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Name : pyk (CLH_3086) Accession : YP_001922463.1 Strain : Clostridium botulinum Alaska E43 Genome accession: NC_010723 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 3326418 - 3327833 bp Length : 1416 bp Strand : - Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064 DNA sequence : ATGAGAAAGACTAAAATGATTTGTACTATTGGACCAGCAAGTGAAGACAGAGAAATATTAGAACAAGTAATGTTAGCAGG AATGAATGCTTCAAGACATAACTTTTCACACGGTGATCACGAAGAACATAGAGGAAGAATAGAAAAAGTTAAAGAATTAT CAAAGAAACTTGATAAAGAAATAGCTATCATCCTTGATACAAAAGGACCAGAAATAAGAACTGGAAAATTCGAACCAAAC AAAGTTGAATTAGTTAAAGGTACAGAATTTACAGTATATGCAGGAGATATGTCAGTAGTTGGAGACACTACAAAGTGTGC AGTTACTTACGAAGGATTAGCTAATGATGTTAAACCAGGAAACACTATCTTAATAGATGATGGTTTAGTAGGATTAACAG TTAAATCAGTAGAAGGAAACGCAGTTATCTGTGAAGTTCAAAATACTGGATTAGTTGGAACTCACAAAGGTGTTAATGTA CCAGGAGTTTCAATCCAATTACCAGCTCTTACTGAAAAAGATAAATCAGATTTAATATTTGGTTGTGAAATGGGAGTTAC TATGATTGCAGCTTCATTCGTAAGAAAAGCAGCTGACGTAGTAGCAATAAGAAAAGTTCTTGATGAAAATGGTGGAAAGA ACATATTAATATGCCCTAAAATCGAAAACCAAGAAGGTGTTGATAACATCGATTCAATCTTAGAAATCTCAGATGCTGTA ATGGTAGCTAGAGGAGATCTAGGTGTTGAAATTCCAATAGAACAAGTACCAGCAGTTCAAAAAATGATCATTCAAAAATG TAATGCAGCTGGAAAGCCAGTTGTTACTGCAACTCAAATGTTAGATTCTATGATCAGAAACCCAAGACCAACAAGAGCTG AAGTTTCAGATGTAGCTAACGCTATATTAGATGGTACTGATGCAATAATGTTATCAGGAGAAAGTGCTAACGGAACTTAC CCAGTAGAAGCTGTTAGAACTATGGCTAAAATTGCTGCAGAAACTGAAAAGCAATTAGCTCATAAAGTTGCTTACTCAAA TGATAAATCATCAATGTCAGAAGTAATTTCAAGAGCAGCATGTAATGCAGCTAATGAATTAGAAGCAACTGCTATAATTT CTTCAACTCAAACAGGAGCTACTGCTAAGAGAATATCTAAGTCTAGACCAGACTGTACAATCATAGCTGTTACTCCAGAT GAAGTAGTAGCAAAACAATTAGCATTCTCATGGGGAGTTTACCCAATAGTTGCTGATAAAATGTCTTCAACTGACGAAAT GATGACAAAATCAGTTGAAATAGCAAAAGAACATAACTATGTTAAAAATGGTGATACAGTAGTTTTAGCTGCTGGAGTTC CAGTTGATAAGACAGGAACAACTAACCTATTAAAAGTTAGCGTAGTAGGCGAATAA Protein sequence : MRKTKMICTIGPASEDREILEQVMLAGMNASRHNFSHGDHEEHRGRIEKVKELSKKLDKEIAIILDTKGPEIRTGKFEPN KVELVKGTEFTVYAGDMSVVGDTTKCAVTYEGLANDVKPGNTILIDDGLVGLTVKSVEGNAVICEVQNTGLVGTHKGVNV PGVSIQLPALTEKDKSDLIFGCEMGVTMIAASFVRKAADVVAIRKVLDENGGKNILICPKIENQEGVDNIDSILEISDAV MVARGDLGVEIPIEQVPAVQKMIIQKCNAAGKPVVTATQMLDSMIRNPRPTRAEVSDVANAILDGTDAIMLSGESANGTY PVEAVRTMAKIAAETEKQLAHKVAYSNDKSSMSEVISRAACNAANELEATAIISSTQTGATAKRISKSRPDCTIIAVTPD EVVAKQLAFSWGVYPIVADKMSSTDEMMTKSVEIAKEHNYVKNGDTVVLAAGVPVDKTGTTNLLKVSVVGE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-110 | 54 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-110 | 54 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-110 | 54 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 1e-109 | 54 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pyk | YP_001922463.1 | pyruvate kinase | VFG0479 | Protein | 4e-111 | 54 |
