Gene Information

Name : hemC (CLH_2649)
Accession : YP_001922029.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2804062 - 2804934 bp
Length : 873 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAATGAATTAATAATAGCAACTAGAAAAAGTAAGTTGGCTCAAGTTCAAACTGAAATAATTATGAGTGAATTGAAATC
AAAATTTAATATAGATAGTAAAAAATTACTTATAGTAACTGAGGGAGATAGAAAATTAGATGTTTCATTAAATAAAATAG
GGGGTAAAGGACTTTTTGTTAAGGATATAGAACTTGCTCTTTTAAATAAGGAAGCTCACGCTGCAGTTCATAGTATGAAA
GATGTTCCTTTTGAAGTTAGTAGTGAATTTGAAATTACAGCTATAACAGGAAGAGAAGATATAAGGGATGTATTTATTTC
AAATGGAGATATCTCATTTAAAGATATTAAAAAAGGCGCTAAAGTAGGAACAAGTAGTATAAGAAGAGCAGCACAGCTGA
AACTTCTAAGAAGTGATTTAGAGATAGTACCTATAAGAGGTAATGTTCAAACTAGATTAAAGAAAATGGAAGAGCAAAAT
TTAGATGGAATAGTTTTAGCAGCAGCAGGCCTTAAAAGACTTGGTGATGAAAATTTAATAACAGATTATTTTGATCCAAA
AGAATTTTTACCAGCGGTTTCTCAAGGGGCACTTGGAATTGAGTGCTTAAAAGATGGCGATGCTAATAAATATTTTGAAG
CTTTAATAGATGCAGAAGCGACTTTGACTGTGGAAGCTGAAAGAAGTTTTATGAAAGAATTACAAGGAGATTGTCATAGC
CTTATTGGAGCTTATTCTGAAATTCAAGGTGATGATTTATATATGATTGGAATATATGATATAGGTGGAAAAATAGTTAA
AAAAGATATTTTAGGATGTAAAACTAATAATATTGAATTAGGAAAAAAATTAGCACAAAAAATATTAGGATAA

Protein sequence :
MNELIIATRKSKLAQVQTEIIMSELKSKFNIDSKKLLIVTEGDRKLDVSLNKIGGKGLFVKDIELALLNKEAHAAVHSMK
DVPFEVSSEFEITAITGREDIRDVFISNGDISFKDIKKGAKVGTSSIRRAAQLKLLRSDLEIVPIRGNVQTRLKKMEEQN
LDGIVLAAAGLKRLGDENLITDYFDPKEFLPAVSQGALGIECLKDGDANKYFEALIDAEATLTVEAERSFMKELQGDCHS
LIGAYSEIQGDDLYMIGIYDIGGKIVKKDILGCKTNNIELGKKLAQKILG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-46 44
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-46 44