Gene Information

Name : Rpic_1787 (Rpic_1787)
Accession : YP_001899357.1
Strain :
Genome accession: NC_010682
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1882384 - 1884069 bp
Length : 1686 bp
Strand : +
Note : TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; Heavy metal transport/detoxification protein; KEGG: pol:Bpro_2

DNA sequence : 
ATGACCCATCTGAAGATCACTGGAATGACCTGCGATTCGTGTGCCGTCCACGTCAAGGATGCCTTGGAGAAGGTGCCGGG
CGTGCGGTCGGCGGTCGTATCCTATCCGAAGGGGACGGCGCAAATCGCTACCGACCCCGGCACTTCGACGGATGCGCTGA
CTGCGGCCGTGGCCGGACTCGGCTACCGGGTCATGCTCGGTGAGGCCCCGCCAGTGGAAAAACGCGGCAACCTGCTCGAC
AAGGCGCTGGGCTGGCTTGCCAGCGGTGAGAAATCCGCAGGCGAAGGCAGCGCGCTACGCATCGCCGTCATCGGCAGCGG
CGGCGCCGCGATGGCGGCGGCCCTCAAGGCCGTCGAGCAAGGCGCGCAGGTCACCCTGATCGAGCGCGGCACCATCGGTG
GCACCTGCGTCAACGTCGGCTGCGTGCCGTCCAAGATCATGATCCGCGCGGCCCATATCGCCCACCTGCGCCGCGAAAGC
CCGTTCGACGGCGGCATCCAGGCCACACCGCCGGCCATCGTGCGCGAACGCCTGCTGGCCCAGCAGCAGGGGCGCGTCGA
TGAGCTGCGCCACGCTAAGTACGAGGGCATCCTGGCCAGCACCCCGGCCATCACGGTGCTGCGCGGCGAGGCCCGCTTCC
AGAACGGGCATGCCCTGAGCGTGCGCCTGGCCGAGGGCGGTGAGCGCGAGGTGGCATTTGACCGCTGCCTGATCGCCACG
GGCGCCAGCGCGGCCGTGCCGCCGATCCCCGGCCTGAAGGACACCCCATACTGGACCTCGAACGAGGCGCTGGCCAGCGA
CACCCTGCCCAAGCGGCTGGCCGTGATCGGCTCGTCGGTGGTGGCCGTGGAGCTGGCGCAGGCATTCGCCCGGCTGGGCA
GCCAGGTCACGGTCCTGGCGCGCAGCACGCTGTTCTTCCGTGAGGATCCGGCCATCGGCGAGGCCGTGACGGCCGCGTTC
CGCGCCGAGGGCATCACGGTGCTGGACCACACGCAGGCCAGCCAGGTGGCCTACGCGAACGGTGAATTCGTGCTCACCAC
CGGGCACGGTGAAATCCGCGCCGACCAGTTGCTGGTCGCCACCGGCCGCGCGCCGAACACGCGTGAGCTGGCGCTGGAGG
CGGCGGGGGTGAGGGACAACGCGCAAGGGGCCATCGTCATCGACAAGGCGATGCGCACCAGCGCACAGAACATCTACGCC
GCCGGCGATTGCACCGACCAGCCGCAATTCGTCTATGTGGCCGCAGCGGCCGGCACCCGCGCGGCGATCAACATGACCGG
AGGCGATGCCGCGCTCGATCTGAGCGCCGTGCCGGCGGTGGTGTTCACCGACCCGCAGGTCGCCACCGTTGGCTACAGCG
AAGCGGAAGCGCACCACGATGGCATCGAGACCGATAGCCGGCTGCTCACGCTGGACAACGTGCCGCGGGCGCTCGCCAAC
TTCGACACGCGCGGCTTCATCAAGCTGGTCGCTGATGCTGGCAGTGGGCGCTTGATCGGCGTGCAGGCGGTGGCGCCGGA
AGCGGGTGAACTGATCCAGACGGCGGCCCTGGCAATTCGCAACCGCATGACGGTGCAGGAACTGGCCGACCAGTTGTTCC
CGTACCTGACCATGGTCGAGGGACTCAAGCTTGCCGCGCAGACCTTCTCCAAGGACGTGAAGCAGCTGTCCTGCTGCGCT
GGGTGA

Protein sequence : 
MTHLKITGMTCDSCAVHVKDALEKVPGVRSAVVSYPKGTAQIATDPGTSTDALTAAVAGLGYRVMLGEAPPVEKRGNLLD
KALGWLASGEKSAGEGSALRIAVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRES
PFDGGIQATPPAIVRERLLAQQQGRVDELRHAKYEGILASTPAITVLRGEARFQNGHALSVRLAEGGEREVAFDRCLIAT
GASAAVPPIPGLKDTPYWTSNEALASDTLPKRLAVIGSSVVAVELAQAFARLGSQVTVLARSTLFFREDPAIGEAVTAAF
RAEGITVLDHTQASQVAYANGEFVLTTGHGEIRADQLLVATGRAPNTRELALEAAGVRDNAQGAIVIDKAMRTSAQNIYA
AGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLSAVPAVVFTDPQVATVGYSEAEAHHDGIETDSRLLTLDNVPRALAN
FDTRGFIKLVADAGSGRLIGVQAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCA
G

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 84
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 84
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 84
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 84
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 84
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 83
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 83
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 83
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 83
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 78

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rpic_1787 YP_001899357.1 putative mercuric reductase BAC0652 Protein 0.0 84
Rpic_1787 YP_001899357.1 putative mercuric reductase BAC0653 Protein 0.0 80
Rpic_1787 YP_001899357.1 putative mercuric reductase BAC0650 Protein 2e-178 71