGFIR
VKQKGIGNFWMDITRTVLYILIPLSIVVSLALVSQGVVQNFKQYETVSLLEPITLEDGTVVTEEVVPLGPAASQIAIKQL
GTNGGGFMGTNSAHPIENPTVLSNLFEMISLLLIPVALCFTFGRNIKDRRQGIAIFIAMGIMLVVAMGIIGVNEQMGTPQ
MALNGQVDLSTINQAGGNMEGKEARFGIATSSTWATFTTAASNGSVNSMHDSYTPIGGMIPMLLMQLGEVVFGGVGCGLY
GMIGFAILAVFMAGLMVGRTPEYLGKKIEPFEMKMAVLVCLATPIAILIGSGIASILPETVNSLNNSGAHGFSEVLYAYT
SAGGNNGSAFAGFAANTPFINISIGLSMLFARFVPMMGTLAIAGSMVKKKKVAESVGTLPTHNAMFIGLLIFVVLLIGAL
SFFPALALGPIAEFFQMLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0087 AAM75290.1 EF0087 Not tested Not named Protein 2e-93 51
kdpA NP_814333.1 potassium-transporting ATPase subunit A Not tested Not named Protein 2e-93 51
unnamed BAB43902.1 potassium-transporting ATPase(A chain) Not tested Type-II SCCmec Protein 1e-59 41
SAR0070 YP_039538.1 potassium-transporting ATPase subunit A Not tested Type-II SCCmec Protein 2e-59 41
truncated-kdpA NP_370596.1 potassium-transporting ATPase subunit A Not tested Type-II SCCmec Protein 2e-59 41
kdpA NP_373308.2 potassium-transporting ATPase subunit A Not tested Type-II SCCmec Protein 2e-59 41
kdpA YP_190030.1 potassium-transporting ATPase subunit A Not tested Type-II SCCmec Protein 2e-59 41
kdpA YP_251948.1 potassium-transporting ATPase subunit A Not tested SCCmec Protein 1e-60 41