Gene Information

Name : hemC (HPSH_01235)
Accession : YP_001909731.1
Strain : Helicobacter pylori Shi470
Genome accession: NC_010698
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 231380 - 232300 bp
Length : 921 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
GTGGGAAATTTAGTGATTGGCTCTAGGGGGAGCGAATTAGCCTTATGGCAAGCGAATCACATTAAAGAACGCCTGAAAAA
AGAATGCTCTATAGAAAGCGAGATTCAAATCGTTAAGACTAAGGGCGATAAGATCTTAGACACCCCTTTAAATAAGATTG
GCGGTAAGGGGCTATTCACTAAGGAATTAGAAGAATTGCTTTTAAAAGGCGAAATTGATCTGGCGGTGCATTCTTTAAAA
GATGTGCCGGTCGTGTTTGAAAAGGGGTTAGACTTGGCATGCATCACTAAAAGGGCTGATGTGAGGGACACTTTTTTAAG
CGTGAAATTCCCTGATTTGATGAGCTTGCCTAAAGGGGCAAAGGTTGGCACGACTTCCTTAAGGCGCTCCATGCAACTCA
AACTAAAACGCCAGGATTTGGACACAGAAAGCTTGAGAGGGAATGTCCAAACCCGTTTGAAAAAGCTTGAATGCGGAGAA
TTTGACGCTATCATTTTGGCTGAAGCCGGGTTGTGCCGCCTAGAAATTCAAGGAGCGAAATACCGCAAGGCTTTTAGCGT
GGAAGAAATGATTCCTAGCATGGGTCAGGGGGCTTTAGGGGTAGAAATGCTCAAAAGCCACAAGCATTTTGCCACGCTTC
AAAAACTCAACGATGAAGAGAGCGCGTTTTGCTGCCATTTGGAAAGGGCGTTTGTTAAGGGGCTTAATGGAGGGTGTCAG
ATCCCTATTGGCGTGCATGCGAGTTTAATGGGTGATAGGGTTAAAATCCGGGCGGTTTTAGGCTTGCCTAACGGGAAAGA
AGTCATCGCTAAAGAAAGGCAAGGGGATAAAACTAAGGCGTTTGATCTGGTTCAAGAGCTTTTAGAAGCGTTTTTGCAAA
GCGGGGCTAAAGAGATTTTAGAAAAGGCGCAGTTGTTTTAA

Protein sequence : 
MGNLVIGSRGSELALWQANHIKERLKKECSIESEIQIVKTKGDKILDTPLNKIGGKGLFTKELEELLLKGEIDLAVHSLK
DVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGE
FDAIILAEAGLCRLEIQGAKYRKAFSVEEMIPSMGQGALGVEMLKSHKHFATLQKLNDEESAFCCHLERAFVKGLNGGCQ
IPIGVHASLMGDRVKIRAVLGLPNGKEVIAKERQGDKTKAFDLVQELLEAFLQSGAKEILEKAQLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-43 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-43 46