Gene Information

Name : murD (ETA_07530)
Accession : YP_001906697.1
Strain : Erwinia tasmaniensis Et1/99
Genome accession: NC_010694
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 842954 - 844270 bp
Length : 1317 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCTGACTATCTGGGTAAAAAAGTGGTCATTATCGGGTTGGGCCTGACCGGCCTCTCCTGTGTTGATTTCTTTATCGC
GCGCGGCGTTGTGCCGCGCATGATAGATACCCGTGTCGTGCCACCGGGGCTGGAAAAGCTGCCGAAAAACGTTGAGCGCT
GGCTGGGGTCGATGAACGACAGCTGGCTGTTGGATGCCGATCTGATCGTTGCCAGCCCCGGCGTGGCGCTGGCGCATCCT
TCTTTGATCGCTGCGGCGCAGGCCGGAGTGGAGATCGTTGGCGATGTTGAGCTGTTCTGCCGCGAAGCGCAGGCACCGAT
CGTGGCGATCACCGGTTCCAACGGTAAAAGCACCGTGACGACGCTGGTCGGCGAGATGGCAAGAGCCGCAGGCTGGCAGG
TTGGCGTAGGGGGCAATATTGGCCTGCCCGCACTGACGCTGTTGCAGCAGCCTGCCCAGCTGTATGTGCTGGAGCTGTCG
AGCTTCCAGTTGGAAACCACCAGCAGCCTGAAAGCGGCGGCGGCGACCCTCCTCAACGTGACCGAAGATCATATGGATCG
CTACCCGCTCGGCATGCAGCAATATCGCGCTGCCAAGCTGCGCATCTATGAAAATGCCACGGCCTGCGTGGTCAATGCCG
ATGATGCGATGACCATGCCAATACGCGGCGCGGATGCACGCTGCGTCAGTTTTGGTGCCGACTTCGGCGACTATCACCTT
ACGCGCCAGCAGGGCAGCACCTGGCTGCGTGTGCAGGGGGAAAAAGTGCTGAATACCGACGAAATGCACCTGGTCGGTCA
GCATAACTATACGAATGCCCTGGCGGCGCTGGCGCTGGCGGATGCCGTTGGCCTGCCGCGCGCTACCAGCCTGAAAGCCT
TAACGACCTTTAACGGCTTGCCGCACCGTTTTCAGCTGGTTCATGAACATAACGGTGTGCGCTGGATCAACGATTCCAAA
GCCACCAATGTTGGCAGCACCGAGGCGGCGCTGAATGGTTTACATCCAGCCGGTACCTTGTGGCTGCTGCTGGGCGGAGA
CGGCAAGTCGGCGGATTTTACGCCCCTCACCCGTTATTTGCAGGGCGAGCGCATTCGGGTGTACTGCTTCGGTCGTGACG
GCGCTGAACTGGCGGCCCTGCGTCCGGAAATAGCGGTACAAACGGCGACGATGGCGGAAGCCGTGCGGCAGATTGCCGCT
CAGGTGCGGCCTGGCGACCTGGTGCTGTTGTCGCCAGCCTGTGCCAGCCTTGACCAGTTTAAAAACTTCGAGCAGCGCGG
CGATCTGTTTGCCCAACTGGCGCGGGAGGCTGGCTGA

Protein sequence :
MADYLGKKVVIIGLGLTGLSCVDFFIARGVVPRMIDTRVVPPGLEKLPKNVERWLGSMNDSWLLDADLIVASPGVALAHP
SLIAAAQAGVEIVGDVELFCREAQAPIVAITGSNGKSTVTTLVGEMARAAGWQVGVGGNIGLPALTLLQQPAQLYVLELS
SFQLETTSSLKAAAATLLNVTEDHMDRYPLGMQQYRAAKLRIYENATACVVNADDAMTMPIRGADARCVSFGADFGDYHL
TRQQGSTWLRVQGEKVLNTDEMHLVGQHNYTNALAALALADAVGLPRATSLKALTTFNGLPHRFQLVHEHNGVRWINDSK
ATNVGSTEAALNGLHPAGTLWLLLGGDGKSADFTPLTRYLQGERIRVYCFGRDGAELAALRPEIAVQTATMAEAVRQIAA
QVRPGDLVLLSPACASLDQFKNFEQRGDLFAQLAREAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 8e-57 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 8e-57 43