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Name : HPSH_04285 (HPSH_04285) Accession : YP_001910322.1 Strain : Helicobacter pylori Shi470 Genome accession: NC_010698 Putative virulence/resistance : Virulence Product : cag pathogenicity island protein CagY Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG2948 EC number : - Position : 832665 - 838229 bp Length : 5565 bp Strand : + Note : COG2948 Type IV secretory pathway, VirB10 components DNA sequence : ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAAC AATAAAAGCCAATCACTTTGAAGATTCTTCAAAAGAATCCAAAGAAAGCTCAAATCATCATCTTGACAACTCCACAGAAA CTAAAACCAATTTTGATGAATACAAGTCAGAAGAAACCCAAACTCAAATGGATTCTGGAGGTAATGAAACTTCAGAATCT AGCAATCTAGCAGACAAGTTATTCAAAAAAGCCAGAAAATTAGTTGATAATAAAAGACCTTTCACTCAGCAAAAGAATTT AGATGAAGAAATCCAAGAACCGAACGAAGAAGACGATCAAGAAAATAATGGGTATCAAGAAGAAATTCAAATGGATTTAA TTGATGATGAAACTTCTAAAAAAACCCAACAACATTCACCCCAAGATCTATCCAATGAAGAAACAATAAAAGCCAATCAC TTTGAAGATTCTTCAGAAGAATCCAAAGAAAACTCAGATCATCATCTTGACAACTCCACAGAAACTAAAACCAATTTTGA TGGAGAAAAGTCAGAAGAAACCCAAACTCAAATGGATTCTGGAGGTAATGAAACTTCAGAATCTAGCAATCTAGCAGACA AGTTATTCAAAAAAGCCAGAAAATTAGTTGATAATAAAAGACCTTTCACTCAGCAAAAGAATTTAGATGAAGAAATCCAA GAACCGAACGAAGAAGACGATCAAGAAAATAATGGGTATCAAGAAGAAATTCAAATGGATTTAATTGATGATGAAACTTC TAAAAAAACCCAACAACATTCACCCCAAGATCTATCCAATGAAGAAACAATAAAAGCCAATCACTTTGAAGATTCTTCAA AAGAATCCAAAGAAAACTCAGATCATCATCTTGACAACTCCACAGAAACTAAAACCAATTTTGATGGAGAAAAGTCAGAA GAAATAACTAACGATTCTAACGATCAAGAGATTATCAAAGGAAGCAAAAAGAAATACATTATTGGTGGCATTGTAGTCGC TGTTCTTATCGTGATTATTTTATTTTCTAGAAGCATTTTTCACTATTTCATACCTTTGGAAGATAAAAGCTCTCGTTTTA GCAAAGACAGGAATCTTTATGTCAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCTGAAAGAACGGAATGAA AAAGGCAATATGATCGATAAGAATCTTTTCTTCAATGACGATCCCAATAGAACCTTATACAACTATTTGAATATTGCAGA AATTGAGGACAAAAACCCATTGAGAGCCTTTTATGAATGTATTAGTAATGGTGGTAACTATGAAGAATGTTTGAAGCTTA TCAAAGACAAAAAACTTCAAGATCAAATGAAAAAGACTTTAGAGGCTTATAATGACTGCATCAAAAATGCCAAAACTGAA GAAGAAAGGATCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTACTGAACCAACAAAAAGTTCAAGT GGCACTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCCTAAAACTCATAAATGACCCTGAGATTA GAGAGAAATTCCGTAAGGAATTAGAGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAAAAACGCCAAAACAGAA GCTGAGAAAAACGAATGCTTGAAAGGCTTGTCTAAGGAAGCTATAGAAAGATTGAAACAGCAAGCGCTAGATTGTTTGAA AAACGCTAAAACCGATGAAGAACGAAAAAAGTGTTTGAAAAATATTCCCCAAGACTTGCAAAAAGAACTACTAGCTGATA TGAGCGTCAAGGCTTACAAGGATTGCGTATCAAAAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACTCACG CCTGAAGCGAAAAAAAAGTTAGAACAACAGGTTCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAAAAAGTG TTTGAAAGATCTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGCGTTAAAGCTTATAAAGACTGCGTATCTC AAGCCAGAACTGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCC AAAGAGAGCGTTAAAGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAATTACT CACGCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTACCTGGATTGCGTATCTCAAGCCAAAA CTGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGAAAGCTTTTAGAGCAACAAGCGCTAGATTGT TTGAAAAACGCTAAAACCGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTCCCTAAAGACTTGCAGAAAAAGGTTTTAGC TAAAGAGAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAAAAATTAC TCACCCCTGAAGCGAAAAAACTTTTAGAAGAAGCTAAAGAGAGTCTTAAAGCTTATAAAGACTGCGTATCTCAAGCCAGA ACTGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGCTAAAGAGAG CGTTAAGGCTTATTTGGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTGCTCACCCCTG AAGCGAGAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTACCTGGATTGCGTATCTCAAGCCAAAACTGAAGCT GAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAACAACAAGCGCTAGATTGTTTGAAAAA CGCTAAAACCGAAGCTGAGAAAAAAAGGTGCGTCAAAGATCTTCCTAAAGACTTGCAGAAAAAGGTTTTAGCCAAAGAGA GTCTTAAGGCTTATAAAGACTGTGTTTCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACTCACGCCT GAAGCGAAAAAACTTTTAGAAGAAGCTAAAGAGAGTCTTAAAGCTTATAAAGACTGCGTTTCAAGAGCTAGGAATGAAAA AGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGAAAACTTTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTT ATTTGGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGAAAA CTTTTAGAAGAAGCTAAAGAGAGTCTTAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGAAAAGC TTGTGAGAAATTGCTCACGCCTGAAGCGAGAAAACTCTTAGAGCAAGAAGTTAAGAAGAGCGTTAAGGCTTATTTGGACT GCGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGAAAATTTTTAGCG AAGCAAGCGCTAAGTTGTTTGGAAAAAGCTAGAAATGAAGAAGAAAGAAAAGCATGTCTTAAAAATATCCCTAAAGACTT ACAGAAAAATGTTTTAGCTAAAGAGAGTCTTAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGAA AAGCTTGTGAGAAATTGCTCACCCCTGAAGCGAGAAAACTCTTAGAGCAAGAAGTTAAGAATAGCGTTAAGGCTTATTTG GACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAGAAAATTTTT AGCGAAAGAGCTCCAACAAAAAGATAAAGCGATCAAAGATTGCTTGAAAAACGCCGATCCTAACGACAGAGCAGCTATTA TGAAGTGTTTGGATGGTTTGAGCGATGAAGAGAAGCTCAAATACCTGCAAGAAGCTAGAGAAAAGGCTGTCTTGGATTGT TTGAAAACGGCTAAGACCGATGAAGAAAAAAGGAAATGTCAAAACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAA AAGGGCACAAAGCAAACAAAATCAATTGAGTAAAACAGAAAGATTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATG ACCCTACTGATCAAGAAGCCATAGAGCAATGTTTAGAAGGCTTGAGCGATAGTGAAAGGGCGCTAATTCTAGGAATTAAA CGACAAGCTGATGAAGTGGATCTGATTTATAGCGATCTAAGAAACCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTA TCCATTGTTGCCAATGGATTTCAAAAATGGTGGCGATATTGCCACTATTAACGCCACTAATGTTGATGCGGACAAAATAG CTAGCGATAATCCTATTTATGCTTCCATAGAGCCTGACATTACTAAGCAATACGAAACAGAAAAAACCATTAAGGATAAG AATTTAGAAGCTAAATTAGCTAAGGCTTTAGGTGGCAATAAAAAAGATGACGATAAAGAAAAAAGTAAAAAATCCACAGC AGAAGCTAGAGTAGAAAGCAATAAGATAGACAAAGATGTCGCAGAAACTGCCAAAAATATCAGTGAAATCGCTCTTAAGA ACAAAAAAGAAAAGAGTGGGGAATTTGTAGATGAAAATGGTAATCCCATTGATGACAAAAAGAAAACAGAAAAACAAGAT GAAACAAGCCCTGTCAAACAGGCCTTTATAGGCAAGAGTGATCCCACATTTGTTTTAGCGCAATACACCCCTATTGAAAT CACTCTGACTTCTAAAGTAGATGCCACTCTCACAGGTATAGTGAGTGGGGTTGTGGCCAAAGATGTATGGAACATGAACG GCACCATGATCTTACTAGACAAAGGCACTAAGGTGTATGGGAATTATCAAAGCGTGAAAGGTGGCACACCCATTATGACA CGCTTAATGATAGTCTTCACTAAAGCCATTACGCCTGATGGTGTGATAATACCTCTAGCAAACGCTCAAGCAGCAGGCAT GCTGGGTGAAGCAGGGGTAGATGGCTATGTGAATAATCACTTTATGAAGCGCATAGGCTTTGCTGTGGTAGCAAGCGTGG TTAATAGCTTCTTGCAAACTGCGCCTATCATAGCTCTAGATAAACTCATAGGCCTTGGCAAAGGTAGAAGTGAAAGGACA CCTGAATTTAATTACGCTTTGGGTCAAGCTATCAATGGTAGTATGCAAAGTTCAGCTCAGATGTCTAATCAAATTCTAGG GCAACTGATGAATATCCCCCCAAGTTTTTACAAAAATGAGGGCGATAGTATTAAAATTCTCACAATGGACGATATTGATT TTAGTGGCGTATATGATGTTAAAATTACCAACAAATCTGTGGTAGATGAAATTATCAAACAAAGCACTAAAACTTTGTCT AGAGAGCATGAAGAAATCACCACAAGCCCCAAAGGTGGCAATTAA Protein sequence : MNEENDKLETSKKTQQHSPQDLSNEETIKANHFEDSSKESKESSNHHLDNSTETKTNFDEYKSEETQTQMDSGGNETSES SNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEDDQENNGYQEEIQMDLIDDETSKKTQQHSPQDLSNEETIKANH FEDSSEESKENSDHHLDNSTETKTNFDGEKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQ EPNEEDDQENNGYQEEIQMDLIDDETSKKTQQHSPQDLSNEETIKANHFEDSSKESKENSDHHLDNSTETKTNFDGEKSE EITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFIPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNE KGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTE EERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTE AEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERKKCLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKKECEKLLT PEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESVKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEA KESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEQQALDC LKNAKTEAEKKRCVKDLPKDLQKKVLAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQAR TEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSRARNEKEKQECEKLLTPEARKKLEEAKKSVKAYLDCVSQAKTEA EKKECEKLLTPEAKKLLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESLKAYKDCVSRARNEKEKKECEKLLTP EAKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEARKLLEEAKKSVKAYLDCVSRARNEKEKKECEKLLTPEARK LLEEAKESLKAYKDCLSQARNEEERKACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLA KQALSCLEKARNEEERKACLKNIPKDLQKNVLAKESLKAYKDCLSQARNEEERKACEKLLTPEARKLLEQEVKNSVKAYL DCVSRARNEKEKQECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDC LKTAKTDEEKRKCQNLYSDLIQEIQNKRAQSKQNQLSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERALILGIK RQADEVDLIYSDLRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDK NLEAKLAKALGGNKKDDDKEKSKKSTAEARVESNKIDKDVAETAKNISEIALKNKKEKSGEFVDENGNPIDDKKKTEKQD ETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMT RLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVVASVVNSFLQTAPIIALDKLIGLGKGRSERT PEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLS REHEEITTSPKGGN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| HP0527 | BAD14052.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 93 |
| cag-Y | AAF80198.1 | Cag-Y | Virulence | cag PAI | Protein | 0.0 | 93 |
| HP0527 | BAD13833.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 93 |
| cagY | YP_005777271.1 | cag pathogenicity island protein Y VirB10-like protein | Virulence | cag PAI | Protein | 0.0 | 93 |
| cagY | AGC69785.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 93 |
| cagY | AGC69788.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 93 |
| cagY | AGC69789.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 93 |
| cagY | YP_005774542.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 92 |
| HP0527 | BAD13970.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 92 |
| HP0527 | BAD13998.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 92 |
| cagY | AGC69792.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 91 |
| HP0527 | NP_207323.1 | cag pathogenicity island protein (cag7) | Virulence | cag PAI | Protein | 0.0 | 90 |
| HP0527 | BAD14026.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 90 |
| HP0527 | BAD13888.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 88 |
| HP0527 | BAD13915.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 87 |
| HP0527 | BAD13860.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 87 |
| cagY | YP_005775730.1 | cag pathogenicity island protein Y VirB10-like protein | Virulence | cag PAI | Protein | 0.0 | 87 |
| HP0527 | BAD13779.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 85 |
| cagY | YP_005779063.1 | cag island protein | Virulence | cag PAI | Protein | 0.0 | 85 |
| cagY | AGC69786.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 85 |
| cagY | AGC69787.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 85 |
| orf13/14 | NP_223194.1 | cag island protein | Virulence | cag PAI | Protein | 0.0 | 82 |
| HP0527 | BAD13806.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 82 |
| HP0527 | BAD13943.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 78 |
| cagY | YP_003728737.1 | cag pathogenicity island protein Y | Virulence | cag PAI | Protein | 0.0 | 76 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| HPSH_04285 | YP_001910322.1 | cag pathogenicity island protein CagY | VFG0287 | Protein | 0.0 | 90 |
