Gene Information

Name : HPSH_04305 (HPSH_04305)
Accession : YP_001910326.1
Strain : Helicobacter pylori Shi470
Genome accession: NC_010698
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein Cag beta
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3505
EC number : -
Position : 839971 - 842217 bp
Length : 2247 bp
Strand : +
Note : COG3505 Type IV secretory pathway, VirD4 components

DNA sequence :
ATGGAAGACTTTTTATATAACACCTTATATTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTTCTCTACAAATTCATAAAAGCTCAAAAAAAGGCTTTTAAAGATAAAGCTAACCAACCTCAAAAGAAAA
AAAACTTTAAAGAAATCATTATAGAGGGGCTGAAAGAAAGAGTTAAAACCTTTGGCTTTTGGTTACAAGCTATACTATTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATTCTCTTAGGTAATTTTTATGATGACAATAAATTGCCTGA
GAGTGATGATGATCTTTTTGATATATGGATCTATGCGATACAAGATTTTCCTGCATACTATTTTAAGGCGCTTTGTTTTA
GTTCACTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAGAGCGAAGAAAAAATGATCAAAGCTAAACTTATCACACCCAATAATAAAAAACGCGCCTTTGACAAACGAG
AGGTTATTGTAGGCAGGCGTGGTTTAGGGGATTTTATCGCTTATGCAGGACAGGCGTTCATTGGCTTGATCGCTCCCACT
AGAAGCGGTAAGGGTGTGGGTTTCATCATGCCCAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGACCCTAAGGC
TGACACTATGGAAACTTGCGGAAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTATATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAACGATGTGGTTTTGACTGAAGACATACTCTCTCAAATT
GACACACGCCTAAAAGGTCATGGGATGGTGGCTAGTGGGGGGGATTTTTCCACTCAAATCTTTGGATTGGCTAAGTTGGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTTTTTAGCAATCAGGCGCGAAATCTTTTTGTCATTAATTGCAATATTT
ATAGGGATCTCATGTGGACTAAAAAGGGGCTTGAATTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCCACGATG
TTTTTCATAGGTTCTATGGCGAGCGGTATCAATTTGATTGATGAAAACACAAACATGGAAAAAGTTGTGTCTCTGATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGACAATCTAAGAGTGCTTAGTCCTGCTACTAGAAACATGTGGAACAATT
TCAAAACAATGGGTGGTGCTAAAGAAACTTACAGCTCTGTTCAAGGGGTCTATACCTCAGCGTTTGCGCCTTACAATAAT
GCTATGATTAGGAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTGAGGATTGATGAAGTGAGTATTGGCGTGAT
CGCTAACCCTAAAGAAAGCACTATTGTTGGGCCGATATTAGAGCTGTTTTTCAATGTGATGATTTATAGCAACCTTATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGTTGTTTGATGCTTATGGATGAGTTCACGCTCTGTGGCTATTTAGAAACC
TTTGTGAAAGCGGTAGGGATTATGGCAGAATACAACATGCGCCCTGCCTTTGTGTTTCAAAGTAAGGCGCAACTAGAGAA
TGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTAAATATGTATTATGGGATTA
ACAACGATAACTACTATGAACATTTTGAAAAACTTTCTAAGGTGTTGGGGAAATACACAAGGCAAGACGTGAGTCGAAGC
ATTGATGATAATACAGGTAAGACCAACACTTCTATCAGCAACAAAGAGCGGTTTTTGATGACCCCTGATGAATTGATGAC
CATGGGCGATGAGCTTATCATTTTAGAAAACACGCTCAAACCCATCAAATGCCACAAGGCACTCTACTATGATGATCCGT
TCTTCACCGATGAACTCATCAAAGTGAGTCCAAGCTTGAGCAAGAAATACAAATTGGGGAAAGTGCCTAATCAAGCAACT
TTCTATGATGATTTGCAAGCCGCTAAAACTAGAGGCGAATTGAGCTATGACAAGTCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA

Protein sequence :
MEDFLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIIIEGLKERVKTFGFWLQAILL
LSYSFITSGLFFLILLGNFYDDNKLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWESEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVYIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDENTNMEKVVSLMEFFGGEEDKSGDNLRVLSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 98
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPSH_04305 YP_001910326.1 cag pathogenicity island protein Cag beta VFG0284 Protein 0.0 99