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Name : HPSH_00530 (HPSH_00530) Accession : YP_001909598.1 Strain : Helicobacter pylori Shi470 Genome accession: NC_010698 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase/cystathionine beta-lyase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 4.4.1.8 Position : 100423 - 101565 bp Length : 1143 bp Strand : - Note : catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine and L-cysteine; or Cystathionine beta-lyase (CBL) can convert cystathionine to homocysteine DNA sequence : ATGCGCATGCAAACAAAATTAATCCATGGGGGCATTAGTGAGGATGCGGCAACGGGGGCGGTGAGTGTGCCTATTTATCA AACTTCCACCTACCGCCAAGGTGCCATAGGCCGCCACAAGGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG CTTTAGAAGAACTCATCGCTGATTTAGAAGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGTTTAGCTGGAATCCATGCC GTTTTTTCTCTCTTGCAATCAGGCGATCATGTGCTATTAGGCGATGATGTCTATGGGGGGACTTTTCGCTTGTTCAATAA AGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATCTATCCCAAATCAAAAAGGCTATCAAACCCA ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGTGCAATGCGCTAGTGTCGCT AAAGATCATGGTTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTGCCAAAACCCGCTTCTTTTGGGAGCGGA TATTGTAGTGCATAGCGGCACCAAATACTTAGGCGGGCATAGCGATGTGGTCGCTGGGCTTGTAACCACTAATAATGAAG CACTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGCTGGCTGTTGCAAAGA GGGATTAAAACGCTAGGATTGCGCATGGAGGCCCATCAAAAAAACGCCCTTTGCGTGGCTGAGTTTTTAGAAAAACACCC TAAAGTGGAGAAGGTCTATTACCCAGGCTTAAGCGCTCACCCTAACCACGAACTGGCCAAAAAACAGATGCGTGGCTTTA GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAGGCGGTTGCTTTTGTAGAAAGCCTTAAACTATTCATTTTAGGC GAGAGTTTGGGCGGGGTGGAAAGTTTGGTGGGAGTTCCGGCGCTTATGACCCATGCGTGTATCCCCAAAGCGCAACGAGA AGCTGCCGGGATTAGAGATGGCTTGGTGCGCTTGTCTGTGGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC AAGCGTTCGCTAAAATAGGCTAA Protein sequence : MRMQTKLIHGGISEDAATGAVSVPIYQTSTYRQGAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLVQCASVA KDHGLLTIVDNTFATPYCQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR GIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLSAHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFILG ESLGGVESLVGVPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-97 | 55 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 1e-98 | 55 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 5e-74 | 48 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| HPSH_00530 | YP_001909598.1 | cystathionine gamma-synthase/cystathionine beta-lyase | BAC0207 | Protein | 2e-62 | 43 |
