Gene Information

Name : guaA (ETA_10360)
Accession : YP_001906979.1
Strain : Erwinia tasmaniensis Et1/99
Genome accession: NC_010694
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1154778 - 1156358 bp
Length : 1581 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACGACGGAAAATATTCATAAACATCGCATCCTGATCCTCGATTTCGGTTCACAGTACACCCAGCTGGTCGCACGCCG
CGTGCGCGAGCTGGGCGTCTACTGCGAGCTGTGGGCGTGGGACGTTACCGAAGAGCAGATCCGTGGGTTCAATCCTAACG
GCATCATCCTCTCCGGCGGTCCGGAAAGCACCACCGAGCACGACAGCCCGCGTGCCCCGGACTACGTGTTCAACGCCGGT
GTACCGGTGCTGGGCGTGTGCTACGGCATGCAGACGATGGCGCTGCAGCTGGGCGGCAAGGTGGAAGGCTCCAGCGAGCG
CGAGTTCGGCTATGCCCAGGTGGAAGTGAAAAACCAGAGCGCGCTGATCCGCGATATCGAAGATGCCATCAGCGCAGACG
GCAAGCCGCTGCTGGACGTGTGGATGAGCCACGGTGATAAAGTCACCGCCATCCCGTCTGATTTTGTCACCGTTGCCAGC
ACCGACACCTGTCCGTTTGCCATTATGGCTAACGAAGAGAAACGTTTCTACGGCGTGCAGTTTCACCCAGAAGTGACGCA
TACCCGTCAGGGGCTGCGCCTGCTGGAGCGCTTCGTGCGCGATATCTGCCTGTGTGAAGCGCTGTGGACGCCTGCTAAGA
TCATCGAAGATGCCGTTGAACGTCTGCGCGAGCAGGTGGGTGACGACAAGGTGATCCTGGGCCTGTCCGGCGGCGTTGAC
TCATCCGTTACCGCAATGCTGCTGCATCGCGCTATTGGCGACCGTCTGACCTGCGTGTTCGTTGATAACGGCCTGCTGCG
CCTGAATGAGGCGGAGCAGGTGATGGAGATGTTCGGTGACCACTTCGGCCTGAATATTATCCACGTGGCGGCGGAAAACC
GTTTCCTTGACGCGCTGGCCGGCACCGATGAACCGGAAGCCAAGCGCAAGATTATTGGGCGCGTCTTCGTTGAAGTATTC
GATGAAGAAGCCACTAAGCTCAATGATGTGAAATGGCTGGCGCAGGGCACTATCTACCCTGACGTGATCGAATCTGCCGC
TTCGGCGACCGGTAAGGCACACGTGATTAAATCACACCATAACGTTGGCGGCCTGCCAAAAGAGATGAAGCTGGGTCTGG
TTGAACCGCTGAAAGAGCTGTTCAAAGATGAAGTGCGCAAAATTGGTCTTGAGCTGGGCCTGCCGCACGCCATGCTGTTC
CGTCACCCGTTCCCTGGACCAGGGCTGGGTGTGCGCGTACTGGGCGAAGTGAAAAAAGAGTACTGTGACCTGCTGCGCCG
TGCCGATGCTATCTTTATTGAAGAGCTGCATAAAGCCGACCTGTATAACAAGGTCAGCCAGGCGTTCACCGTGTTCCTGC
CGGTGCGTTCCGTAGGCGTGATGGGCGATGGCCGCAAGTACGACTGGGTCGTTTCCCTGCGTGCGGTAGAAACCATCGAC
TTTATGACCGCGCACTGGGCGCATCTGCCGTATGAGTTCCTCGGCCGCGTTTCAAACCGCATCATCAACGAAATCGACGG
TATTTCCCGCGTGGTTTACGATATCTCTGGAAAACCACCGGCGACTATTGAGTGGGAATGA

Protein sequence :
MTTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEEQIRGFNPNGIILSGGPESTTEHDSPRAPDYVFNAG
VPVLGVCYGMQTMALQLGGKVEGSSEREFGYAQVEVKNQSALIRDIEDAISADGKPLLDVWMSHGDKVTAIPSDFVTVAS
TDTCPFAIMANEEKRFYGVQFHPEVTHTRQGLRLLERFVRDICLCEALWTPAKIIEDAVERLREQVGDDKVILGLSGGVD
SSVTAMLLHRAIGDRLTCVFVDNGLLRLNEAEQVMEMFGDHFGLNIIHVAAENRFLDALAGTDEPEAKRKIIGRVFVEVF
DEEATKLNDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPHAMLF
RHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETID
FMTAHWAHLPYEFLGRVSNRIINEIDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-130 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-130 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-130 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-112 47