Gene Information

Name : Nther_0550 (Nther_0550)
Accession : YP_001916734.1
Strain : Natranaerobius thermophilus JW/NM-WN-LF
Genome accession: NC_010718
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 573630 - 575372 bp
Length : 1743 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein mobile region; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: aoe:Clos_0586 pyruvate kinase

DNA sequence :
ATGTTAAGAAAAACCAAAATTGTGGCAACTATAGGCCCTGCTTGTGAAAACAAAGAAAGTTTAGCCAGGATGGCCCAAAA
CGGAATGGATGTCTGTCGGTTAAATTTTTCACATGGTGAACACCAGGAGCACCTGGATAGGATAAATTTAATCAGGGAAG
TTTATCAGGAATTAAAGTTTCCCCCAGCTATTTTACTTGATACCAGAGGTCCTGAAATCAGATTGGGAACTTTTGAAAAT
GGTGAAGTGGATTTGGAAAAAGGACAAGAATTTACTTTATCAACTGAAGAAATAGAAGGGGATACTACAAGAGTACATGT
AAATTATCCACAAGTCACTTCTGATATAAGTCCCGGAGATAAGGTGCTTCTTGATGATGGTTTGATTGAGCTATTAGTTA
ATGAAGTGACTGAAACAGAGGTTAAAACAGTCGTCAATAATGACGGTACCATTAAGGATAATAAAGGTGTCAATTTACCA
GGTGTGACTCTATCTTTACCAGCTATGACTGACAAAGACCAACAAGATATTTTATTTGGTATCGAAAACCAGGTGGATTT
TATTGCAGCTTCATTTATTAGAAAGCCAGAAGATGTTTTAGAAATTAGAAAATTCCTTGAAGAACATGGTTCAGATATTC
CCGTAATATCAAAAATTGAGAATAAAGAAGGTGTTGAAAATTTAGAAAGAATCTTAGAAGTTTCCGATGGCCTAATGGTG
GCACGAGGAGACCTGGGTGTTGATATACCACCAGAAGAAGTGCCCTTAGTGCAAAAAAGAATGATTAACAGATGTAATGA
TGAAGGTAAGCCTGTTATAACAGCTACACAAATGCTAGAGTCCATGACGGAAAACCCACGCCCAACTAGGGCAGAAGCCA
GCGACGTTGCTAATGCTATCATAGACGGAACTGATGCGGTTATGCTTAGTGGAGAAACGGCTGCTGGAGCTTACCCCGTG
GAATCGGTAAGTACTATGGCAAATATAGCAAAAAGTACGGAGAGGGAGCTATCTAGAAAACCACAAGAAGTTACCGCTAA
AGACACTGGTATGACCGAAGCTATTGGGTACTCCACCTGTCAGATAGCAGGCCAATTAGAAGCTAATGCCATATTAACAG
CTACCCAATCTGGGTATACGGCAAGAATGGTTGCCAAATACAAACCAAAAGCGCCAATTGTGGCAGTGACGCCAATTGAA
AAAGTTGCCAGGAGATTATCTTTATCATGGGGTGTTTATCCAATAACCTGTGACCCTTCAGAAACAACAGATGAAATGTT
TCAGGAAGCAATTCAAACAGCCCTGATAACTCAATATATTAGTGAAGGGGACCTTATTGTTATAACAGCAGGAATTCCAG
TAGGAGTTTCGGGAACAACTAACTTAATTAGAGTACATACTGTGGGAGAAATCTTAGTTTCAGGTGCAGGAATCGGGAAA
AAACCGGCAACTGGCAAAGTGGTCAAAGTAGAAGATAGCAATGATTTATCTAAAATTTCTAGTGGTGATATAGTAGTGTT
GCGGGGTACTACAGATGAAATGGTTCCTCATCTGGCTCAGGTTAGTGGTCTTGTTGCCGAAGAAGGTGGTTACACATCAC
CAAGTGCAATTGTAGGACTGGATCTAGGATTACCTGTTATTGTTGGTGCTGAAGGAGCTTTAGAAAAACTGGCAGATGGT
GATCAGGTTACTATAGATCCTTTACGAGGTTTTGTCTATAAAGGGCAAGCAACCATATTGTAA

Protein sequence :
MLRKTKIVATIGPACENKESLARMAQNGMDVCRLNFSHGEHQEHLDRINLIREVYQELKFPPAILLDTRGPEIRLGTFEN
GEVDLEKGQEFTLSTEEIEGDTTRVHVNYPQVTSDISPGDKVLLDDGLIELLVNEVTETEVKTVVNNDGTIKDNKGVNLP
GVTLSLPAMTDKDQQDILFGIENQVDFIAASFIRKPEDVLEIRKFLEEHGSDIPVISKIENKEGVENLERILEVSDGLMV
ARGDLGVDIPPEEVPLVQKRMINRCNDEGKPVITATQMLESMTENPRPTRAEASDVANAIIDGTDAVMLSGETAAGAYPV
ESVSTMANIAKSTERELSRKPQEVTAKDTGMTEAIGYSTCQIAGQLEANAILTATQSGYTARMVAKYKPKAPIVAVTPIE
KVARRLSLSWGVYPITCDPSETTDEMFQEAIQTALITQYISEGDLIVITAGIPVGVSGTTNLIRVHTVGEILVSGAGIGK
KPATGKVVKVEDSNDLSKISSGDIVVLRGTTDEMVPHLAQVSGLVAEEGGYTSPSAIVGLDLGLPVIVGAEGALEKLADG
DQVTIDPLRGFVYKGQATIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-91 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-91 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-91 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-91 51
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-54 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nther_0550 YP_001916734.1 pyruvate kinase VFG0479 Protein 9e-92 51