Gene Information

Name : serS (CLH_0018)
Accession : YP_001919477.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 17662 - 18939 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAGAATAAGAAACAATCCGGAAGAGATAAAAAAGCTATTATCAAATAGAGGAGAAGACTTTGACGT
AGCAGTTATAGATGAAATTGTAACTTTAGATGAAGAAAGAAGAAAAATATTAGTTGAAGTTGAAAGCTTAAAGGGTAAAA
GAAATCAAGTTTCAGCAGAAATACCTAAGCTAAAAAAAGCTGGTGAAGATGTTACTCAAATAATGAATGATATGAGAAAA
CTAGGAGAAGAAATTAAAAATTTTGATACTAGAGTAAATGAGATAAATGAAAGAATAGAATACATAATGCTTAGAATCCC
TAATATTCCAAATCCAGAAGTTCCAGATGGAGAAACTGATGAAGATAATGTTGAAATTAAAAAATGGGGAGAGCCTACTA
AATTTACTTTTGAACCTAAAGCTCACTGGGATTTAGGAACTGATCTTAATATCTTAGATTTTGAAAGAGGCGGAAAGGTA
GCTGGATCTAGATTTACAGTATACAAAGGATTAGGAGCTAGATTAGAAAGATCAATAATAAACTACTTCCTAGATAAACA
CACTACTGAAAATGGATATACTGAAATATTACCACCTTACATGGTTAATAGAGATAGTATGACAGGAACTGGTCAATTAC
CTAAATTTGAAGAAGATGCATTTAAAGTAGAAAATAATGGATATTTCTTAATACCAACAGCAGAAGTACCAGTTACGAAT
ATGTATAGAAATGAAGTTTTAAGTGGTGATATTCTACCAATAAAACATGCAGCATATTCAGCTTGTTTTAGAGCAGAAGC
AGGATCAGCTGGTAGAGATACTAGAGGTCTTGTAAGACAACATCAGTTCAATAAAGTAGAATTAGTTAAGTTCTGTAAAC
CAGAAGATTCTTATGCTGAATTAGATAAATTAGTAGAAGATGCTGAATCAGTTTTACAAGGATTGGGATTACCTTATAGA
ATAGTTAGAATATGTAAGGGTGATTTAGGATTTACTGCAGCATTAAAATACGACATAGAAGTTTGGATGCCAAGTTACAA
TAGATATGTAGAAATTTCAAGTTGTTCTAATTTTGAAGATTTCCAAGCTAGAAGAGCTAATATCAAATATAGAGAAACAC
CAAAAGATAAGCCGAAGTTTATCCATACTTTAAATGGATCAGGTGTTGCAATAGGTAGAACTGTAGCAGCAGTATTAGAA
AATTATCAAAAAGAAGATGGAACAGTTGAAATTCCAGAAGCAATAAAAAGATTTATGAACGTAGATTTTATAAAATAA

Protein sequence :
MLDLKRIRNNPEEIKKLLSNRGEDFDVAVIDEIVTLDEERRKILVEVESLKGKRNQVSAEIPKLKKAGEDVTQIMNDMRK
LGEEIKNFDTRVNEINERIEYIMLRIPNIPNPEVPDGETDEDNVEIKKWGEPTKFTFEPKAHWDLGTDLNILDFERGGKV
AGSRFTVYKGLGARLERSIINYFLDKHTTENGYTEILPPYMVNRDSMTGTGQLPKFEEDAFKVENNGYFLIPTAEVPVTN
MYRNEVLSGDILPIKHAAYSACFRAEAGSAGRDTRGLVRQHQFNKVELVKFCKPEDSYAELDKLVEDAESVLQGLGLPYR
IVRICKGDLGFTAALKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIKYRETPKDKPKFIHTLNGSGVAIGRTVAAVLE
NYQKEDGTVEIPEAIKRFMNVDFIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-120 58