Gene Information

Name : HPSH_07585 (HPSH_07585)
Accession : YP_001910938.1
Strain : Helicobacter pylori Shi470
Genome accession: NC_010698
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1473685 - 1474932 bp
Length : 1248 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATAAAAAACTTTTATTGCAAGATTTTGAGATGGTGGCTCTTTCTTTAAAAAAGCGTAATAATGCGATGGATGA
TGCATTGGAGCGCTTGCGCGAAGTCATCACGCATTATAAAAAGCAACTCATTGAATTAGAAGGCTTGCAAGCCTTTCAAA
ACAAGGTTTCTAAAGAATTTGGTATCAAAATGGCTCAAAAAGTGGATACAAGCGATCTCAAAAAAGAGCTAGAAAACAAT
AAAATCAAACTGAATGAGCTTTCCAAAAGCGTGGGCGAATTGGAACAACAAATAGATTTAAGGCTTTCAATAATCCCTAA
TCTGGTGGATGAAAAAACCCCTTTAGGCGCAAGCGAAGAAGACAACATAGAAATTAAAAAAATCTTAACCCCTAGAAATT
TCACTTTCAAACCCAAAGAGCATTTTGAACTCGCTCAACAAAATGGCTGGATTGATTTTGAAAGTGGCGTGAAACTCGCT
AAAAGCCGTTTTTCTGTCATTAGGGGTTTTGGGGCTAAAATTTATCGCGCGCTCATCCATTTAATGTTGGATTTTAATGA
AAAAAATGGCTTTGAAATCATCTACACGCCGGCGTTAGTGAATGAAAAAATGCTTTTTGGGACCGGGCAATTGCCCAAAT
TCAAAGAAGATGTTTTCAAAATAGAAAATGAAAATTTGTATCTGATCCCTACCGCTGAAGTAACGCTCACTAATCTATAC
AACGACACGATTGTTAGCGTTGAAAAACTCCCTATTAAAATGACCGCGCACACGCCTTGTTTTAGGAGTGAAGCAGGGAG
TGCGGGCAAGGACACAAGAGGGATGATAAGACAGCACCAGTTTGATAAAGTGGAGCTAGTGGCTATCACGCACCCTAAAG
AAAGCGATGCCATGCAAGAGCATATGCTAGAGAGCGCGAGCGAAATTTTAAAGGCTTTGGAATTACCGCACCGGTTTGTG
CAATTGTGCAGCGCGGATTTAGGCTTTAGCGCAAGCAACACCATAGATATTGAAGTGTGGCTGCCCGGGCAAAATTGCTA
CAGAGAAATCAGCTCGGTGTCTAACACGAGGGATTTTCAAGCCAGGCGCGCGAAAATCCGCTTCAAAGAGAATCAAAAAA
ACCAATTAGCGCACACCTTAAACGGCTCTTCTTTAGCGGTAGGCAGGACGATGGTCGCTTTAATGGAAAACCACCAGCAA
GCGGATGGGAGCATCCATATTCCTAAGGCGTTAGAAAAATACCTTTAA

Protein sequence :
MIDKKLLLQDFEMVALSLKKRNNAMDDALERLREVITHYKKQLIELEGLQAFQNKVSKEFGIKMAQKVDTSDLKKELENN
KIKLNELSKSVGELEQQIDLRLSIIPNLVDEKTPLGASEEDNIEIKKILTPRNFTFKPKEHFELAQQNGWIDFESGVKLA
KSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLY
NDTIVSVEKLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDAMQEHMLESASEILKALELPHRFV
QLCSADLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQ
ADGSIHIPKALEKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-77 45