Gene Information

Name : thyA (ETA_27590)
Accession : YP_001908676.1
Strain : Erwinia tasmaniensis Et1/99
Genome accession: NC_010694
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3074206 - 3075000 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATCTGGCGTTAATGCAGCATGTGCTTGAACAGGGCACGCCGAAAGACGATCGTACCGGCACCGGCACGCT
GTCCGTTTTTGGTCACCAGATGCGTTTCAATCTGCAACAGGGTTTCCCGCTGGTCACCACCAAAAAGTGCCATCTGCGCT
CGATTATTCATGAGCTGCTGTGGTTCCTGAAAGGGGAGACCAATATCGCCTACCTGAAAGAAAACAAGGTGTCGATTTGG
GACGAATGGGCAGACGAAAACGGCGATCTCGGCCCGGTGTACGGCAAGCAGTGGCGCAGCTGGGGAGCCGCAGACGGGCA
TCAGATTGACCAGCTTAGCAAGGTGATTGAGCAGCTAAAAAGCGATCCTGACTCGCGGCGTATTATTGTCTCGGCCTGGA
ACGTGGGGGAACTGGATCAGATGGCGCTGGCTCCGTGCCACGCCTTTTTCCAGTTCTATGTGGCGCAGGGGAAACTATCC
TGCCAGCTTTATCAGCGTTCTTGCGATATTTTCCTCGGCCTGCCTTTCAACATCGCCAGCTATGCTTTGCTGGTGCATAT
GATCGCCCAGCAGTGCGACCTTGAAGTCGGTGATTTTGTCTGGACCGGCGGTGATACCCACCTTTACAGCAATCACCTCG
AACAGGCGCGGCTACAGCTGCAGCGTGAACCGCGGGCGTTGCCAAAACTGGTGATTAAGCGCAAGCCGGACTCGTTGTTC
GACTATCGTTTCGACGATTTCGAGATAGAAGGTTACGACCCGCACCCGGCGATTAAAGCCCCGGTGGCTATCTGA

Protein sequence :
MKQYLALMQHVLEQGTPKDDRTGTGTLSVFGHQMRFNLQQGFPLVTTKKCHLRSIIHELLWFLKGETNIAYLKENKVSIW
DEWADENGDLGPVYGKQWRSWGAADGHQIDQLSKVIEQLKSDPDSRRIIVSAWNVGELDQMALAPCHAFFQFYVAQGKLS
CQLYQRSCDIFLGLPFNIASYALLVHMIAQQCDLEVGDFVWTGGDTHLYSNHLEQARLQLQREPRALPKLVIKRKPDSLF
DYRFDDFEIEGYDPHPAIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-84 62