Gene Information

Name : rph (CLH_0403)
Accession : YP_001919836.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 423461 - 424210 bp
Length : 750 bp
Strand : +
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
TTGAGAATTGATGGAAGAAAAAATGAGCAAATAAGACATGTTAAAGTGACAAGACATTATACAAAGTATGCAGAAGGTTC
AGTATATATAGAAGTGGGAGACACAAAAGTTTTATGTAATGTTTCTATTGAAGATAAAGTTCCACCATTTATGAAAGGAA
CAGGATCAGGATGGATTACAGCAGAATATAATATGCTTCCAAGATCAACAGAAACAAGAAAGATAAGAGATATTGCAAGA
TTAAAAATAGATGGCAGAACAATGGAGATACAAAGACTTATAGGAAGAGCTTTGAGATCTGTTGTAGATTTAAAGGCTTT
AGGTGAAAAGACATTATGGATTGATTGTGATGTTATTCAAGCTGATGGTGGCACAAGAACTACAGCTATTTCAGGAGCAT
TTATAGCATTAGTTGACGCTGTTAATAAATTGCACAAAATAAAGCCTTTTAAAATATATCCTATCAGAAGTTTTGTTGCA
GCAGTGAGTGTTGGTATAGTTAATGAAGAAAAAATATTAGATTTGTGTTATCAAGAAGATTCAAAAGCAAAAGTAGATAT
GAATATAATTATGACTGATGAAGGTAGTTTTGTTGAAGTTCAAGGTACTGGAGAAGAGAGTCCATATACTAGAACTGAGT
TAAATGAATTATTAGATTTAGGAGAAAAGGGAATAAAACAAATGATTAATGTTCAAAAAGAATCATTAAAAATGGATTCT
CTTTGGATTGGTACAGGAGGTAATAATTAG

Protein sequence :
MRIDGRKNEQIRHVKVTRHYTKYAEGSVYIEVGDTKVLCNVSIEDKVPPFMKGTGSGWITAEYNMLPRSTETRKIRDIAR
LKIDGRTMEIQRLIGRALRSVVDLKALGEKTLWIDCDVIQADGGTRTTAISGAFIALVDAVNKLHKIKPFKIYPIRSFVA
AVSVGIVNEEKILDLCYQEDSKAKVDMNIIMTDEGSFVEVQGTGEESPYTRTELNELLDLGEKGIKQMINVQKESLKMDS
LWIGTGGNN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 7e-61 53