Gene Information

Name : dnaB (CLH_3374)
Accession : YP_001922697.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 3637108 - 3638448 bp
Length : 1341 bp
Strand : -
Note : unwinds double stranded DNA

DNA sequence :
TTGGAATCACAAGTTATGAGAACTTTACCTCAGAGCATAGAAGCTGAACAATCAGTAATAGGTTCTATGATCATAGATAA
ATCTGCTATTGCTAAAGTTTTAGAAAGTTTAGAAGAAGAAGATTTTTATAGAGATGGTCATAAAGTAATATTTAGAGCTA
TATTAGATATGTTTAGAAAAGATATGGCTGTAGATTTAGTTACTCTGTTAGAAAGTTTAAAAAGTACTGAGATGCTTGAA
AGAGCAGGTGGAGTAACTTATATAACAGAAATAAGTGCATCAGTTCCTACTACAGCAAATTTATCTTCTTATATAAAAAT
AGTAGAAGAAAAATCAGTTTTAAGAAAACTTATAAAGGCTTCAACATCTATAATAGAATCTAGCTATAATAATCAAGGTG
AGGTTGAGAATGTATTAGATGGAGCTGAAAAAAGAATATTTGATATAGCCGAAAAGAAAACTTCAAAGGATTTTGAACCT
TTAAGTGATGTTTTAGAAAGAGGTTTTCTTGAAATAGAGAGACTTTTTAATAATAGAGGTGAGATTACAGGGGTAGGGTC
TGGATTTTCAGATTTAGATTCTAAAACATCAGGATTTCAAAAGGGTGATATGATTCTGATTGCCGCTAGACCATCTATGG
GAAAGACTACTTTTGCATTAAATATAGCTGAACATGCAGCATTAAGAGAAGGTAAAAGTGTAGTTATATTCTCACTAGAA
ATGTCAAAGGAGCAATTAGCATATAAATTGCTTTGCTCTGAAGCAAATGTTGATATGCTAAGACTTAGAACAGGTGAATT
AGATGATAAAGACTGGGAAAACATTGCAAAAGCTACAGGGCCTTTAGCTAAAGCAAAGGTTTATATAGATGATACGGCTG
GAGTATCTGTTATGGAAATGAGATCTAAATGTAGAAGATTGAAAATGGAATATGGAATAGATTTAATAGTTATAGATTAT
TTACAGCTTATGTCTGGAAGCACAGGAAGTAGTGATAATAGACAACAAGAAGTATCAGAAATATCAAGATCTATAAAAGC
ATTAGCTAAGGAAATGGAATGTCCTGTTATAGCACTATCTCAATTATCTCGTGCACCTGAACAAAGAGCTGATCACAGAC
CTATGTTATCAGATTTAAGAGAATCAGGCTCTATAGAACAGGATGCCGATCTTGTTATGTTCTTATATAGAGATGAGTAC
TATAACAAGGAAACTGAAGATAAAAATATTGGTGAATGTATAATAGCAAAACAAAGAAATGGTCCAGTAGGAACAGCTAA
ACTTGCTTGGCTTGGTCAATACAGTAAATTTGGAAATTTAGATGTTATTCATAAAGAATAA

Protein sequence :
MESQVMRTLPQSIEAEQSVIGSMIIDKSAIAKVLESLEEEDFYRDGHKVIFRAILDMFRKDMAVDLVTLLESLKSTEMLE
RAGGVTYITEISASVPTTANLSSYIKIVEEKSVLRKLIKASTSIIESSYNNQGEVENVLDGAEKRIFDIAEKKTSKDFEP
LSDVLERGFLEIERLFNNRGEITGVGSGFSDLDSKTSGFQKGDMILIAARPSMGKTTFALNIAEHAALREGKSVVIFSLE
MSKEQLAYKLLCSEANVDMLRLRTGELDDKDWENIAKATGPLAKAKVYIDDTAGVSVMEMRSKCRRLKMEYGIDLIVIDY
LQLMSGSTGSSDNRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADLVMFLYRDEY
YNKETEDKNIGECIIAKQRNGPVGTAKLAWLGQYSKFGNLDVIHKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 5e-78 42
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 2e-78 42
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 1e-75 42
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 6e-81 42
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 1e-73 42
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 1e-73 42