Gene Information

Name : HPSH_01870 (HPSH_01870)
Accession : YP_001909854.1
Strain : Helicobacter pylori Shi470
Genome accession: NC_010698
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 358052 - 359977 bp
Length : 1926 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCGATTGAGTAACGCTGACTTAGAACGATTAAAAAGCATGGCCAACACGCTACGCTTTTTGTGTGCGGACATGATAGA
TAAGGCTAATAGCGGGCATCCGGGCGTGTGCTTGGGATTAGCCGATGTGATGGTGGTTTTAAGCTTGCACTTAAACCTAA
ACCCCACCAACCCTAAATGGCTCAACAGGGACAGGCTGGTTTTTAGCGGAGGGCATGCGAGCGCGTTAGCGTATAGTTTG
TTGCATTTGTGGGGCTTTGATTTGAGCCTAGAAGATTTAAAGCGTTTCAGGCAATTACACTCTAAAACCCCAGGACACCC
CGAATTGCACCACACCGAAGGCATTGAGATTACGACCGGGCCTTTGGGGCAAGGTTTTGCTAACGCTGTGGGCTTTAGCA
TGGCGAGTCAATACGCTCAAAACCTTTTAGACAAAGAAGCCATTTCTCATAAAGTCTATTGCTTGTGTGGGGATGGGGAT
TTGCAAGAAGGCATTAGTTATGAGAGCGCTTCTTTAGCCGGGCACCTCAACCTGAACAACCTCATTGTGATTTATGACAG
CAACCAGATCAGCATTGAAGGCGCTATCAATATTAGTTTTAGCGAACAGGTTAAGATGCGTTTTTTAGCGCAAAATTGGG
AAGTGCTAGAATGCGATGGGCATGACTATCAAGCGATTCATAACGCTTTAGAAGAAGCCAAAAAATCCACCAAACCCACG
CTTTTAATCGCCCATACGATTATTGGTAAGGGGGCTATTGGTTTAGAGGGGAGTGAAAAAACGCATGGCTCACCCCTAAA
TAAAGAAGTGTTAAAACAATCCAAAGAAAACGCTCAAATCAATCCTGATGAAAGCTTTGTCATTAGCCCAAAAAACAAAA
TGCATTTTGAAGAAGTGAAAGTTAGGGGCGTTAGTTTAGAAGCCTTATGGGAAAAATCCTTAAGCCCTAAAGCAAAAGAA
AAGATCCATGCGTTGAAGGATTTTGATTTTAACGCCATCAATTACCCCGTTTTCAAAAAAGGCGAATCTTTAGCCACGAG
AGTGAGTAACGGCATGATTTTAAACGCTATCGCTAAAGAATGCGAGGGCTTTTTGGGGGGGAGCGCGGATTTAGCCCCGT
CTAATAACACGCAATTAAAACACTCTAGCGATTTCCCTTTAGGGCAAAACTTGCATTTTGGGATCAGAGAGCATGCCATG
GGGGCTATCACTAACGCTTTAGCGGCGTATGGCTTGTTTGTGCCTTTTTGCGCGACCTTTTTTGTGTTTAGCGATTACTT
GATGCCTAGCATTCGTTTGAGCGCTTTAATGAAACTAAAAGCCCTTTTTATCTTTACGCATGACAGCATTGGCGTGGGCG
AAGACGGGGCGACGCACCAGCCCATAGAACAACTGAGCCATTTACGCGCTTTGCCCAATTTCTACGCTTTCAGACCCAGC
GACGCTTTTGAAAATACCGCTTGCATGCAAGTGGCGTTAAGTTTGAGCGCTCCTAGCGGGCTTATTTTATCGCGCCAGAA
TTTACCCGTGCTTGATGAGGTTTCTAAAGAGCGGGTTTTAAAAGGCGCGTATGTTAAACACCACTCTAAAAATCCCATTA
TCACGCTGGTTGCGAGCGGGAGCGAAGTCTCTTTGGCTTTAGAGAGCGCTAAAATGTTAGAGCGAGAAAATATCCCCACT
CAAGTGGTGAGCGCGCCATGCTTTGATTTATTGGTGGAACAAGATGAAAGCTATCTTAAAGAGCTTTTTAAGGGTAAAGT
TTTAGTGATTGAAGCGAGTCGCGCGATAGAGTGGTATCGTTTTGCGGATAAAATCATTGGCATGGATTCTTTTGGGAGCT
CAGCAAAGGGCGATAAACTCTTTGAAAAATTTGGCTTCAGCGTTGAAAACATCACCGCTCAAGCTAAAAGGTTACTCCAC
GCATGA

Protein sequence :
MRLSNADLERLKSMANTLRFLCADMIDKANSGHPGVCLGLADVMVVLSLHLNLNPTNPKWLNRDRLVFSGGHASALAYSL
LHLWGFDLSLEDLKRFRQLHSKTPGHPELHHTEGIEITTGPLGQGFANAVGFSMASQYAQNLLDKEAISHKVYCLCGDGD
LQEGISYESASLAGHLNLNNLIVIYDSNQISIEGAINISFSEQVKMRFLAQNWEVLECDGHDYQAIHNALEEAKKSTKPT
LLIAHTIIGKGAIGLEGSEKTHGSPLNKEVLKQSKENAQINPDESFVISPKNKMHFEEVKVRGVSLEALWEKSLSPKAKE
KIHALKDFDFNAINYPVFKKGESLATRVSNGMILNAIAKECEGFLGGSADLAPSNNTQLKHSSDFPLGQNLHFGIREHAM
GAITNALAAYGLFVPFCATFFVFSDYLMPSIRLSALMKLKALFIFTHDSIGVGEDGATHQPIEQLSHLRALPNFYAFRPS
DAFENTACMQVALSLSAPSGLILSRQNLPVLDEVSKERVLKGAYVKHHSKNPIITLVASGSEVSLALESAKMLERENIPT
QVVSAPCFDLLVEQDESYLKELFKGKVLVIEASRAIEWYRFADKIIGMDSFGSSAKGDKLFEKFGFSVENITAQAKRLLH
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-97 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 4e-86 41