Gene Information

Name : purA (CLH_3370)
Accession : YP_001922693.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 3632335 - 3633621 bp
Length : 1287 bp
Strand : -
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGTCAGCATTTATTGTTTTAGGAGCCCAATGGGGAGATGAAGGAAAAGGAAAGATGACAGATTATTTAGCGGAAGAAGC
TGAAGTTGTTGTTAGATTTCAAGGAGGTAATAATGCTGGTCATACTGTAGAAGTTGGAGATAAGCAATATAAATTGCACT
TAATTCCATCAGGAATACTATATGATGATAAATTAAATGTTATTGGAAATGGAGTAGTAGTAGATCCTAAAGCTCTATTT
GAAGAAATAAATTATTTAGAAGGTGTAGGAGTTAAAGTTACACCAGAAAAATTAATCATAAGTGATAGAGCACAACTTAT
AATGCCATATCATAAGACACTAGATGTTTTAAAAGAAAAAGCAAGAGGTAAAAATGATATAGGAACTACAGGAAAGGGCA
TAGGTCCATGTTACACAGACAAATTTGAAAGATGTGGAATTAGAGTTTGTGACCTTATGCATGAAGATGTTTTTAAAGAA
AAATTAGAAGAAAATATAAGAATGAAAAATGAGTATATTACTAAGGTATTAGGTGGAGAACCTTTAAGTTTTAGTGAAAT
ATTAAATGAATATTTAGAATTTGCAAAGAAATTAAGACCTTTTGTTCAAGATACTTCAGTTAAGGTTTATGACAATATTA
AAGAAAATAAAACTGTACTATTTGAAGGTGCACAAGGTATGCTACTAGATATAGATTACGGAACATATCCTTATGTTACA
TCATCTAACACAACAGCTGGTGGTGTATGTAGTGGTATAGGTGTTGGACCTAACATGGTAACTAATGCAGTAGGTATAAC
AAAAGCTTATACTACAAGAGTTGGTAAAGGACCATTCCCAACAGAATTAATTGATGAAACTGGAGACTGGATAAGAGAAA
AAGGTCATGAATATGGAGTAACAACAGGAAGATCAAGAAGATGTGGTTGGTTAGACTTAGTTATAGTTAAAACTGCTGCA
AGAGTAAGTGGATTGACTTCATTAGCTGTTACTAAGATAGATACATTAGCAGGATTAGAAAAATTAAAAGTATGTGTAGG
ATATAAATTTGATGGTAAAGTTATAGATTACTTCCCAGCAAGCTTAGAAGATTTAGCTAAATGTGAACCAGTATATGAAG
ATTTTGATGGTTGGGATGATAGCGTAGCAGAAGCTAGAACATATGAAGAACTACCTGAAAATGCTAAGAAATACTTAAAT
AGAATAGCTGAATTTACAGATACTAAGATTTCTATAATAGGTGTTGGACCAAAGAGAGAACAAACTATAAGAATAGATAG
TATATAA

Protein sequence :
MSAFIVLGAQWGDEGKGKMTDYLAEEAEVVVRFQGGNNAGHTVEVGDKQYKLHLIPSGILYDDKLNVIGNGVVVDPKALF
EEINYLEGVGVKVTPEKLIISDRAQLIMPYHKTLDVLKEKARGKNDIGTTGKGIGPCYTDKFERCGIRVCDLMHEDVFKE
KLEENIRMKNEYITKVLGGEPLSFSEILNEYLEFAKKLRPFVQDTSVKVYDNIKENKTVLFEGAQGMLLDIDYGTYPYVT
SSNTTAGGVCSGIGVGPNMVTNAVGITKAYTTRVGKGPFPTELIDETGDWIREKGHEYGVTTGRSRRCGWLDLVIVKTAA
RVSGLTSLAVTKIDTLAGLEKLKVCVGYKFDGKVIDYFPASLEDLAKCEPVYEDFDGWDDSVAEARTYEELPENAKKYLN
RIAEFTDTKISIIGVGPKREQTIRIDSI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 2e-121 54