Gene Information

Name : Rpic_1815 (Rpic_1815)
Accession : YP_001899384.1
Strain :
Genome accession: NC_010682
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1907239 - 1909641 bp
Length : 2403 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: rme:Rm

DNA sequence :
GTGAGCGAGTGCGGCTCCAAGGGATGCGGCTGTGCTGCCCCTAGCGTGGTGACGCCGGCGGACGTCGATACGGCCAGTGT
CGACCTGAAGCGATCCCGCTATCAGATCGACAACATGGACTGCCCGACCGAAGAAGCGCTCATTCGCAATAAGCTTGCGG
CGCTGCCCGGCGTGGTGAAGCTTGAGTTCAACCTGATGCAGCGCTCGCTGGCCGTACACCACCAGTTGCCATCTCCGGCG
CCGATCGAGCAGGCGTTGTCAGCGATTGGCATGCGAGCGATTCGCTCGGACGAAACCTCTGCCGGGCAGAGCACGGTCCT
GACCATCCGCCAGATGGACTGCCCGACCGAGGAGACGCTGATTCGCGGCAAGCTCGCAGGACTGCCTGGTGTGACCGGCC
TTGATTTCAACCTCGTCCAGCGCACGCTCGCGGTCCATCACGCCGCGGGCTCGTTGCCGCAAGTGCTGGCCGCCATTCAA
TCGCTCGGCTTTGAGGCCGAGGTCCGCGACACGTCTGCCGCTGCACCCGCTTCCGCCCAGGATGCCACGCCCACCAAATG
GTGGCCGCTTGCCATTGCGGGCACCAGCGCCGTGTTGGCGGAAGTGGTCTATTGGCTCAACGGCGGCAATCACTGGGTTG
TGGTGGTCCTGGCGCTGGCCGCGATCCTGACCGGTGGGCTGTCCACCTACAAGAAAGGCTGGATCGCGCTCAAGAACCGC
AACTTGAACATGAATGCCCTCATGTCGATCGCGGTCACGGGGGCGATGGTGATCGGCCACTGGCCGGAAGCAGCGATGGT
GATGGTCCTCTTCGCCCTGGCTGAAGTCATCGAAGCCCGCTCGCTTGACCGCGCTCGCGACGCGATTCGCGGCCTGATGG
ATCTTGCCCCGGAGACGGCCACGGTTCTGCATAGCGATGGCAGTTGGACCGACGTCGATGCCAAGTCCGTCGAGGTCGGC
AGCCGGGTACGGGTCAAGCCGGGCGAGCGTATCGCGCTCGATGGCACGGTCCTGCAGGGACGCTCCTCCGTCAATCAGGC
GCCGATTACCGGCGAGAGCCTGCCGGTCGAGAAAGCTGAAGGCGACCCCGTGTTCGCCGGCACCATCAACGAGTCCGGAT
CGTTCGAGTATCGCGTTACTGCTACGGCGAACGACTCCACACTGGCTCGTATCATTCACGCAGTCGAGGCTGCTCAAGGC
AGTCGAGCACCCACGCAGCGCTTTGTCGACCAGTTCGCCCGGCTGTACACGCCCATCGTGTTCGCGGTCGCACTGCTGGT
GGCGATCATCCCTCCGCTGGTCTTCGGTGCAGCCTGGCTGGGCTGGATCTACAAGGCCCTGGTTCTCCTGGTGATCGCTT
GCCCCTGTGCCCTCGTGATTTCGACGCCGGTAAGTATTGTGAGCGGCCTGGCCGCTGCCGCACGGCGCGGCATCCTCATC
AAGGGCGGGGTCTATCTCGAGGAAGGCCGCAAGCTGAAATGGTTGGCGCTGGACAAGACCGGCACCATCACACATGGCAA
GCCGGCGCAGACCGACGTCCTGGCCTGGAACGGTGCGGACGCATCTGCCGCCCAATTCCTGGCTGCCAGCCTGGCGGCTC
GTTCCGATCACCCCGTCTCCCAAGCCGTGGCCCGTGCGGCGCGGGACACAGCTCAAGCCCCACGCGACGTCACCGACTTT
GCGGCTTTGCCCGGGCGCGGCGTCCAGGGTCATATCGACGGCGCGCTCTATCACCTTGGCAACCATCGCCTGGTCGAGGA
ACTCGGTGTGTGCTCACCGGCGCTGGAAGCCAACCTTGCCGCGCTTGAAACCCAGGGCAAGACCGTTGTGATGCTGATCG
GCCCGGACGGCGTACGCGCGCTGTTCGGCGTGGCCGATACCATCAAGGACAGCAGTCGCCAAGCCATCAAGGATTTGCAT
GCTCTGGGCATCAAGACCCTGATATTGAGTGGCGACAATCCGCACACCGCCGAGGCAATCGCGCAGCAGGTCGGTATCGA
CGAGGCTCGGGGCAACCTGCTGCCGGAAGACAAGCAGCGCGAAATCGAGCAGCTATCCGCACAGGGGACCATCGGCATGG
TCGGCGATGGCATCAACGACGCGCCGGCTCTGGCGCGGGCCGATATTGGATTCGCAATGGGCGCCGCAGGCACGGACACT
GCGATCGAAACGGCCGACGTCGCGCTGATGGACGACGATCTGCGCAAGCTTCCGGCCTTCGTACGGCTCTCGCGGTCCAC
GGCTGGAGTGCTGAAGCAGAACATTGCGTTGGCGCTTGGCATCAAGGTCGTATTCCTGGTGTTGACCTTTACCGGCCAGG
CCACCATGTGGATGGCCGTGTTTGCCGACATGGGCGCCAGCCTGCTGGTGGTCGGCAACGGGTTGCGGCTGCTGCGCAAA
TGA

Protein sequence :
MSECGSKGCGCAAPSVVTPADVDTASVDLKRSRYQIDNMDCPTEEALIRNKLAALPGVVKLEFNLMQRSLAVHHQLPSPA
PIEQALSAIGMRAIRSDETSAGQSTVLTIRQMDCPTEETLIRGKLAGLPGVTGLDFNLVQRTLAVHHAAGSLPQVLAAIQ
SLGFEAEVRDTSAAAPASAQDATPTKWWPLAIAGTSAVLAEVVYWLNGGNHWVVVVLALAAILTGGLSTYKKGWIALKNR
NLNMNALMSIAVTGAMVIGHWPEAAMVMVLFALAEVIEARSLDRARDAIRGLMDLAPETATVLHSDGSWTDVDAKSVEVG
SRVRVKPGERIALDGTVLQGRSSVNQAPITGESLPVEKAEGDPVFAGTINESGSFEYRVTATANDSTLARIIHAVEAAQG
SRAPTQRFVDQFARLYTPIVFAVALLVAIIPPLVFGAAWLGWIYKALVLLVIACPCALVISTPVSIVSGLAAAARRGILI
KGGVYLEEGRKLKWLALDKTGTITHGKPAQTDVLAWNGADASAAQFLAASLAARSDHPVSQAVARAARDTAQAPRDVTDF
AALPGRGVQGHIDGALYHLGNHRLVEELGVCSPALEANLAALETQGKTVVMLIGPDGVRALFGVADTIKDSSRQAIKDLH
ALGIKTLILSGDNPHTAEAIAQQVGIDEARGNLLPEDKQREIEQLSAQGTIGMVGDGINDAPALARADIGFAMGAAGTDT
AIETADVALMDDDLRKLPAFVRLSRSTAGVLKQNIALALGIKVVFLVLTFTGQATMWMAVFADMGASLLVVGNGLRLLRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 70
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 5e-122 48
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 7e-125 47
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 7e-125 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rpic_1815 YP_001899384.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 79
Rpic_1815 YP_001899384.1 heavy metal translocating P-type ATPase BAC0461 Protein 5e-86 43
Rpic_1815 YP_001899384.1 heavy metal translocating P-type ATPase BAC0455 Protein 9e-93 41