Gene Information

Name : panE (CLH_1071)
Accession : YP_001920465.1
Strain : Clostridium botulinum Alaska E43
Genome accession: NC_010723
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 1131312 - 1132241 bp
Length : 930 bp
Strand : +
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATTGCAATTGTTGGAGCAGGAGCTATGGGCTCACGTTATGGATATATGTTACATGAATCTGGAAATGAAGTTTT
CTTAATAGATGCATGGAAGGATCATGTAGATACTATAAATAAAGAAGGATTAACAGTTGAAGAAAATGGAGAATGCAAGA
AGGTAAAAATACCAGCAATGCTACCAGAAGATGCTAAAGAAGTTCCAGATTTAGTGATTTTATTTACTAAATCAATGGGA
TTAGAATCTATGCTGAAATCTGTAAAGAATATTTTAGGAAAACATACAAGAGTATTATGTCTATTAAATGGATTGGGTCA
TAATGAGACTATTGAAAAATATGTTGATAGTAAAAATATACTTATGGGTGTAACTTTATGGACAGCTGGATTAGCAGGTC
CTGGACATGTTGTATTAACTGGAGACGGAAGTTTAGAAGTACAAAATATTGATTCTAGTATGGAAGTAGAAGCAAGAGAA
ATTTGTGACATATTAAATCAAGCAGGATTAAAAGCTCATTATAGTGAAAATGTTATATTTTCAATATGGCGTAAAGCATG
TGTAAATGGAACTTTAAATAGTTGTTGTACAATTCTAGATTGTAATATTAAAGAGTTTGGAGAGCTAAAAGAAGCACCAC
AACTTATTCGTAATATTATAAAAGAGTTTGCTGATATTGCTGCTAAATATGGAGTAGAATTAAATGTTGAAGAAGTTGCA
AAGGGAATAGAAAAAATATATGATCCAAGCCAAGCTGGAGAACATTATCCTTCAATGCATCAAGATTTAATTCAAAATCA
TCGTCTTACAGAAATTGATTATATAAATGGATATGTATCTAGAAAAGGTAAAGAATTTAATATAAATACAGAATGTAATG
ATTTATTAACAACTATGGTTCATGCAAAAGAACAATTACTTGTTAAATAA

Protein sequence :
MKIAIVGAGAMGSRYGYMLHESGNEVFLIDAWKDHVDTINKEGLTVEENGECKKVKIPAMLPEDAKEVPDLVILFTKSMG
LESMLKSVKNILGKHTRVLCLLNGLGHNETIEKYVDSKNILMGVTLWTAGLAGPGHVVLTGDGSLEVQNIDSSMEVEARE
ICDILNQAGLKAHYSENVIFSIWRKACVNGTLNSCCTILDCNIKEFGELKEAPQLIRNIIKEFADIAAKYGVELNVEEVA
KGIEKIYDPSQAGEHYPSMHQDLIQNHRLTEIDYINGYVSRKGKEFNINTECNDLLTTMVHAKEQLLVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 1e-75 52
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 9e-76 52