Gene Information

Name : CLH_2560 (CLH_2560)
Accession : YP_001921940.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease protein MacB 2
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 2708733 - 2709470 bp
Length : 738 bp
Strand : -
Note : identified by match to protein family HMM PF00005

DNA sequence : 
TTGACCAATAATATAATTGAAATGAATAATATTGTAAAGAGCTTCTATATAGGAACTGAGAATCAATTAGATATTTTAAA
AAACATTGATATAAATGTAAAAAAAGGCGAATTTATATCAATAGTAGGGGCTTCTGGATCTGGTAAAAGTACTTTAATGA
ACATTATAGGAGCTTTGGACAGACCTACATCTGGAACTTATATATTAGATAGTACTAATATAAATGATATATCAGACAAT
GGATTATCAGAAATACGTAATAAAAAAATAGGTTTTGTATTTCAAACATTTAATTTAATACCAAGAAGTAGTGCACTTAA
AAATGTTGAGTTACCAATGCTTTATGCAGGAGTAGATAAAAAAGTCAGAATAGAACGTGCTAAAAAACTTTTAGAGCTTG
TAGGAATGGAAGATAGAATTAATCATCTTCCAAATGAGCTTTCTGGTGGTCAGAAGCAAAGAGTAGCAATAGCTAGGGCT
TTAGTCAATGATCCAAGTATAATACTTGCTGATGAACCTACAGGAGCATTAGATTCAGAAACTGGAAGATTAGTTATGGA
TTTATTTCATAAAGTACATGAAACAGAAGGAAAGACTATTGTATTTATAACTCATAATTATGAATTGGCATTAGAAACTG
AAAGAATTATAACGTTGAAGGATGGAAAGATAATATCTGATGACTATAATAAGAATTATTCTAAGAAATTTCCAGATGGT
GAAAAGTTATGTTTATAA

Protein sequence : 
MTNNIIEMNNIVKSFYIGTENQLDILKNIDINVKKGEFISIVGASGSGKSTLMNIIGALDRPTSGTYILDSTNINDISDN
GLSEIRNKKIGFVFQTFNLIPRSSALKNVELPMLYAGVDKKVRIERAKKLLELVGMEDRINHLPNELSGGQKQRVAIARA
LVNDPSIILADEPTGALDSETGRLVMDLFHKVHETEGKTIVFITHNYELALETERIITLKDGKIISDDYNKNYSKKFPDG
EKLCL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 1e-32 43
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 9e-34 42
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 9e-34 42
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 9e-34 42
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 2e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLH_2560 YP_001921940.1 macrolide export ATP-binding/permease protein MacB 2 NC_012469.1.7686878. Protein 3e-52 53
CLH_2560 YP_001921940.1 macrolide export ATP-binding/permease protein MacB 2 CP001581.1.gene798.p Protein 1e-39 47
CLH_2560 YP_001921940.1 macrolide export ATP-binding/permease protein MacB 2 CP001581.1.gene598.p Protein 4e-39 43
CLH_2560 YP_001921940.1 macrolide export ATP-binding/permease protein MacB 2 NC_008702.1.4606598. Protein 3e-41 41