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Name : secA (CLH_0512) Accession : YP_001919913.1 Strain : Clostridium botulinum Alaska E43 Genome accession: NC_010723 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 509202 - 511712 bp Length : 2511 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGGATTATTAAGTGCCGTATTTGGAACATATAGTGAAAGAGAAGTAAAGAGAATTAGACCTATTGTCAGCAAAATAAA TGAATTAGACGAAGTCATGCAAAAACTTTCAGATGATGAATTAAAGGCAAAGACTGTAGAGTTTAAAGAAAGACTTAATA ATGGTGAAACTGTAGATGATATTTTACCAGAAGCATTTGCCGTAGTTAGAGAAGCGTCTAAAAGAGTGTTAAATATGAAG CATTATGATGAACAACTTATTGGTGGAGTTGTTTTACATCAAGGTAGAATAGCTGAAATGAAAACTGGAGAAGGTAAAAC ATTAGTTGCAACTTTACCAGCATATTTAAACGGATTAACAGGCAAAGGTGTTCATATAATAACAGTTAATGATTATCTTG CAAAAAGAGATGCTGAACAAATGGGAGAATTATATGGCTTTTTAGGATTGACAACGGGTGTTATTGTTCATGAGTTAACT AATGAGCAAAGAAGAGAAGCATATAACTCAGATATAACTTATGGAACAAATAATGAATTTGGTTTTGATTATTTAAGAGA TAACATGGTTATATATAAGGAAGAAAGAGTTCAAAGAAAACTGAACTTTACTATAGTAGATGAAGTTGACTCAATATTAA TTGATGAAGCTAGAACTCCACTTATAATTTCTGGTCAAGGAGAAAAGTCTACAGAATTTTACAAAGTAGCAGATTATTTT GTTAAAACATTAGTAAAAGAAAAAGATTATACAATAGATGAAAAAGCTAATGCAGTAATGCTAACTGATGAAGGTTTCCA TAAAGCAGAACAAACTTTTAAAGTAGAAAATTATGCAGATGCTGAAAATGTAGAATTACAACATTATGTTACTCAAGCAT TAAAAGCTAACTATGCAATGAGAAGAGATAAAGATTACATGGTTAAAGATGGAGAAGTAATAATTGTTGATGAATTTACA GGAAGACTTATGGAAGGAAGACGATATTCAGATGGTCTTCATCAAGCAATAGAAGCTAAGGAAAATGTTAAAATTGCAAG AGAATCTAAGACATTAGCAACTATTACGTTCCAAAATTACTTCAGAATGTATGAAAAATTATCAGGAATGACAGGTACAG CTTTAACAGAAGAAAATGAATTTAGAGAAATTTATGGATTAGACGTTATTGTTGTTCCAACTCATAAACCAGTTGTTAGA ATAGATAATCCTGATTTAGTATTTAAGAGTGAAAAAGGAAAGATCATGGCTGTTGTAGATGAGATAGCAAAAGCACATGA AGTAGGGCAACCAGTATTAGTTGGTACTGTAAGTATTGAAAAATCAGAATTGATTTCAAGTATGCTTAAGAAAAAGGGAG TCCCACATCAAGTTTTAAATGCAAAATTCCATGAACAAGAAGCAGAAATAATAACACATGCTGGTGAAAAAGGTATGGTT ACTATAGCCACTAATATGGCTGGTAGAGGTACTGATATTAAGCTTGGTGAAGGTGTTCTTGAAATTGGTGGACTTAAGAT AATAGGTACTGAAAGACATGAATCAAGAAGAATAGATAACCAATTAAGAGGACGTTCTGGTAGACAAGGAGATAGTGGAG AATCAACATTCTTTATTTCATTAGAAGATGATTTAATGAGAATTTTTGGATCAGAAAAGATTCAAGGTGTTGTTGAAAAA CTTGGTCTTGAAGAAGATGAAGCAATTGAAAGTAAACTTGTTTCTAAATCTATAGAAAATGCTCAAAAGAAGGTTGAAGG TAATAACTTTGATATAAGAAAAACATTATTAGGATATGATGATGTTATGAATAAACAAAGAGAGGTTATTTACAAGCAAA GATCAGAAGTTCTTGAAGGTGAAGATGTAAAAGAAGAAATATTACATATGCTAAGAGATGTAATATCAGATGCAGTTAAT ACTCATATTAAAGAAGATGCTGAAGATTATAGAGAAAGCTTTTTATATTTAATATCTTATTTAAATGACATATGTATACC AACAAATGAGGTTAATTTACCTGCTCTTGCAGATATGTCAAAAGAAGAGATTGTAGATCATTTATATGATGTAGCAGTTA AAAGTTATGAAAATAAAGAAGCTGAATTTACACCTGAAAGATTAAGAGAAATAGAAAGAGTTGTTCTTTTAAGATCTGTT GATACAAAGTGGATGGATCATATTAATAATATGGATAACTTAAAACAAGGTATTGGACTTAGAGCATTCAAACAAGTAGA TCCTGTTCAAGCTTATCAAATGGAAGGTAGCGCTATGTTTGAAGAAATGATAGATTCTATTAAGAATGAAACTGTAAAGA TGTTATTCCATGTTAAAGTGGAAAGAGCACCTGAAAGAGTTAGAGTTGCGCAAGAAACAAATGCAGTACATGGAGATAAG CCATCAGCTCCAGTAGGTCCAGTTAGAAATCTTAATAAATTTGGAAGAAATGACGTATGTCCATGCGGAAGTGGAAAGAA GTTTAAAAATTGTTGTGGTAGAGAAGCTTAA Protein sequence : MGLLSAVFGTYSEREVKRIRPIVSKINELDEVMQKLSDDELKAKTVEFKERLNNGETVDDILPEAFAVVREASKRVLNMK HYDEQLIGGVVLHQGRIAEMKTGEGKTLVATLPAYLNGLTGKGVHIITVNDYLAKRDAEQMGELYGFLGLTTGVIVHELT NEQRREAYNSDITYGTNNEFGFDYLRDNMVIYKEERVQRKLNFTIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF VKTLVKEKDYTIDEKANAVMLTDEGFHKAEQTFKVENYADAENVELQHYVTQALKANYAMRRDKDYMVKDGEVIIVDEFT GRLMEGRRYSDGLHQAIEAKENVKIARESKTLATITFQNYFRMYEKLSGMTGTALTEENEFREIYGLDVIVVPTHKPVVR IDNPDLVFKSEKGKIMAVVDEIAKAHEVGQPVLVGTVSIEKSELISSMLKKKGVPHQVLNAKFHEQEAEIITHAGEKGMV TIATNMAGRGTDIKLGEGVLEIGGLKIIGTERHESRRIDNQLRGRSGRQGDSGESTFFISLEDDLMRIFGSEKIQGVVEK LGLEEDEAIESKLVSKSIENAQKKVEGNNFDIRKTLLGYDDVMNKQREVIYKQRSEVLEGEDVKEEILHMLRDVISDAVN THIKEDAEDYRESFLYLISYLNDICIPTNEVNLPALADMSKEEIVDHLYDVAVKSYENKEAEFTPERLREIERVVLLRSV DTKWMDHINNMDNLKQGIGLRAFKQVDPVQAYQMEGSAMFEEMIDSIKNETVKMLFHVKVERAPERVRVAQETNAVHGDK PSAPVGPVRNLNKFGRNDVCPCGSGKKFKNCCGREA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 6e-132 | 41 |
