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Name : HPSH_04215 (HPSH_04215) Accession : YP_001910308.1 Strain : Helicobacter pylori Shi470 Genome accession: NC_010698 Putative virulence/resistance : Virulence Product : cag pathogenicity island protein CagA Function : - COG functional category : D : Cell cycle control, cell division, chromosome partitioning COG ID : COG1196 EC number : - Position : 819912 - 823169 bp Length : 3258 bp Strand : - Note : - DNA sequence : ATGGCTAACGAAACCATCAATCAAACAAAAAATCCAGATCAAACACCAAACCAAACGGCTTTTGATCCACAACAATTTAT CAATAATCTTCAAGTGGCTTTCATTAAAGTTGATAGCGCTGTCGCTTCATTTGATCCCGATCAAAAACCAATCGTTGATA AGAACGATAGGGATAACAGGCAAGCTTTTAATGGAATCTCGCAATTAAGGGAAGAATACGCCAATAAAGCGATCAAAAAT CCCAACAAAAAGAATCAGTATTTTTCAGACTTTATCAATAAGAGCAATGATTTGATCAACAAAGACAATCTCATTGATAC AGATTCTTCCACAAAGAGCTTTCAGAAATTTGGGCCTGAGCCTTACCAAATTTTTATGAATTGGGTGTCCCATCAAAAAG ATCCGTCTAAAATCAACACCCAAAAAATCCGAGATTTTATGGAAAATATCATACAACCCCCTATCTCTGATGATAAAGAA AAAGCGGAGTTTTTGAGGTCTGCCAAACAATCTTTTGCAGGAATTATCATAGGAAACCAAACCCGATCGGATGAAAAATT CATGGGCGTGTTTGGTGAATCTTTGGATGAATCTTTGGATGAATCTTTGGATGAATCTTTGGATGAATCTTTGGATGAAT CTTTGAGAGAGAAGCAAGAAGCAGGAAAAAATGGGGATTGGCTTGATATTTTTTTATCGTTTGTGTTTAACAAAAAACAA TCTTCCGATCTCAAAGAAACGCTCAATCAAGAGCCAAGGTCTAATGTTGAACAAAATATAGCCACTACCCCCACCCCCAT ACAAGGCTTACCGCCTGAAGCTAGGGATTTGCTTGATGAAAGGGGTGATTTTTCTAAATTCACTCTTGGTGATATGGAAA TGTTGGATGTTGAGAGGCTCAACCAGTTATTGATTCACAATAACGCTCTGTCTTCTATGCTAATGGGGAGTCATAGCAAC ATAAAACCTGAAAAAGTTTCATTGTTGTATGGGGATAATGGTGGCCCTGAAGCTAGGCATGATTGGAACGCCACCGTTGG TTATAAAAACCAACAAGGCAACAATGTGGCCACACTCATCAATGCACATCTTAAAAACAGCAGTGGGTTAATCATAGCGG GTAATGAAAATGGGATTAACAACCCTAGCTTCTATCTCTACAAAAAAGACCAACTCACAGGCTTGGAACAAGCGTTGAGT CAAGAAGAGATCCAAAACAAACTAGGTTTCATGGAATTTCTTGCACAAAACAGCGCTAGACATGTTGGATTAAATAACTT GAGCAAGGAAGAGAAAGAAAAGTTCCAAACTGAAATTGGAAATTTCCAAAAAGACCCTAAGGCTTATTTAGACACCCTAG GGAGTGATCACATTGCTTTTGTTTCTAAAAAAGACCAAAAGCATTTAGCTTTGGTTACTGAGTTTGGCAATGGGGAATTG AGCTATACCCTCAAAGATTATGGGAAAAAACCAGATAGAGCTTTAGATAGGGAGACAAAAACCACTCTTCAAGGTAACCT AAAAGATGATGGCGTGATGTTTGTCAATTATTCCAATTTCAAATACACCAACGCCTCCAAGAGTCCTAATGAGGGTATAG GCGCTACGAATGGCGTTTCCCATTTGGAAGCAAATTTTAGCAAGGTAGCTGTCTTTAATTTGCCTGATTTAAATGGTCTC GCTGTCTCTAGTTTTGCAAGGCGGAATTTAGAGGATAAACTGGCCGCTAAAGGATTGTCCGGAAAAGAATCTAATAAGAT CATCAAAGACTTTTTGAACAGCAACAAGGAATTGCTTGAAAAAGTTTTAAACTTCAATAAAGCTGTAGCTGAAGCTAAAA ATACAGGCAATTATGGCGGAGTGAAAAAAGCTCAAAAAGATCTTGAAAAATCTATAAGGAAACGAGAGCTTTTAGAGAAA GAAGTAACGAAACAATTTGAGAGCAAGAGCGGCAACAAAAATAAAATGGAAGCAAAAGCTCAAGCTAACAGCCAAAAAGA TGAGATTTTTAAGCTTATCAATGAAGGGGCTTATAAGGAAGCAAGAATCATCGCTTACGCTCAGAATCTTAAAGGCATCA GGAGGGAATTGAGGGAATTGTTTGATAAAATTGGAAATATCAACAAGAATTTGAAAGACTTTAATCAATCTTTTGATGCG CTCAAAAGTGGTAAAAATAAGGATTTCAGCAAGGTAGAAGAAACGCTAAAAGCCCTTAAAAGCTCGGTGAAAGATTTGAA TATCAATCCAGAATGGATTTCAAAAGTTGAAAACCTTAATGTAGCTTTGAATGAATTCAAAAATGGCAAAAATAAGGATT TCAGCAAGGTAACACAAGCAAAAAGCGACCTTGAAAATTCCATTAAGGATGTGCACATCAATCAACAGATAACGGATAAA GTTGACAATCTCAATCAGGCTGTATTAGTGGCTAAAGCGACAGGCGATTTTAGTGGGGTAGAGCAAGCGCTAGCCGGACT CAAAAACTTCAATGTTGGAAAAAATTCTGATAGGTCTGAACCCATTTACGCCACGATTGATGATCTCGACGGATCTTCCC CTTTGAAAAGGTATGCTAAAGTTGATGATCTCAGTAAGGTAGGGCAATCAGATAGCCCTGAACCCATTTACGCTAATCTC GGCGGATCTTCCCCTTTGAAAAGGCATGCTAAAGTTGATGATCTCAGTAAGGTAGGGCTTTCAAGGGAGCAAGAATTGAC TCAGAAAATTGGCAATCTCAATCAGGCAGTGTCAGAAGCTAAAGCAGGTTCTTTTGGCAACCTAGAACAAACGATGGATG GACTCAAAGATTCTACAAAAAAGAATGTTGTGAATCTATGGTTTGAAGGTGCAAGAAAAGTGCCTATTAGTTTGCCTAGT TCGCAAGCGAAATTGGACAATTACGCTACTAACAGCCACACACGCATTAATAGCAATGTCAAAAATGGAACAGTCAATGA AAAAGCGACCATCATGCTAACGCAAAAAAACCCTGAGTGGCTTAAGCTCGTGAATGATAAGATAGTTGCGCATAATGTGG GAAGCACTCCTTTGTCAGATTATGATAAAATTGGATTCAACCAAAAGAATATGAAAGATTACTCTGATTCGTTCAAGTTT TCCATCAAGTTGAGTAATGCCGTAAAAAACATTAAGTCTGGCTTTGTGCAATGTTTAACCGATTGCATTTCTGCAGGATC TTACAGCCCAAAGAAAGCGGAACATGGAGTTACAAAAAGTGGTTTCCAGAAATCTTAA Protein sequence : MANETINQTKNPDQTPNQTAFDPQQFINNLQVAFIKVDSAVASFDPDQKPIVDKNDRDNRQAFNGISQLREEYANKAIKN PNKKNQYFSDFINKSNDLINKDNLIDTDSSTKSFQKFGPEPYQIFMNWVSHQKDPSKINTQKIRDFMENIIQPPISDDKE KAEFLRSAKQSFAGIIIGNQTRSDEKFMGVFGESLDESLDESLDESLDESLDESLREKQEAGKNGDWLDIFLSFVFNKKQ SSDLKETLNQEPRSNVEQNIATTPTPIQGLPPEARDLLDERGDFSKFTLGDMEMLDVERLNQLLIHNNALSSMLMGSHSN IKPEKVSLLYGDNGGPEARHDWNATVGYKNQQGNNVATLINAHLKNSSGLIIAGNENGINNPSFYLYKKDQLTGLEQALS QEEIQNKLGFMEFLAQNSARHVGLNNLSKEEKEKFQTEIGNFQKDPKAYLDTLGSDHIAFVSKKDQKHLALVTEFGNGEL SYTLKDYGKKPDRALDRETKTTLQGNLKDDGVMFVNYSNFKYTNASKSPNEGIGATNGVSHLEANFSKVAVFNLPDLNGL AVSSFARRNLEDKLAAKGLSGKESNKIIKDFLNSNKELLEKVLNFNKAVAEAKNTGNYGGVKKAQKDLEKSIRKRELLEK EVTKQFESKSGNKNKMEAKAQANSQKDEIFKLINEGAYKEARIIAYAQNLKGIRRELRELFDKIGNINKNLKDFNQSFDA LKSGKNKDFSKVEETLKALKSSVKDLNINPEWISKVENLNVALNEFKNGKNKDFSKVTQAKSDLENSIKDVHINQQITDK VDNLNQAVLVAKATGDFSGVEQALAGLKNFNVGKNSDRSEPIYATIDDLDGSSPLKRYAKVDDLSKVGQSDSPEPIYANL GGSSPLKRHAKVDDLSKVGLSREQELTQKIGNLNQAVSEAKAGSFGNLEQTMDGLKDSTKKNVVNLWFEGARKVPISLPS SQAKLDNYATNSHTRINSNVKNGTVNEKATIMLTQKNPEWLKLVNDKIVAHNVGSTPLSDYDKIGFNQKNMKDYSDSFKF SIKLSNAVKNIKSGFVQCLTDCISAGSYSPKKAEHGVTKSGFQKS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cagA | BAD51750.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 79 |
| cagA | BAD51759.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 78 |
| cagA | BAC10429.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 76 |
| HP0547 | BAD13935.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 76 |
| cagA | BAD51747.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 75 |
| cagA | BAC10432.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 71 |
| HP0547 | BAD13990.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 71 |
| cagA | BAD51752.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 70 |
| cagA | BAD51758.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 70 |
| cagA | BAD51766.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 70 |
| cagA | NP_223213.1 | cag island protein, cytotoxicity associated immunodominant antigen | Virulence | cag PAI | Protein | 0.0 | 70 |
| cagA | AAR03939.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 70 |
| cagA | BAD51760.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 69 |
| cagA | BAD51751.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 69 |
| cagA | BAD51761.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 69 |
| cagA | AAF17598.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 69 |
| cagA | AAC44706.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 68 |
| cagA | BAD51756.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 67 |
| cagA | YP_005774524.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 67 |
| cagA | BAC10419.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 67 |
| cagA | BAD51755.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAC10431.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 66 |
| HP0547 | BAD13963.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAD51753.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAC10420.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | YP_005777288.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAD51754.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | YP_005775747.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAC10435.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 66 |
| HP0547 | BAD14072.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 66 |
| HP0547 | BAD13880.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | AAF17597.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAC10421.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 66 |
| HP0547 | BAD13799.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | YP_005779046.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAD51749.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAD51762.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 66 |
| HP0547 | BAD14018.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | BAC10433.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 66 |
| cagA | AAR03909.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 65 |
| cagA | BAD51764.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 65 |
| cagA | BAC10426.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 65 |
| cagA | BAD51744.1 | cytotoxin associated protein A | Virulence | cag PAI | Protein | 0.0 | 65 |
| cagA | YP_003728762.1 | cytotoxin-associated protein A | Virulence | cag PAI | Protein | 0.0 | 65 |
| cagA | AGC69806.1 | cag pathogenicity island protein A | Virulence | cag PAI | Protein | 0.0 | 65 |
| cagA | AAR03881.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 65 |
| cagA | AAR03970.1 | CagA | Virulence | cag PAI | Protein | 0.0 | 64 |
| HP0547 | NP_207343.1 | cag pathogenicity island protein (cag26) | Virulence | cag PAI | Protein | 0.0 | 64 |
| HP0547 | BAD14045.1 | cag pathogenicity island protein | Virulence | cag PAI | Protein | 0.0 | 63 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| HPSH_04215 | YP_001910308.1 | cag pathogenicity island protein CagA | VFG0306 | Protein | 0.0 | 64 |
