Gene Information

Name : tpx (Rpic_3035)
Accession : YP_001900590.1
Strain :
Genome accession: NC_010682
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 3162249 - 3162749 bp
Length : 501 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCAAACGTGACCCTTGGCGGCAACCCGATCGAAGTCGGCGGCCAATTCCCGACCGCAGGCTCGAAGGCCCCGGCATT
CACGCTGGTCGGCGCAGACCTGAAAGACGTGTCGCTCGCTGACTTTGCCGGCAAGCGCAAGGTCCTGAACATCGTGCCGA
GCCTGGACACCCCGGTGTGCGCCACCTCCACGCGCAAGTTCAACGAAGCCGCTGCCAAGCTGGACAACACGGTCGTGCTG
TCCATCTCTGCCGACCTGCCGTTCGCAGCCGGCCGCTTCTGCACCACCGAGGGCATCGCGAATGTGAAGCCGCTGTCGAC
CTTCCGCGACAAGGGTTTCAAGCAAGCCTACGGCGTCGACATCACGTCGGGCCCGCTGGCTGGCGTGACCGCCCGCGCCG
TGGTCGTGCTCGACGCCGACGACACCGTCATGTACTCGCAACTCGTGCCCGAGATCAAGGACGAGCCGAACTACGACGCG
GCCCTGTCTGCGCTGAAGTAA

Protein sequence : 
MANVTLGGNPIEVGGQFPTAGSKAPAFTLVGADLKDVSLADFAGKRKVLNIVPSLDTPVCATSTRKFNEAAAKLDNTVVL
SISADLPFAAGRFCTTEGIANVKPLSTFRDKGFKQAYGVDITSGPLAGVTARAVVVLDADDTVMYSQLVPEIKDEPNYDA
ALSALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 1e-34 47
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 6e-35 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 8e-35 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 4e-35 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001900590.1 thiol peroxidase VFG0087 Protein 2e-35 47