Gene Information

Name : CLH_2461 (CLH_2461)
Accession : YP_001921842.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Resistance
Product : regulatory protein VanR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2631884 - 2632570 bp
Length : 687 bp
Strand : -
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence : 
ATGAAGGGATATATTCTTATAGTTGATGATGATGAAAATATAAGAAATTTATTGAGTATCTATTTAGAAAATGAAAATTT
TAAAACTATAAAGGCAGAGAATGCTAAAGAAGCAATTAAAATCATAGATGAGAAAGAAATAGAACTAGTTCTTTTAGATA
TAATGATGCCACAAATAGATGGAATTGAGGCATGTATGAGAATAAGAAAAGATAAAAATATGCCAATAATTATGATATCT
GCAAAATCAGAAGATATGGATAAAATTCACGGATTAACAGCTGGCGCAGATGATTATATAACAAAACCATTTAATCCATT
AGAACTTATAGCTAGGGTAAAATCTCAGCTTAGAAGGTATCAAAAATATAATACAGGTTCAAATAATCAAAAAGTTATAA
TTGAAATTGGAGATTTGACTATTAATACTGATACTAGACAAATTTGGGTTGGAGAAAAAGAAGTAAGGTTAACTCCAAAG
GAATTTGATATTTTAGAATTACTAGCAAGAAATAAAGGGATTGTTTTAAGCATAAGAAAAATATATGAAGAGGTTTGGAA
AGAGGAATTTTTCAAATCAGATAATACTGTTACAGTTCATATAACGAATTTAAGAGAAAAAATTGAAGCTGATCCTAAAG
CTCCTGTATATATAAAAACAATATGGGGAGTAGGCTATAAGATATGA

Protein sequence : 
MKGYILIVDDDENIRNLLSIYLENENFKTIKAENAKEAIKIIDEKEIELVLLDIMMPQIDGIEACMRIRKDKNMPIIMIS
AKSEDMDKIHGLTAGADDYITKPFNPLELIARVKSQLRRYQKYNTGSNNQKVIIEIGDLTINTDTRQIWVGEKEVRLTPK
EFDILELLARNKGIVLSIRKIYEEVWKEEFFKSDNTVTVHITNLREKIEADPKAPVYIKTIWGVGYKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nisR2 YP_006309922.1 NisR Not tested FWisland_1 Protein 1e-24 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLH_2461 YP_001921842.1 regulatory protein VanR NC_005054.2598277.p0 Protein 1e-50 52
CLH_2461 YP_001921842.1 regulatory protein VanR NC_014475.1.orf0.gen Protein 1e-50 52
CLH_2461 YP_001921842.1 regulatory protein VanR AM180355.1.gene1830. Protein 1e-46 50
CLH_2461 YP_001921842.1 regulatory protein VanR AF155139.2.orf0.gene Protein 6e-46 49
CLH_2461 YP_001921842.1 regulatory protein VanR DQ212986.1.gene4.p01 Protein 6e-43 48
CLH_2461 YP_001921842.1 regulatory protein VanR FJ349556.1.orf0.gene Protein 5e-46 48
CLH_2461 YP_001921842.1 regulatory protein VanR AF130997.1.orf0.gene Protein 5e-42 47
CLH_2461 YP_001921842.1 regulatory protein VanR EU250284.1.orf4.gene Protein 3e-46 47
CLH_2461 YP_001921842.1 regulatory protein VanR AF162694.1.orf4.gene Protein 3e-44 47
CLH_2461 YP_001921842.1 regulatory protein VanR AF253562.2.orf0.gene Protein 2e-31 43
CLH_2461 YP_001921842.1 regulatory protein VanR NC_012469.1.7686381. Protein 3e-39 42
CLH_2461 YP_001921842.1 regulatory protein VanR HE999704.1.gene2815. Protein 2e-37 42
CLH_2461 YP_001921842.1 regulatory protein VanR CP001581.1.gene280.p Protein 4e-38 41
CLH_2461 YP_001921842.1 regulatory protein VanR NC_012469.1.7685629. Protein 2e-31 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLH_2461 YP_001921842.1 regulatory protein VanR VFG1389 Protein 3e-25 41