Gene Information

Name : tpx (ETA_16460)
Accession : YP_001907585.1
Strain : Erwinia tasmaniensis Et1/99
Genome accession: NC_010694
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.-
Position : 1862357 - 1862860 bp
Length : 504 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence :
ATGTCTCAGACCGTACATCTTCAGGGCAATCCGGTTTCCGTCGATGGCCAGTTGCCAACCTCTGGCCAGACGGCACGGCC
TTTCACCCTGGTCGCTAAAGACCTCTCGGATGTCTCACTTGCGCATTATGCGGGAAAACGTAAGGTACTGAATATCTTCC
CAAGCGTTGATACCGGCGTGTGCGCGACCTCAGTGCGTAAATTTAACCAGCTGGCCAGTGAGCTCACCAATACCGTGGTA
CTGTGCATCTCTGCCGATCTGCCCTTTGCGCAGTCACGTTTCTGCGGTTCGGATGGTTTGAGCAACGTCGTGACCCTTTC
TACCCTGCGCGGCAACGCTTTCCTTAAAGATTACGGCGTGGCGATCATCGACGGCCCACTCAATGGCCTTGCCGCACGCG
CCGTCGTGGTGCTTGACGAGAACGATCGGGTGATTTACAGCCAGCTGGTTGATGAAATTTCCAGTGAGCCGGATTATGAC
GCAGCGCTGGCAAGCCTGAAGTAG

Protein sequence :
MSQTVHLQGNPVSVDGQLPTSGQTARPFTLVAKDLSDVSLAHYAGKRKVLNIFPSVDTGVCATSVRKFNQLASELTNTVV
LCISADLPFAQSRFCGSDGLSNVVTLSTLRGNAFLKDYGVAIIDGPLNGLAARAVVVLDENDRVIYSQLVDEISSEPDYD
AALASLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 7e-33 48
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 7e-33 48
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 4e-33 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 4e-33 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001907585.1 thiol peroxidase VFG0087 Protein 2e-33 48