Gene Information

Name : HPSH_02560 (HPSH_02560)
Accession : YP_001909992.1
Strain : Helicobacter pylori Shi470
Genome accession: NC_010698
Putative virulence/resistance : Unknown
Product : type I restriction enzyme M protein HsdM
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 494332 - 495921 bp
Length : 1590 bp
Strand : +
Note : COG0286 Type I restriction-modification system methyltransferase subunit

DNA sequence :
ATGGAAAACAAAAACACTCAAGCGGATAAATCTTCTTCACTAGAACGCAACGAATTGCACAACACCATTTGGAAAGTGGC
TAATGAATTGAGAGGCTCAGTGGATGGCTGGGATTTTAAGCAATATGTTTTAGGCATTCTTTTTTACCGCTACATTTCAG
AAAACATGGCTCATTACATCAATAAAGAAGAGCGAAAGCGCGATCCGAGTTTTGATTACGCCAAATTAAGCGATGAAGAA
GCCGAGAGCGCAAAAGAAGGCCTGATTGAAGAAAAAGGCTTTTTCATCCCGCCAAGCGCTTTATTTTGTAATGTGCTAAA
AAACGCACCCCATAACGAAGATCTCAATGTAACCTTACAAAATATTTTTAACGAAATAGAAAAATCCAGCCTAGGGTTTA
AATCAGAAGAAAATGTCAAAGGCTTGTTTGCGGATTTAGATGTCAATAGCAATAAATTAGGGAGCTCTCATAAAAATAGG
GTTGAAAAATTGAATAAAATCCTTCAAGCCATAGGGGGCATGCAATTAGGCGACTACCAAAAAAGCGGGATTGATGTTTT
TGGCGACGCTTATGAATATTTAATGGCCATGTATGCGAGCAATGCCGGCAAAAGCGGAGGGGAATTTTTCACCCCCCAAG
AAGTGAGTGAATTACTCGCTAAAATCACCCTACACAACCAAGAGAGCGTCAATAAAGTTTATGACCCATGCTGTGGGAGC
GGATCGCTACTCTTACAATTTTCTAAAGTGTTAGGCGATAAAAACGTTTCAAAAGGGTATTTTGGGCAAGAAATCAATTT
GACCACTTACAACCTTTGCCATATCAACATGTTTTTGCATGACATCAATTACTCTAAATTCCACATAGCGCATGGGGACA
CGCTTTTAGATCCAAAACATGAAGACGATGAGCCTTTTGATGCGATCGTTTCCAACCCTCCTTATTCCACTAAATGGGCG
GGCAATAGCAACCCTATTTTAATCAACGACGAGCGCTTTAGCCCGGCCGGTGTGTTAGCGCCCAAAAACGCCGCCGATCT
CGCTTTCACCATGCACATGCTTTCTTATCTGTCCAATAGCGGCACTTGCGCGATCGTGGAATTTCCCGGGGTGCTTTATA
GGGGGAATGCTGAAGCAAAAATCAGAGAACATTTAGTCAAAGAGAATTTCATTGACTGCGTGATCGCTTTACCAGACAAC
CTCTTTTTTGGAACGAGTATCGCTACTTGTATTTTAGTGCTTAAGAAAAACAAACAAGACGACACCACGCTTTTTATTGA
TGCGAGTAAGGAATTTGTCAAAGAAGGCAAGAAAAACAAGCTCAAAGAACACAACCGAGAAAAGATTTTGCAAACCTATA
CTGAAAGGAAAACAATCAAACATTTTTCCGCCCTAGCCAATATGGAGAAAATCAAAGAAAACGATTACAACCTATCCGTG
AACCGCTTCGTGGAGCAAGAAGACACTAAAGAGATCATTGACATTAAAGCGCTCAATGGTGAGATTTCTCAAATCGTAGA
AAAACAAAGCGCTTTAAGGAACAGCCTTGAATCAATCATCAAAGAGTTAGAAGAGGGGCAAAATGCATAA

Protein sequence :
MENKNTQADKSSSLERNELHNTIWKVANELRGSVDGWDFKQYVLGILFYRYISENMAHYINKEERKRDPSFDYAKLSDEE
AESAKEGLIEEKGFFIPPSALFCNVLKNAPHNEDLNVTLQNIFNEIEKSSLGFKSEENVKGLFADLDVNSNKLGSSHKNR
VEKLNKILQAIGGMQLGDYQKSGIDVFGDAYEYLMAMYASNAGKSGGEFFTPQEVSELLAKITLHNQESVNKVYDPCCGS
GSLLLQFSKVLGDKNVSKGYFGQEINLTTYNLCHINMFLHDINYSKFHIAHGDTLLDPKHEDDEPFDAIVSNPPYSTKWA
GNSNPILINDERFSPAGVLAPKNAADLAFTMHMLSYLSNSGTCAIVEFPGVLYRGNAEAKIREHLVKENFIDCVIALPDN
LFFGTSIATCILVLKKNKQDDTTLFIDASKEFVKEGKKNKLKEHNREKILQTYTERKTIKHFSALANMEKIKENDYNLSV
NRFVEQEDTKEIIDIKALNGEISQIVEKQSALRNSLESIIKELEEGQNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 3e-98 42
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 3e-98 42
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 8e-98 42
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 3e-98 42
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 7e-98 42
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 3e-98 42
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 1e-96 42
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 3e-98 42
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 4e-97 42
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 3e-98 42
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 3e-98 42
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 4e-98 42
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 3e-98 42
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 3e-98 42
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 9e-98 42
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 6e-98 42
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 6e-98 42
ORF6 BAC22943.1 - Not tested etd PI Protein 1e-97 41
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 7e-98 41
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 3e-97 41
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 2e-97 41
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 1e-97 41