Gene Information

Name : HPSH_04280 (HPSH_04280)
Accession : YP_001910321.1
Strain : Helicobacter pylori Shi470
Genome accession: NC_010698
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein CagX
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3504
EC number : -
Position : 831082 - 832650 bp
Length : 1569 bp
Strand : +
Note : COG3504 Type IV secretory pathway, VirB9 components

DNA sequence :
ATGGAGCAGGCATTTTTTAAAAAAATTGTTGGCTGTTTCTGTCTTGGTTATTTATTTTTATCTAGCGTAATAGAAGCAGC
AGCACCTGACATTAAAAATTTTAATCGTGGTAGGGTGAAAGTGGTGAATAAGAAGATTGCTTATTTAGGAGATGAAAAAC
CTATTACGATTTGGACTTCATTAGACAATGTTACTGTGATCCAACTTGAAAAAGATGAAACCATTTCTTACATCACAACA
GGTTTCAATAAAGGTTGGAGTATTGTGCCTAATTCTAATCATATATTCATTCAACCTAAATCGGTAAAAAGTAATCTCAT
GTTTGAAAAAGAAGCAGTGAATTTTGCTCTAATGACAAGAGATTACCAAGAATTTTTAAAAACAAAAAAACTTATCGTAG
ATGCACCTGACCCTAAAGAATTAGAAGAACAAAAAAAAGCTCTAGAAAAAGAAAAAGAAGCTAAAGAACAGGCGCAAAAA
GCGCAAAAAGATAAAAGAGAAAAAAGAAAGGAAGAGCGTGCAAAAAATAGAGCCAATTTAGAAAATCTCACTAACGCTAT
GAGTAACCCACAAAATTTGAGCAATAACAAAAATCTTAGCGAATTTATCAAGCAACAACGAGAAAATGAATTAGACCAAA
TGGAACGACTAGAGGACATGCAAGAACAGGCTCAAGCTAATGCACTCAAACAAATTGAAGAACTCAACAAGAAACAAGCT
GAAGAGACAATAAAACAAAGAGCCAAGAATAAAATCAATATTAAGACAGATAAGCCTCAAAAAAGCCCTGAGGATAACTC
CATAGAATTATCTCCTAGCGATAGCGCTTGGAGAACTAATCTTGTTGTGCGGACCAATAAGGCCTTGTATCAATTCATTT
TGAGAATAGCTCAAAAAGACAATTTTGCTTCGGCGTATCTAACAGTCAAATTAGAATACCCACAAAGACACGAAGTCTCT
AGCGTTATTGAAGGGGAGCTAAAAAAGAGAGAAGAAGCAAAGAGGCAGAGAGAATTGATTAAGCAAGAAAATCTTAACAC
CACAGCCTACATCAATAGAGTAATGATGGCGAGCAACGAACAGATTATCAACAAAGAAAAAATAAGAGAAGAAAAACAAA
AAATTATCTTAGATCAAGCAAAGGCGCTAGAGACTCAATATGTGCATAATGCATTAAAAAGAAACCCTGTGCCTAGAAAC
TACAATTACTACCAAGCACCTGAAAAACGCTCTAAACATATTATGCCCTCTGAAATTTTTGATGATGGCACATTCACTTA
TTTTGGTTTCAAAAACATCACCCTCCAACCTGCTATTTTTGTGGTTCAGCCTGATGGGAAATTAAGCATGACTGATGCCG
CTATTGATCCTAACATGACCAATTCAGGATTGAGATGGTATAGAGTTAATGAAATTGCAGAAAAGTTTAAGCTCATTAAA
GACAAAGCCCTTGTAACAGTAATAAATAAAGGCTATGGGAAAAATCCATTGACAAAAAATTACAATATCAAAAACTATGG
TGAATTGGAGCGTGTGATTAAAAAGCTCCCTCTTGTCAGAGATAAATAA

Protein sequence :
MEQAFFKKIVGCFCLGYLFLSSVIEAAAPDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITT
GFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQK
AQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQA
EETIKQRAKNKINIKTDKPQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVS
SVIEGELKKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRN
YNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIK
DKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0528 BAD13889.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005779062.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005775731.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005774541.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13944.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13861.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13834.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13807.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13780.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD13971.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 BAD14027.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03921.1 Cag8 Virulence cag PAI Protein 0.0 99
cag-X AAF80199.1 Cag-X Virulence cag PAI Protein 0.0 99
HP0528 BAD14053.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03952.1 Cag8 Virulence cag PAI Protein 0.0 99
HP0528 BAD13999.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0528 NP_207324.1 cag pathogenicity island protein (cag8) Virulence cag PAI Protein 0.0 99
HP0528 BAD13916.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cagX YP_005777272.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag8 AAR03863.1 Cag8 Virulence cag PAI Protein 0.0 99
cagX AGC69795.1 cag pathogenicity island protein X Virulence cag PAI Protein 0.0 98
cagX YP_003728736.1 cag pathogenicity island protein X Virulence cag PAI Protein 0.0 98
cag8 AAR03891.1 Cag8 Virulence cag PAI Protein 0.0 98
orf15 NP_223195.1 cag island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPSH_04280 YP_001910321.1 cag pathogenicity island protein CagX VFG0288 Protein 0.0 99