Gene Information

Name : Nther_0146 (Nther_0146)
Accession : YP_001916333.1
Strain : Natranaerobius thermophilus JW/NM-WN-LF
Genome accession: NC_010718
Putative virulence/resistance : Virulence
Product : ATPase AAA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 169117 - 171561 bp
Length : 2445 bp
Strand : +
Note : PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase

DNA sequence :
ATGTTTGCTAGATTTACTCAAAGAGCCCAAAAAGTCATGGCTCTATCACAAGATGAGGCGAAAAGACTAAATCATAATTA
TATAGGCACTGAACATTTACTACTGGGTCTTATTAGAGAAGGTGAAGGAATTGCTGCCCAGACCTTCAAGAACTTAGGAG
TTGATTTGGAAGAAGTTAGAGAAGCTGTGGAGAATTTAGTACAACCGGGTGAAGAACAAGTTAGTGGAAATGTGGGCTAT
ACACCCAGGGTCAAAACAGTAATTGAACTATCTATGGAAGAGGCACGGCGAATGGGTCACAACTATATAGGAACCGAGCA
CTTATTGTTGGGATTAGTTAAAGAAGGAGAAGGTATAGCCGCTAAGGTACTTCAAGAATTAGGTGTTGACTTAGATAAAG
CCCGGGAAGAAGTGCTAAAAATAATTGGTGGTAGTCAGCAGCCAAAAGGTCAAGCCAATTTTGGTCAGGCTCAAAATCCC
AAAATGGCAAATAGAGACAAAACACCTACTTTAGATAATTTTGGAAGAGACCTGACTAAACTAGCTGAAGAAGGCAAACT
AGATCCGGTGATTGGACGTAAAAAGGAAATTGAACGGGTTATCCAGGTATTAAGCAGAAGGACAAAGAATAATCCTTGTT
TAATAGGTGAACCAGGAGTAGGTAAAACTGCTATTGCTGAAGGTTTAGCCCAAAAGATAATTGAAGGTGAGGTACCCAAG
ATACTCGAAAACAAACGAGTTGTCACTCTTGAATTGTCTGCAGTGGTTGCAGGAACAAAATATAGAGGTGAGTTTGAGGA
AAGATTACGTAAATTGATTGATGAATTAACTGATAGTGGTGAAGTTATTATCTTCATTGACGAAATCCACACTATGATTG
GCGCAGGTGCCGCTGAGGGAGCTATCGATGCTTCAAATATTCTCAAACCAGCTCTAGCAAAAGGGGAACTACAATGCATA
GGTGCAACTACCCTTGATGAATATCGAAAATATATTGAAAAAGATTCGGCCCTAGAGCGTCGTTTCCAGCCAGTTACCGT
TGATGAACCTAGTAAAGAAGCAACTGTTGAAATACTTAAAGGTTTAAGAGATCGTTATGAAGCTCATCATAGAGTTCAAA
TAACAGATGACGCCATTGAAGCTAGTGTGAAAATGTCAGACAGGTATATTACTGATAGATATTTACCTGACAAAGCTATA
GATTTAATTGATGAAGCTGCTTCTAATGTTAAACTTAAAACTAATACTGCACCGCCAGATATGAGGAAACTGGAAGAAGA
TCTTGAGGAAATAGAAAAAGAAAAAGAAGCTGCAGTTAAAAGTCAAGATTTTGAACAGGCAGCCAAATTAAGGGATAAAG
AACAAGAAATTAAAAAAGAGTTAGAAGATATGGAAAAAAGCTGGGAGAAAAAACAGTTGTCCGACGAAGCTCAAGTAACT
GAGGAGGATATAGCTAGAATTGTGTCGGATTGGACTGGAATACCTGTAAAGCGCTTGGCCCAGGAAGAAACCGAACGTCT
GTTGAATATGGAAGACGCTCTCCACCAACGAGTTGTAGGTCAAGAAGAGGCGGTCCAGTCGGTATCAAATGCTATTAGAA
GAGCACGCTCTGGTCTAAAAGATCCCAAAAGACCTATTGGCTCTTTTATATTCCTTGGGCCTACAGGGGTAGGAAAAACT
GAACTTGCCAGAGCTCTGGCTGATGTGTTATTTGGCGATGAAGATGCTATGATTAGATTAGATATGTCAGAGTATATGGA
AAAGCACACGGTTTCGAGACTACTAGGGTCACCACCGGGATACGTAGGCCACGAAGAATCTGGACAGCTAACGGAAAAAG
TTCGTCGCCGCCCTTATTCGGTTATTCTACTTGATGAGATAGAAAAGGCCCATCCAGAAGTCTTTAATACATTGTTGCAA
GTTCTAGAAGATGGTCGCTTAACTGACGCTAAAGGTAGAACTGTAGATTTTAGAAATACTGTTATAATTATGACCTCCAA
TGTAGGAGCAAACTTAATTAGAAATGAAAGCAAGGTAGGTTTCAAACCTCAAACCAGTGAAGATTCATATAAAGAAATGA
AAGATAATGTTATGAGTGAACTTAAGAACTCATTCCGACCAGAGTTTTTAAATCGAGTAGATGAAGTAATCGTTTTCCAT
GCACTTGAAAAAGAACATTTATCTGACATTGTGGAACTAATGCTAGAAGAATTGAAGGAAAGAATGGCCGAATTTAACAT
GAACTTAGAGTTTACGGAAGAGTCTAAAAAACATTTGGCAGAGCAGGGCTATGACCCTACCTACGGAGCCCGTCCTTTAC
GCCGTGTAATTCAAAAGCAAGTAGAAGATGTCTTATCTGAGAAAATGCTAAGCGGCGAGTTTGCCCACGGTGAAACAGTT
GTTATCGATGCCGAAGACAATGAACTAAGCTTTAAAAAGAAGTAA

Protein sequence :
MFARFTQRAQKVMALSQDEAKRLNHNYIGTEHLLLGLIREGEGIAAQTFKNLGVDLEEVREAVENLVQPGEEQVSGNVGY
TPRVKTVIELSMEEARRMGHNYIGTEHLLLGLVKEGEGIAAKVLQELGVDLDKAREEVLKIIGGSQQPKGQANFGQAQNP
KMANRDKTPTLDNFGRDLTKLAEEGKLDPVIGRKKEIERVIQVLSRRTKNNPCLIGEPGVGKTAIAEGLAQKIIEGEVPK
ILENKRVVTLELSAVVAGTKYRGEFEERLRKLIDELTDSGEVIIFIDEIHTMIGAGAAEGAIDASNILKPALAKGELQCI
GATTLDEYRKYIEKDSALERRFQPVTVDEPSKEATVEILKGLRDRYEAHHRVQITDDAIEASVKMSDRYITDRYLPDKAI
DLIDEAASNVKLKTNTAPPDMRKLEEDLEEIEKEKEAAVKSQDFEQAAKLRDKEQEIKKELEDMEKSWEKKQLSDEAQVT
EEDIARIVSDWTGIPVKRLAQEETERLLNMEDALHQRVVGQEEAVQSVSNAIRRARSGLKDPKRPIGSFIFLGPTGVGKT
ELARALADVLFGDEDAMIRLDMSEYMEKHTVSRLLGSPPGYVGHEESGQLTEKVRRRPYSVILLDEIEKAHPEVFNTLLQ
VLEDGRLTDAKGRTVDFRNTVIIMTSNVGANLIRNESKVGFKPQTSEDSYKEMKDNVMSELKNSFRPEFLNRVDEVIVFH
ALEKEHLSDIVELMLEELKERMAEFNMNLEFTEESKKHLAEQGYDPTYGARPLRRVIQKQVEDVLSEKMLSGEFAHGETV
VIDAEDNELSFKKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nther_0146 YP_001916333.1 ATPase AAA VFG0079 Protein 0.0 63
Nther_0146 YP_001916333.1 ATPase AAA VFG0080 Protein 5e-163 53