Gene Information

Name : Nther_1394 (Nther_1394)
Accession : YP_001917565.1
Strain : Natranaerobius thermophilus JW/NM-WN-LF
Genome accession: NC_010718
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1466044 - 1467363 bp
Length : 1320 bp
Strand : +
Note : KEGG: hmo:HM1_2224 flagellar protein export ATPase FliI, putative; TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/be

DNA sequence :
GTGGCAACTGATGGTGTAGACTTAGATAAACTTTCTCAAACAATAAGGAATAGTAACACTTTACCTTTACAAGGAGAAGT
CACCAGAGTTGTAGGGTTAACTGTTGAGGCCCGAGGCCCAGGGGCTAAAATCGGTGATTTGTGCCTTATCAGAAGTGATG
ATCAGGAGATTGAGTGTGAAGTTGTAGGTTTCAATGATGGAAAAATACTATTGATGCCCCTTGGTAATTTAAACAATGTG
GCACCGGGTAATAAAGTGATTACTTCTCGAGAGAATTTGTCAGTACCTGTAGGTCCTGGTTTGGTTGGTAGAGTATTAGA
TGGTCTAGGTCGCCCTATGGATGGAAAGGGCCCCCTTACTAATACAAAATGTCGTTATCCTATGGAAAACACTCCCCCCG
CTCCCCTTGACCGCAGTAGGATACAAAAACCTATTCAAACTGGTATTAAAGCTATTGATGGGGTTTTGACAATTGGAAAA
GGGCAGCGGATGGGAATTTTTTCAGGGTCTGGAGTAGGTAAAAGTACACTCCTAGGTATGATTGCAAGAAATACTTCTGC
CTCTGTCAATGTAATTGGTTTAATAGGTGAACGGGGCAGAGAAGTTCGTGAATTTATAGAAAAAGATTTAGGAGAAGAAG
GATTACAACGAAGTGTTATTGTGGTTGCCACCTCTGACCAACCCGCTCTTTTGAGAATCAAGGGAGCGATGACTGCAACT
GCTATTGCAGAATATTTCCGTGACTGTGGAAATGATGTCATGCTAATGATGGACTCTGTAACCAGGTTTGCTACTGCCAA
ACGGGAAGTTGGACTGGCAACAGGTGAGCCACCGGCTACAAGAGGGTTTCCACCTTCTGTTTTTGCAATGTTGCCCCAGC
TGTTAGAAAGGTCTGGTACTTCTGATAAAGGGAGTGTTACCGGTTTATATACTGTATTGGTTGATGGAGATGATATGGAC
GAGCCCGTATCCGATACCGTTCGGGGAGTGCTAGATGGTCATATTGTTCTTAGCAGAAAGCTGGCCATGCAAAATCATTA
TCCGGCCATTGATATACTACAGAGCATTTCACGGGTGATGGTGGATATTACTGATACTCAACATCAAAAAGCGGCTGCCA
AAATTAGTTCAGCTCTGGCAGCCTATGAAGAGGCCCGAGATTTGATTGAAATCGGGGCTTATAAAAAGGGGAGCAATCCC
AAGGTTGACTGGGCGATGGAGCTAATTGACGATTTAAATGAGTTTTTACGCCAGGAAATCACAGAAAAAACTACTCTGGA
TGAAACCATCAATAAACTAAAGAAGTTTTTAGATGATTAA

Protein sequence :
MATDGVDLDKLSQTIRNSNTLPLQGEVTRVVGLTVEARGPGAKIGDLCLIRSDDQEIECEVVGFNDGKILLMPLGNLNNV
APGNKVITSRENLSVPVGPGLVGRVLDGLGRPMDGKGPLTNTKCRYPMENTPPAPLDRSRIQKPIQTGIKAIDGVLTIGK
GQRMGIFSGSGVGKSTLLGMIARNTSASVNVIGLIGERGREVREFIEKDLGEEGLQRSVIVVATSDQPALLRIKGAMTAT
AIAEYFRDCGNDVMLMMDSVTRFATAKREVGLATGEPPATRGFPPSVFAMLPQLLERSGTSDKGSVTGLYTVLVDGDDMD
EPVSDTVRGVLDGHIVLSRKLAMQNHYPAIDILQSISRVMVDITDTQHQKAAAKISSALAAYEEARDLIEIGAYKKGSNP
KVDWAMELIDDLNEFLRQEITEKTTLDETINKLKKFLDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-96 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-84 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-84 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-84 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-84 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-84 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-84 49
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-85 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-83 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-83 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-77 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-77 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-77 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 7e-77 47
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-77 47
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-77 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-72 47
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-72 47
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-73 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-75 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 9e-75 45
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-75 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-74 45
escN AAC31513.1 L0034 Virulence LEE Protein 2e-74 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-74 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 7e-75 45
escN AAK26715.1 EscN Virulence LEE Protein 1e-74 45
escN AAL57542.1 EscN Virulence LEE Protein 1e-74 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-74 45
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-74 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-74 45
escN AAC38383.1 EscN Virulence LEE Protein 2e-74 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-76 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-76 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 8e-81 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 5e-76 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-69 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-67 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-70 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-71 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-71 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-66 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-66 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 8e-66 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 4e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 2e-102 52
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 1e-96 52
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 1e-93 51
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 8e-78 48
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 6e-95 47
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 6e-93 47
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 1e-84 47
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 3e-87 46
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 1e-74 45
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 1e-74 45
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG1008 Protein 3e-63 43
Nther_1394 YP_001917565.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 8e-65 41