Gene Information

Name : Nther_2588 (Nther_2588)
Accession : YP_001918732.1
Strain : Natranaerobius thermophilus JW/NM-WN-LF
Genome accession: NC_010718
Putative virulence/resistance : Resistance
Product : CopY family transcriptional repressor
Function : -
COG functional category : K : Transcription
COG ID : COG3682
EC number : -
Position : 2777996 - 2778505 bp
Length : 510 bp
Strand : -
Note : PFAM: Penicillinase repressor; KEGG: ckl:CKL_2236 transcriptional regulator

DNA sequence : 
GTGGTTAAAAAAACTAATAAAATATCCGATTCCGAATGGGAAGTCATGGAGGTTTTGTGGGATGATTCCCCAATCCCTTC
TAGTGCTATTATAGAAAGATTACAACCTCAAACAGACTGGAAACCCAAGACTATTCACACCTTGATTAGTAGATTAGTAA
AAAAAGGTGTTGTTGGGGTAGAGAAAAATACTACACGTTACTTGTACTATCCTTTGCTGTCGAAAGAGGAGTGTAGGCTT
ACGGAAACAGAAACTTTTTTAGAAAAAGTATATAATGGATCAGTTTCTATGTTAGTGGCAAACTTTATTAAACAGGACAG
ATTATCACAACAAGAGATAAATGAACTTAAAAAACTTTTGGATGACGATACAGAGGGTGAAGCCCGAGAGGATAACAGTA
AAGACCAAAATGGTCATGTTGTGTATGAAGGACATGATGATTGTAAAGGTGCTGACCGCCATGATGAGTGTGAAGGGCAT
AAAGGCCATGATGAGCTAGGGGGAAATTGA

Protein sequence : 
MVKKTNKISDSEWEVMEVLWDDSPIPSSAIIERLQPQTDWKPKTIHTLISRLVKKGVVGVEKNTTRYLYYPLLSKEECRL
TETETFLEKVYNGSVSMLVANFIKQDRLSQQEINELKKLLDDDTEGEAREDNSKDQNGHVVYEGHDDCKGADRHDECEGH
KGHDELGGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mecI NP_373280.1 methicillin resistance regulatory protein Not tested Type-II SCCmec Protein 7e-24 43
mecI YP_190060.1 methicillin-resistance regulatory protein MecI Not tested Type-II SCCmec Protein 7e-24 43
mecI BAA82218.1 methicillin resistance protein MecI Not tested Type-II SCCmec Protein 5e-24 43
mecI NP_370567.1 methicillin resistance regulatory protein Not tested Type-II SCCmec Protein 2e-23 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nther_2588 YP_001918732.1 CopY family transcriptional repressor NC_002745.1122814.p0 Protein 2e-24 43
Nther_2588 YP_001918732.1 CopY family transcriptional repressor NC_009782.5560220.p0 Protein 6e-24 42
Nther_2588 YP_001918732.1 CopY family transcriptional repressor NC_002758.1120003.p0 Protein 6e-24 42